• Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein 

      Tesfahun, Almaz Nigatu; Alexeeva, Marina; Tomkuvienė, Miglė; Arshad, Aysha; Guragain, Prashanna; Klungland, Arne; Klimašauskas, Saulius; Ruoff, Peter; Bjelland, Svein (Peer reviewed; Journal article, 2021-06)
      DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ...
    • DNA glycosylase activities for N4,5-dimethylcytosine 

      Guragain, Prashanna (Master thesis, 2017-06)
      Although the epigenetic DNA base 5-methylcytosine (m5C) has an important role in cellular functions, damaging chemical alterations to m5C have been little studied. For example, while much knowledge exists on erroneous ...