Blar i UiS Brage på forfatter "Skadberg, Øyvind"
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Determinants of interindividual variation in exercise-induced cardiac troponin i levels
Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Eijsvogels, Thijs M. H.; Skadberg, Øyvind; Frøysa, Vidar; Wiktorski, Tomasz; Auestad, Bjørn; Edvardsen, Thor; Aakre, Kristin Moberg; Ørn, Stein (Peer reviewed; Journal article, 2021-08)Background Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 ... -
Determination of eleven steroid hormones and bioavailable testosterone in human serum using salting-out assisted liquid-liquid extraction with UHPLC-MS/MS
Ramos, Marliet (Master thesis, 2023)Steroid hormones are essential in various biological roles such as the regulation of sexual maturation, fertility, bone and muscle growth, stress-mediated responses, and inflammation, to name a few examples. Impaired ... -
Duration of elevated heart rate Is an important predictor of exercise-induced troponin elevation
Bjørkavoll-Bergseth, Magnus; Kleiven, Øyunn; Auestad, Bjørn Henrik; Eftestøl, Trygve Christian; Oskal, Kay Raymond; Nygård, Martin; Skadberg, Øyvind; Aakre, Kristin Moberg; Melberg, Tor Harald; Gjesdal, Knut; Ørn, Stein (Peer reviewed; Journal article, 2020)Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by ... -
Endurance exercise training volume is not associated with progression of coronary artery calcification
Kleiven, Øyunn; Bjørkavoll-Bergseth, Magnus; Omland, Torbjørn; Aakre, Kristin Moberg; Frøysa, Vidar; Erevik, Christine B.; Greve, Ole Jacob; Melberg, Tor Harald; Auestad, Bjørn Henrik; Skadberg, Øyvind; Edvardsen, Thor; Ørn, Stein (Peer reviewed; Journal article, 2020-02)Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ... -
Glycated albumin and continuous glucose monitoring metrics across pregnancy in women with pre-gestational diabetes
Toft, Johanne Holm; Dalen, Ingvild; Skadberg, Øyvind; Gøransson, Lasse Gunnar; Økland, Inger; Bleskestad, Inger Hjørdis (Peer reviewed; Journal article, 2022)Introduction Glycated albumin (GA), a biomarker reflecting short-term glycaemia, may be useful to assess glycaemic control in pregnancy. We examined the association between GA and continuous glucose monitoring (CGM) metrics ... -
Glycated albumin in pregnancy: LC-MS/MS-based reference interval in healthy, nulliparous Scandinavian women and its diagnostic accuracy in gestational diabetes mellitus
Toft, Johanne Holm; Bleskestad, Inger Hjørdis; Skadberg, Øyvind; Gøransson, Lasse Gunnar; Økland, Inger (Peer reviewed; Journal article, 2022-02)Glycated albumin (GA) may be a useful biomarker of glycemia in pregnancy. The aim of this study was to establish the reference interval (RI) for GA, analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS), ... -
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
Oppen, Kjersti; Brede, Cato; Skadberg, Øyvind; Steinsvik, Trude; Holter, Jan Cato; Michelsen, Annika Elisabet; Heggelund, Lars (Peer reviewed; Journal article, 2023-02)Background The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ... -
Hepcidin analysis in pneumonia: Comparison of immunoassay and LC-MS/MS
Oppen, Kjersti; Brede, Cato; Skadberg, Øyvind; Steinsvik, Trude; Holter, Jan Cato; Michelsen, Annika Elisabet; Heggelund, Lars (Peer reviewed; Journal article, 2023)Background The iron-regulatory hormone hepcidin is a promising biomarker to differentiate anaemia of inflammation from iron deficiency. Plasma hepcidin concentrations increase substantially during inflammation, and the ... -
Hepcidin and ferritin predict microbial etiology in community-acquired pneumonia
