Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Subject "kjemi"
Now showing items 1-20 of 36
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1,4-Dideoxy-1,4-imino‑D‑arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α‑Mannosidase Inhibitors
(Peer reviewed; Journal article, 2020-07)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) analogues bearing a hydrazide moiety is described. The DAB analogues act as selective and potent inhibitors of α-mannosidase ... -
3D in vitro cancer models for drug screening: A study of glucose metabolism and drug response in 2D and 3D culture models
(PhD thesis UiS;, Doctoral thesis, 2022-03)Current drug screening protocols use in vitro cancer cell panels grown in 2D to evaluate drug response and select the most promising candidates for further in vivo testing. Most drug candidates fail at this stage, not ... -
Antiscaling Evaluation and Quantum Chemical Studies of Nitrogen-Free Organophosphorus Compounds for Oilfield Scale Management
(Peer reviewed; Journal article, 2021-08)Nonpolymeric aminomethylenephosphonates are widely used as powerful scale inhibitors in the petroleum industry. However, most of these inhibitors have certain drawbacks, such as low biodegradability and incompatibilities ... -
Boronic and Organic Acids as Synergists for a Poly(N-vinylcaprolactam) Kinetic Hydrate Inhibitor
(Peer reviewed; Journal article, 2021-12)A range of boronic acids have been investigated as synergists for the kinetic hydrate inhibitor (KHI) polymer, poly(N-vinylcaprolactam) (PVCap, Mw ≈ 10,000 g/mol) using high pressure rocking cells, a natural gas mixture, ... -
Cavity Size Effects on the Adsorption of CO2 on Pillar[n]arene Structures: A Density Functional Theory Study
(Peer reviewed; Journal article, 2023-08)Carbon dioxide (CO2) is the main greenhouse gas that contributes to the global warming. Therefore, CO2 adsorption is very urgent in the fight to limit global warming below 1.5 degrees Celsius. In this report, the interaction ... -
Characterization of protein complexes and photosynthetic performance of Arabidopsis thaliana mutant plants impaired in state transition, energy-dependent non-photochemical quenching, and cyclic electron flow
(PhD thesis UiS;, Doctoral thesis, 2023)For optimal photosynthesis, the photosystem complexes in the plant leaf adapt to their light environment. In a process termed “state transition”, light energy distributes between photosystem II (PSII) and photosystem I ... -
Combined Effect of Citric Acid and Polyphenol-Rich Grape Seed Extract towards Bioactive Smart Food Packaging Systems
(Peer reviewed; Journal article, 2023-07)Alginate films (2% w·v−1) were prepared with varying concentrations (5–20% w/w) of citric acid and aqueous grape seed extract (GSE) filtrate (11.66 ± 1.32 g GAE/L) using the solvent-evaporation method. Crosslinking alginate ... -
Diastereoselectivity in Anomeric O-alkylation Glycosylation
(PhD thesis UiS;, Doctoral thesis, 2021-02)Biosynth AS used anomeric O-alkylation of α-haloacetophenones in their patented total synthesis of anthocyanins from 2006. There were, however, several challenges with stereoselectivity and yields when performing this ... -
Directed ortho-Metalation and Anionic ortho-Fries Rearrangement of Polycyclic Aromatic O-Carbamates: Regioselective Synthesis of Substituted Chrysenes
(Peer reviewed; Journal article, 2018-03)A general method for the regioselective synthesis of a series of ortho-substituted chrysenyl N,N-diethyl-O-carbamates by the directed ortho-metalation (DoM) strategy is reported. The starting O-carbamates were prepared ... -
Distinct Clades of Protein Phosphatase 2A Regulatory B’/B56 Subunits Engage in Different Physiological Processes
(Peer reviewed; Journal article, 2023-07)Protein phosphatase 2A (PP2A) is a strongly conserved and major protein phosphatase in all eukaryotes. The canonical PP2A complex consists of a catalytic (C), scaffolding (A), and regulatory (B) subunit. Plants have three ... -
Divergent Synthesis of Indolo[3,2- c]quinolines, Neocryptolepines and Related Tetracyclic Ring-Systems Containing Promising Biological Activities
(PhD thesis UiS;, Doctoral thesis, 2022)Malaria is a devastating tropical disease, claiming approximately 627 000 lives in 2020. Due to the appearance of resistance towards artemisinin-based therapies, the discovery of novel treatments are of paramount ... -
From Research to Clinical Diagnostics: Developing and Validating Biomarkers and Artificial Intelligence for Pathology
(PhD thesis UiS;, Doctoral thesis, 2024)In 2021, digital pathology was deployed in the hospitals of the western health region of Norway. Histological tissue specimens previously viewed under the microscope on glass slides, are now being scanned, and whole slide ... -
Investigation of Lactam- Based Kinetic Hydrate Inhibitors and the Synergetic Effect of Solvents
(PhD thesis UiS;, Doctoral thesis, 2022)Gas hydrate formation in flow lines is of notorious concern for the oil and gas industry, and it only gets bigger because of the never-ending pursuit of oil and gas compels the industry into deeper and colder waters. Gas ... -
Investigation of New Classes of Amide and Non-amide Kinetic Hydrate Inhibitors
(PhD thesis UiS;538, Doctoral thesis, 2020-09)The formation of gas hydrates can cause pipeline blockage during the transportation of gas and oil products, which is one of the main challenges for flow assurance in the petroleum industry. It is uneasy to remove gas ... -
Low-temperature anaerobic wastewater treatment by granulated biomass
(PhD thesis UiS;, Doctoral thesis, 2022-05)In this study, long-term operation of up-flow anaerobic sludge blanket (UASB) system treating real municipal wastewater at decreasing temperatures (25, 16, 12, 8.5, 5.5, and 2.5 °C) and variable organic loading rates from ... -
Matkjemiens rolle i å skape sunne og kritiske elever
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-12)The aim of the study was to determine the extent to which dietary education and the food chemistry in secondary schools affect the pupils' attitudes and actions in relation to diet. To find out more about this, the study ... -
Metabolic Cancer Therapy Using Graphene Drug Carriers: A study of biguanide drug effects in cellular and zebrafish larvae model systems
(PhD thesis UiS;, Doctoral thesis, 2021-11)Targeting cancer metabolism is an increasingly important strategy in the fight against cancer relapse. Metabolic drugs belonging to the biguanides family have gained attention in cancer treatment due to their ability to ... -
Microstructural Investigations of VO2 Thermochromic Thin Films Grown by Pulsed Laser Deposition for Smart Windows Applications
(Peer reviewed; Journal article, 2022)Abstract The structural properties of VO2 thin films, grown on either LSAT or Si substrates by pulsed laser deposition (PLD), are elucidated by means of transmission electron microscopy (TEM) methods. The TEM observations ... -
Model Development and Investigations on Ion Homeostasis
(PhD thesis UiS;, Doctoral thesis, 2023-05)The environment surrounding an organism, a cell and an organelle is constantly changing. To keep organisms functioning there is an everlasting need to regulate and adapt in order to keep the internal environment relatively ... -
Phosphonated Iminodisuccinates-A Calcite Scale Inhibitor with Excellent Biodegradability
(Peer reviewed; Journal article, 2023-01)Scale inhibitors are an extremely important chemical in upstream oil and gas field operations and water treatment industries. These inhibitors prevent nucleation and/or crystal growth of scales such as calcite and barite. ...