• Childhood interpersonal trauma and premorbid social adjustment as predictors of symptom remission in first episode psychosis 

      Hegelstad, Wenche ten Velden; Ottesen, Akiah; Bjørnestad, Jone Ravndal; Gismervik, Kristine; Melle, Ingrid; Stain, Helen J.; Joa, Inge; Johannessen, Jan Olav (Peer reviewed; Journal article, 2021-05)
      Background Childhood interpersonal trauma (CIT) and premorbid adjustment are both associated with poor outcome in psychosis. In this study we investigate the relative impact of CIT and premorbid adjustment on symptom ...
    • Childhood trauma, antipsychotic medication, and symptom remission in first-episode psychosis 

      Ottesen, Akiah; Hegelstad, Wenche; Joa, Inge; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Johannessen, Jan Olav; Larsen, Tor Ketil; Haahr, Ulrik H.; McGlashan, T.H.; Friis, Svein; Melle, Ingrid (Peer reviewed; Journal article, 2021-11)
      Background To what extent psychotic symptoms in first-episode psychosis (FEP) with a history of childhood interpersonal trauma (CIT) are less responsive to antipsychotic medication is not known. In this longitudinal study, ...
    • COVID-19 lockdown – who cares? The first lockdown from the perspective of relatives of people with severe mental illness 

      Mork, Erlend; Aminoff, Sofie Ragnhild; Barrett, Elizabeth Ann; Simonsen, Carmen Elisabeth; Hegelstad, Wenche; Lagerberg, Trine Vik; Melle, Ingrid; Romm, Kristin Lie (Peer reviewed; Journal article, 2022)
      Background Informal care is vital to many people with severe mental illness under normal circumstances. Little is known about how extraordinary circumstances affect relatives with a family member with mental illness. This ...
    • The COVID-19 pandemic impact on wellbeing and mental health in people with psychotic and bipolar disorders 

      Barrett, Elizabeth Ann; Simonsen, Carmen Elisabeth; Aminoff, Sofie Ragnhild; Hegelstad, Wenche; Lagerberg, Trine Vik; Melle, Ingrid; Mork, Erlend; Romm, Kristin Lie (Peer reviewed; Journal article, 2022)
      Introduction The COVID-19 pandemic affects people globally, but it may affect people with psychotic and bipolar disorders disproportionally. Our aims were to investigate the pandemic impact on perceived wellbeing and ...
    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Weibell, Melissa Anne E; Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Journal article; Peer reviewed, 2019-07)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...
    • Early substance use cessation improves cognition-10 years outcome in first-episode psychosis patients 

      Johannessen, Jan Olav; Auestad, Bjørn Henrik; Bramness, Jørgen Gustav; Brønnick, Kolbjørn Kallesten; Haahr, Ulrik; Joa, Inge; Larsen, Tor Ketil; Melle, Ingrid; Ilner, Stein E. Opjordsmoen; Rund, Bjørn Rishovd; Røssberg, Jan Ivar; Simonsen, Erik; Vaglum, Per; Stain, Helen J.; Friis, Svein; Hegelstad, Wenche (Journal article; Peer reviewed, 2019-07)
      Background: Cognitive impairment may be a risk factor for, as well as a consequence of, psychosis. Non-remitting symptoms, premorbid functioning, level of education, and socioeconomic background are known correlates. A ...
    • "Everyone Needs a Friend Sometimes" - social predictors of long-term remission in first episode psychosis 

      Bjørnestad, Jone Ravndal; Joa, Inge; Larsen, Tor Ketil; Langeveld, Johannes H.; Davidson, Larry; Hegelstad, Wenche; Anda-Ågotnes, Liss Gøril; Veseth, Marius; Melle, Ingrid; Johannessen, Jan Olav; Brønnick, Kolbjørn Selvåg (Journal article; Peer reviewed, 2016-10)
      Background: Predictors of long-term symptomatic remission are crucial to the successful tailoring of treatment in first episode psychosis. There is lack of studies distinguishing the predictive effects of different social ...
    • Increased circulating IL-18 levels in severe mental disorders indicate systemic inflammasome activation 

      Szabo, Attila; O’Connell, Kevin; Ueland, Thor; Ahmed, Mashhood Sheikh; Agartz, Ingrid; Andreou, Dimitrios; Aukrust, Pål; Boye, Birgitte; Bøen, Erlend; Drange, Ole Kristian; Elvsåshagen, Torbjørn; Engh, John Abel; Hope, Sigrun; Høegh, Margrethe Collier; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Lekva, Tove; Malt, Ulrik Fredrik; Melle, Ingrid; Morken, Gunnar; Nærland, Terje; Steen, Vidar Martin; Sørensen, Kjetil; Wedervang-Resell, Kirsten; Auten Weibell, Melissa; Westlye, Lars Tjelta; Steen, Nils Eiel; Andreassen, Ole; Djurovic, Srdjan (Peer reviewed; Journal article, 2022-01)
      Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) that are part of a psychosis continuum, and dysregulated innate immune responses have been suggested to be involved in their ...
    • Psychotherapy in psychosis: Experiences of fully recovered service users 

      Bjørnestad, Jone Ravndal; Veseth, Marius; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Larsen, Tor Ketil; Melle, Ingrid; Hegelstad, Wenche (Journal article; Peer reviewed, 2018-09)
      Background: Despite the evidence of the importance of including service users’ views on psychotherapy after psychosis, there is a paucity of research investigating impact on full recovery. Objectives: To explore what ...
    • Social media and social functioning in psychosis: A systematic review 

      Bjørnestad, Jone Ravndal; Hegelstad, Wenche; Berg, Henrik; Davidson, Larry; Joa, Inge; Johannessen, Jan Olav; Melle, Ingrid; Stain, Helen J.; Pallesen, Ståle (Journal article; Peer reviewed, 2019-06)
      Background: Individuals with psychosis are heavy consumers of social media. It is unknown to what degree measures of social functioning include measures of online social activity. Objective: To examine the inclusion of ...
    • Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation 

      Sheikh, Mashhood Ahmed; O'Connell, Kevin Sean; Lekva, Tove; Szabo, Attila; Akkouh, Ibrahim Ahmed; Osete, Jordi Requena; Agartz, Ingrid; Engh, John; Andreou, Dimitrios; Boye, Birgitte; Bøen, Erlend; Elvsåshagen, Torbjørn; Hope, Sigrun; Werner, Maren Caroline Frogner; Joa, Inge; Johnsen, Erik; Kroken, Rune Andreas; Lagerberg, Trine Vik; Melle, Ingrid; Drange, Ole Kristian; Morken, Gunnar; Nærland, Terje; Sørensen, Kjetil; Vaaler, Arne; Weibell, Melissa Anne Elin Authen; Westlye, Lars Tjelta; Aukrust, Pål; Djurovic, Srdjan; Steen, Nils Eiel; Andreassen, Ole; Ueland, Thor (Peer reviewed; Journal article, 2022)
      Background Cell adhesion molecules (CAMs) orchestrate leukocyte trafficking and could link peripheral and neuroinflammation in patients with severe mental illness (SMI), by promoting inflammatory and immune-mediated ...