Browsing Studentoppgaver (TN-IKBM) by Author "Alexeeva, Marina"
Now showing items 1-3 of 3
-
Excision of 5-hydroxymethyluracil in single-stranded DNA by hSMUG1 requires Ser26 and/or Glu35 and Pro240
Bærheim, Trond (Master thesis, 2021)The integrity of the genetic material of all organisms is assaulted continuously by a multitude of endogenous and exogenous agents throughout its lifetime, where the DNA bases of the genetic code may be altered if not ... -
hUNG activity for uracil in bubble and R-loop DNA
Mehanna, Shimaa (Master thesis, 2021)Uracil, a common base in RNA, may arise in cellular DNA by cytosine deamination or during replication through the misincorporation of deoxyuridine monophosphate instead of thymidine monophosphate. Repair of uracil is ... -
Uracil-excising activity of hSMUG1 in bubble and R-loop DNA
Ruales, Cyrell Ann (Master thesis, 2021)Uracil arises in cellular DNA by hydrolytic cytosine (C) deamination and by erroneous repli-cative incorporation of deoxyuridine monophosphate opposite adenine. The former event is devastating by generation of C thymine ...