• Associations between symptom and neurocognitive dimensions in clinical high risk for psychosis 

      Aase, Ingvild; Langeveld, Johannes Hendrik; Joa, Inge; Johannessen, Jan Olav; Dalen, Ingvild; Hegelstad, Wenche (Peer reviewed; Journal article, 2022)
      Introduction Clinical high risk for psychosis (CHR) is associated with mild cognitive impairments. Symptoms are clustered into positive, negative and disorganization symptoms. The association between specific symptom ...
    • Childhood trauma, antipsychotic medication, and symptom remission in first-episode psychosis 

      Ottesen, Akiah; Hegelstad, Wenche; Joa, Inge; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Johannessen, Jan Olav; Larsen, Tor Ketil; Haahr, Ulrik H.; McGlashan, T.H.; Friis, Svein; Melle, Ingrid (Peer reviewed; Journal article, 2021-11)
      Background To what extent psychotic symptoms in first-episode psychosis (FEP) with a history of childhood interpersonal trauma (CIT) are less responsive to antipsychotic medication is not known. In this longitudinal study, ...
    • Cognitive predictors of longitudinal positive symptom course in clinical high risk for psychosis 

      Aase, Ingvild; Langeveld, Johannes Hendrik; Johannessen, Jan Olav; Joa, Inge; Dalen, Ingvild; Hegelstad, Wenche (Peer reviewed; Journal article, 2021)
      Background Clinical High Risk (CHS) for psychosis is a state in which positive symptoms are predominant but do not reach a level of severity that fulfils the criteria for a psychotic episode. The aim of this study has ...
    • COVID-19 lockdown – who cares? The first lockdown from the perspective of relatives of people with severe mental illness 

      Mork, Erlend; Aminoff, Sofie Ragnhild; Barrett, Elizabeth Ann; Simonsen, Carmen Elisabeth; Hegelstad, Wenche; Lagerberg, Trine Vik; Melle, Ingrid; Romm, Kristin Lie (Peer reviewed; Journal article, 2022)
      Background Informal care is vital to many people with severe mental illness under normal circumstances. Little is known about how extraordinary circumstances affect relatives with a family member with mental illness. This ...
    • The COVID-19 pandemic impact on wellbeing and mental health in people with psychotic and bipolar disorders 

      Barrett, Elizabeth Ann; Simonsen, Carmen Elisabeth; Aminoff, Sofie Ragnhild; Hegelstad, Wenche; Lagerberg, Trine Vik; Melle, Ingrid; Mork, Erlend; Romm, Kristin Lie (Peer reviewed; Journal article, 2022)
      Introduction The COVID-19 pandemic affects people globally, but it may affect people with psychotic and bipolar disorders disproportionally. Our aims were to investigate the pandemic impact on perceived wellbeing and ...
    • Early detection of ultra high risk for psychosis in a Norwegian catchment area: The two year follow-up of the Prevention of Psychosis study 

      Joa, Inge; Bjørnestad, Jone Ravndal; Johannessen, Jan Olav; Langeveld, Johannes Hendrik; Stain, Helen J.; Weibell, Melissa Anne Elin Authen; Hegelstad, Wenche (Peer reviewed; Journal article, 2021-02)
      Objectives: Most individuals experience a relatively long period of sub-clinical psychotic like symptoms, known as the ultra high risk (UHR) or at risk mental states (ARMS), prior to a first episode of psychosis. Approximately ...
    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Weibell, Melissa Anne E; Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Journal article; Peer reviewed, 2019-07)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...
    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Journal article; Peer reviewed, 2019-07)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...
    • "Everyone Needs a Friend Sometimes" - social predictors of long-term remission in first episode psychosis 

      Bjørnestad, Jone Ravndal; Joa, Inge; Larsen, Tor Ketil; Langeveld, Johannes H.; Davidson, Larry; Hegelstad, Wenche; Anda-Ågotnes, Liss Gøril; Veseth, Marius; Melle, Ingrid; Johannessen, Jan Olav; Brønnick, Kolbjørn Selvåg (Journal article; Peer reviewed, 2016-10)
      Background: Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social ...
    • Imminent and Short-Term Risk of Death by Suicide in 7,000 Acutely Admitted Psychiatric Inpatients 

      Fredriksen, Kristin Jørstad; Bartz-Johannessen, Christoffer; Schøyen, Helle Kristine; Vaaler, Arne; Walby, Fredrik A; Hegelstad, Wenche (Peer reviewed; Journal article, 2022)
      Objective: To prospectively investigate the predictive value of diagnosis, suicidal behavior, and subjectively experienced depressed mood for imminent risk of suicide death. Methods: This prospective study included a ...
    • Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis 

