Browsing UiS Brage by Author "Eikemo, Vebjørn"
Now showing items 1-4 of 4
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Evaluation of photodegradable chitin synthetase inhibitors for the treatment of salmon lice (Lepeophtheirus salmonis)
Sydnes, Magne Olav; Eikemo, Vebjørn; Espedal, Per Gunnar; Sydnes, Leiv K.; Nilsen, Frank (Peer reviewed; Journal article, 2023)Some photolabile ethanolamine analogues of the chitin synthetase inhibitors diflubenzuron, teflubenzuron, and lufenuron were tested for activity as anti-lice compounds towards salmon lice (Lepeophtheirus salmonis). Two ... -
Photodegradable antimicrobial agents - synthesis, photodegradation, and biological evaluation
Eikemo, Vebjørn; Sydnes, Leiv K.; Sydnes, Magne Olav (Peer reviewed; Journal article, 2021-09)Multi-drug resistant (MDR) bacteria are already a significant health-care problem and are making the combat of infections quite challenging. Here we report the synthesis of several new compounds containing an ethanolamine ... -
Photodegradable Antimicrobial Agents: Synthesis and Mechanism of Degradation
Eikemo, Vebjørn; Holmelid, Bjarte; Sydnes, Leiv K.; Sydnes, Magne Olav (Peer reviewed; Journal article, 2022)As a strategy to inactivate antimicrobial agents after use, we designed a range of ethanolamine derivatives where four of them possessed interesting activity. The ethanolamine moiety facilitates photodecomposition, which ... -
Synthesis and Photodecomposition Studies of Photodegradable Antibiotics and Chitin Synthase Inhibitors
Eikemo, Vebjørn (PhD thesis UiS;, Doctoral thesis, 2022-05)The release of bioactive compounds to the biosphere, such as chitin synthase inhibitors that are causing negative effects in non-target organisms, or antibiotic agents that contribute to increasing antimicrobial resistance, ...