Browsing Vitenskapelige publikasjoner (TN-IKBM) by Subject "medisinsk kjemi"
Now showing items 1-2 of 2
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Design, synthesis and antitumor evaluation of novel pyrazolopyrimidines and pyrazoloquinazolines
(Journal article; Peer reviewed, 2018-05)A series of N-aryl-7-aryl-pyrazolo[1,5-a]pyrimidines 18a–u and N-aryl-pyrazolo[1,5-a] quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles 11a–c with enaminones 12a–g or 19, respectively. ... -
Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers
(Peer reviewed; Journal article, 2023-09)The copper-catalysed azide-alkyne cycloaddition was applied to prepare three enantiomeric pairs of heterodimers containing a tacrine residue and a 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) or 1,4-dideoxy-1,4-imino-L-arabinitol ...