Blar i UiS Brage på forfatter "Alhourani, Abdelnour H."
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Metabolic Cancer Therapy Using Graphene Drug Carriers: A study of biguanide drug effects in cellular and zebrafish larvae model systems
Alhourani, Abdelnour H. (PhD thesis UiS;, Doctoral thesis, 2021-11)Targeting cancer metabolism is an increasingly important strategy in the fight against cancer relapse. Metabolic drugs belonging to the biguanides family have gained attention in cancer treatment due to their ability to ... -
Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
Alhourani, Abdelnour H.; Tidwell, Tia R.; Bokil, Ansooya Avinash; Røsland, Gro V.; Tronstad, Karl Johan; Søreide, Kjetil; Hagland, Hanne R. (Peer reviewed; Journal article, 2021-05)Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a ...