Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Author "Lapin, Morten"
Now showing items 1-2 of 2
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Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer
Lapin, Morten; Edland, Karin Hestnes; Tjensvoll, Kjersti; Oltedal, Satu; Austdal, Marie; Garresori, Herish; Rozenholc, Yves; Gilje, Bjørnar; Nordgård, Oddmund (Peer reviewed; Journal article, 2023)Purpose: Circulating tumor DNA (ctDNA) has emerged as a promising tumor-specific biomarker in pancreatic cancer, but current evidence of the clinical potential of ctDNA is limited. In this study, we used comprehensive ... -
Extracellular vesicles as a potential source of tumor-derived DNA in advanced pancreatic cancer
Lapin, Morten; Tjensvoll, Kjersti; Nedrebø, Karoline; Taksdal, Eline; Janssen, Hans; Gilje, Bjørnar; Nordgård, Oddmund (Peer reviewed; Journal article, 2023)Tumor-derived extracellular vesicles (EVs) are reported to contain nucleic acids, including DNA. Several studies have highlighted the potential of EV-derived DNA (evDNA) as a circulating biomarker, even demonstrating that ...