      Baldwin, Helen; Radua, Joaquim; Antoniades, Mathilde; Haas, Shalaila S.; Frangou, Sophia; Agartz, Ingrid; Allen, Paul; Andreassen, Ole; Atkinson, Kimberley; Bachman, Peter; Baeza, Inmaculada; Bartholomeusz, Cali F.; Chee, Michael W. L.; Colibazzi, Tiziano; Cooper, Rebecca E.; Corcoran, Cheryl M.; Cropley, Vanessa L.; Ebdrup, Bjørn H.; Fortea, Adriana; Glenthøj, Louise Birkedal; Hamilton, Holly K.; Haut, Kristen M.; Hayes, Rebecca A.; He, Ying; Heekeren, Karsten; Kaess, Michael; Kasai, Kiyoto; Katagiri, Naoyuki; Kim, Minah; Kindler, Jochen; Klaunig, Mallory J.; Koike, Shinsuke; Koppel, Alex; Kristensen, Tina D.; Bin Kwak, Yoo; Kwon, Jun Soo; Lawrie, Stephen M.; Lebedeva, Irina; Lee, Jimmy; Lin, Ashleigh; Loewy, Rachel L.; Mathalon, Daniel H.; Michel, Chantal; Mizrahi, Romina; Møller, Paul; Nelson, Barnaby; Nemoto, Takahiro; Nordholm, Dorte; Omelchenko, Maria A.; Pantelis, Christos; Raghava, Jayachandra M.; Røssberg, Jan Ivar; Rössler, Wulf; Salisbury, Dean F.; Sasabayashi, Daiki; Schall, Ulrich; Smigielski, Lukasz; Sugranyes, Gisela; Suzuki, Michio; Takahashi, Tsutomu; Tamnes, Christian Krog; Tang, Jinsong; Theodoridou, Anastasia; Thomopoulos, Sophia I.; Tomyshev, Alexander S.; Uhlhaas, Peter J.; Værnes, Tor Gunnar; van Amelsvoort, Therese A. M. J.; Van Erp, Theo G. M.; Waltz, James A.; Westlye, Lars Tjelta; Wood, Stephen J.; Zhou, Juan H.; McGuire, Philip; Thompson, Paul M.; Jalbrzikowski, Maria; Hernaus, Dennis; Fusar-Poli, Paolo; de la Fuente-Sandoval, Camilo; Catalano, Sabrina; Hubl, Daniela; Schiffman, Jason; Venegoni, Enea D.; Hooker, Christine I.; Rasser, Paul E.; Hegelstad, Wenche; Resch, Franz; Lemmers-Jansen, Imke L. J.; Amminger, G. Paul; Chen, Xiaogang; Cho, Kang Ik K.; Glenthøj, Birte Yding; de Haan, Lieuwe; Harris, Matthew A.; Hwang, Wu Jeong; León-Ortiz, Pablo; Ma, Xiaoqian; McGorry, Patrick; Mora-Durán, Ricardo; Mizuno, Masafumi; Nordentoft, Merete; Ouyang, Lijun; Pariente, Jose C.; Reyes-Madrigal, Francisco; Sørensen, Mikkel E.; Velakoulis, Dennis; Vinogradov, Sophia; Wenneberg, Christina; Yamasue, Hidenori; Yuan, Liu; Yung, Alison R. (Peer reviewed; Journal article, 2022)
      Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical heterogeneity in the CHR-P state is largely undetermined. ...
    • One-year outcome and adherence to pharmacological guidelines in first-episode schizophrenia: Results from a consecutive cohort study 

      Drosos, Petros; Brønnick, Kolbjørn Kallesten; Joa, Inge; Johannessen, Jan Olav; Johnsen, Erik; Kroken, Rune Andreas; Stain, Helen J.; Hegelstad, Wenche; Larsen, Tor Ketil (Peer reviewed; Journal article, 2020)
      Background Remission in schizophrenia is difficult to achieve. Antipsychotic drugs are critical in the treatment of schizophrenia. International guidelines for the pharmacological treatment of schizophrenia recommend a ...
    • Psychotherapy in psychosis: Experiences of fully recovered service users 

      Bjørnestad, Jone Ravndal; Veseth, Marius; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Hegelstad, Wenche (Journal article; Peer reviewed, 2018-09)
      Background: Despite the evidence of the importance of including service users’ views on psychotherapy after psychosis, there is a paucity of research investigating impact on full recovery. Objectives: To explore what ...
    • Reduced Expression of Emotion: A Red Flag Signalling Conversion to Psychosis in Clinical High Risk for Psychosis (CHR-P) Populations 

      Bjørnestad, Jone Ravndal; Tjora, Tore; Langeveld, Johannes Hendrik; Joa, Inge; Johannessen, Jan Olav; Friedman‐Yakoobian, Michelle; Hegelstad, Wenche (Peer reviewed; Journal article, 2022-02)
      Objective: In this hypothesis-testing study, which is based on findings from a previous atheoretical machine-learning study, we test the predictive power of baseline “reduced expression of emotion” for psychosis. Method: ...
    • Social media and social functioning in psychosis: A systematic review 

      Bjørnestad, Jone Ravndal; Hegelstad, Wenche; Berg, Henrik; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Melle, Ingrid; Stain, Helen J.; Pallesen, Ståle (Journal article; Peer reviewed, 2019-06)
      Background: Individuals with psychosis are heavy consumers of social media. It is unknown to what degree measures of social functioning include measures of online social activity. Objective: To examine the inclusion of ...
    • Views of young people with psychosis on using virtual reality assisted therapy. A qualitative study 

      Holgersen, Guri; Nordgreen, Tine; Hegelstad, Wenche; Elgen, Irene Bircow (Peer reviewed; Journal article, 2022)
      Aim Service disengagement is a challenge in young individuals struggling with psychosis. Combining cognitive behavioural therapy for psychosis (CBTp) with virtual reality (VR) has proven acceptable and potentially effective ...