Blar i UiS Brage på forfatter "Håheim, Katja Stangeland"
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Mapping the Antimicrobial Activity of Indoloquinoline and Neocryptolepine Analogues
Håheim, Katja Stangeland; Albrigtsen, Marte; Helland, Kirsti; Andersen, Jeanette Hammer; Sydnes, Magne Olav (Peer reviewed; Journal article, 2023) -
Photodegradable Antimicrobial Agents: Towards Structure Optimization
Alves Souto de Aquino, Gabriel; Nguyen van Sang, Liza Maëva; Valery, Romane; Lanave, Maelys; Estopiñá-Durán, Susana; Håheim, Katja Stangeland; Baptista Ferreira, Sabrina; Sydnes, Magne Olav (Peer reviewed; Journal article, 2023)Antibiotic resistance continues to be an ominous threat facing human health globally and urgent action is required to limit the loss of human life. The pollution of antibiotics into the environment is one of the drivers ... -
Regiodivergent Synthesis of 11H-Indolo[3,2-c]quinolines and Neocryptolepine from a Common Starting Material
Håheim, Katja Stangeland; Lund, Bjarte Aarmo; Sydnes, Magne Olav (Peer reviewed; Journal article, 2023)A large number of diversely functionalized analogs of the bioactive natural products neocryptolepine and isocryptolepine have been prepared from a series of 3-bromoquinoline derivatives. The neocryptolepines were obtained ... -
Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities
Håheim, Katja Stangeland; Lindback, Emil; Tan, Kah Ni; Albrigtsen, Marte; Helgeland, Ida Therese Urdal; Clemence, Lauga; Matringe, Theodora; Kennedy, Emily K.; Andersen, Jeanette Hammer; Avery, Vicky M.; Sydnes, Magne Olav (Peer reviewed; Journal article, 2021-05)A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the ... -
Synthesis of isocryptolepine and analogues for antimalarial evaluation
Håheim, Katja Stangeland (Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-07)Malaria is considered a serious global health concern, causing 445 000 deaths annually. With the increasing apperance of drug resistant cases of Plasmodium strains, discovery of new treatments are of paramount importance. ...