Oppen, Kjersti; Ueland, Thor; Siljan, William Ward; Skadberg, Øyvind; Brede, Cato; Lauritzen, Trine; Aukrust, Pål; Steinsvik, Trude; Husebye, Einar; Michelsen, Annika; Holter, Jan Cato; Heggelund, Lars (Peer reviewed; Journal article, 2021-02)Background Iron is crucial for survival and growth of microbes. Consequently, limiting iron availability is a human antimicrobial defense mechanism. We explored iron and iron-related proteins as potential biomarkers in ... -
Hepcidin predicts 5-year mortality after community-acquired pneumonia
Oppen, Kjersti; Ueland, Thor; Michelsen, Annika Elisabet; Aukrust, Pål; Steinsvik, Trude; Skadberg, Øyvind; Brede, Cato; Siljan, William Ward; Husebye, Einar; Holter, Jan Cato; Heggelund, Lars (Peer reviewed; Journal article, 2022)Background Virtually all living organisms, including microbes and humans, depend on iron to survive and grow. During an infection, the plasma level of iron and several iron-related proteins change substantially. We ... -
High-Sensitivity Cardiac Troponin I and T Response Following Strenuous Activity is Attenuated by Smokeless Tobacco: NEEDED (North Sea Race Endurance Exercise Study) 2014
Skranes, Julia Brox; Kleiven, Øyunn; Aakre, Kristin Moberg; Skadberg, Øyvind; Melberg, Tor Harald; Omland, Torbjørn; Ørn, Stein (Peer reviewed; Journal article, 2020)Background Use of snus, a smokeless tobacco product, is increasing in Scandinavia. Strenuous physical activity is associated with an acute increase in high‐sensitivity cardiac troponin (swhs‐cTn) concentrations. Current ... -
Occult obstructive coronary artery disease is associated with prolonged cardiac troponin elevation following strenuous exercise
Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-06)Background Sudden cardiac death among middle-aged recreational athletes is predominantly due to myocardial ischaemia. This study examined whether measuring cardiac troponin I and T (cTnI and cTnT) after strenuous exercise ... -
Race duration and blood pressure are major predictors of exercise-induced cardiac troponin elevation
Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-02)Background The underlying mechanisms of the exercise-induced increase in cardiac troponins (cTn) are poorly understood. The aim of this study was to identify independent determinants of exercise-induced cTn increase in a ... -
Regular consumption of cod liver oil is associated with reduced basal and exercise-induced C-reactive protein levels; a prospective observational trial
Hansen, Mette Wærstad; Ørn, Stein; Erevik, Christine Bjørkvik; Bjørkavoll-Bergseth, Magnus; Skadberg, Øyvind; Melberg, Tor Harald; Aakre, Kristin Moberg; Kleiven, Øyunn (Peer reviewed; Journal article, 2021-06)Background Dietary supplement use among recreational athletes is common, with the intention of reducing inflammation and improving recovery. We aimed to describe the relationship between omega-3 fatty acid supplement use ... -
The relationship between Fibroblast Growth Factor 23 (FGF23) and cardiac MRI findings following primary PCI in patients with acute first time STEMI
Thorsen, Inga Strand; Gøransson, Lasse Gunnar; Ueland, Thor; Aukrust, Pål; Manhenke, Cord A; Skadberg, Øyvind; Jonsson, Grete; Ørn, Stein (Peer reviewed; Journal article, 2021-04)Background Fibroblast growth factor 23 (FGF23) is a regulator of mineral metabolism, that has been linked to myocardial remodeling including development of left ventricular (LV) hypertrophy and myocardial fibrosis. The ... -
The relationship between workload and exercise-induced cardiac troponin elevations is influenced by non-obstructive coronary atherosclerosis
Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Wiktorski, Tomasz; Auestad, Bjørn Henrik; Skadberg, Øyvind; Aakre, Kristin Moberg; Eijsvogels, Thijs M. H.; Ørn, Stein (Peer reviewed; Journal article, 2024-05)The relationship between exercise-induced troponin elevation and non-obstructive coronary artery disease (CAD) is unclear. This observational study assessed non-obstructive CAD's impact on exercise-induced cardiac Troponin ...