Browsing UiS Brage by Author "Sandnes, Dagny Ann"

Now showing items 1-2 of 2

    • Early Forms of α-Synuclein Pathology Are Associated with Neuronal Complex I Deficiency in the Substantia Nigra of Individuals with Parkinson’s Disease 

      Flønes, Irene Hana; Nyland, Harald Inge; Sandnes, Dagny Ann; Alves, Guido Werner; Tysnes, Ole-Bjørn; Tzoulis, Charalampos (Peer reviewed; Journal article, 2022)
      Idiopathic Parkinson’s disease (iPD) is characterized by degeneration of the dopaminergic substantia nigra pars compacta (SNc), typically in the presence of Lewy pathology (LP) and mitochondrial respiratory complex I (CI) ...

    • Mitochondrial complex I deficiency stratifies idiopathic Parkinson’s disease 

      Flønes, Irene; Toker, Lilah; Sandnes, Dagny Ann; Castelli, Martina Galatea; Mostafavi, Sepideh; Lura, Njål; Shadad, Omnia; Fernandez-Vizarra, Erika; Painous, Cèlia; Pérez-Soriano, Alexandra; Compta, Yaroslau; Molina-Porcel, Laura; Alves, Guido Werner; Tysnes, Ole-Bjørn; Dölle, Christian; Sanchez Nido, Gonzalo; Tzoulis, Charalampos (Peer reviewed; Journal article, 2024)
      Idiopathic Parkinson’s disease (iPD) is believed to have a heterogeneous pathophysiology, but molecular disease subtypes have not been identified. Here, we show that iPD can be stratified according to the severity of ...