• A Longitudinal Study of Neurocognition in Dementia with Lewy Bodies Compared to Alzheimer`s Disease 

      Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Hynninen, Kia Minna; Brønnick, Kolbjørn Selvåg; Auestad, Bjørn Henrik; Aarsland, Dag; Rongve, Arvid (Journal article; Peer reviewed, 2018-03)
      Introduction: There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal ...
    • A systematic review of cognitive decline in dementia with Lewy bodies versus Alzheimer’s disease 

      Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Hynninen, Kia Minna; Rongve, Arvid; Brønnick, Kolbjørn S; Janvin, Carmen Cristea; Aarsland, Dag (Journal article; Peer reviewed, 2014-09)
      Introduction: The aim of this review was to investigate whether there is a faster cognitive decline in dementia with Lewy bodies (DLB) than in Alzheimer’s disease (AD) over time. Methods: PsycINFO and Medline were ...
    • Association Between Amygdala Volume and Trajectories of Neuropsychiatric Symptoms in Alzheimer’s Disease and Dementia With Lewy Bodies 

      Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Tovar-Rios, Diego Alejandro; Borda, Miguel Germán; Ferreira, Daniel; Brønnick, Kolbjørn Kallesten; Oppedal, Ketil; Aarsland, Dag (Peer reviewed; Journal article, 2021-07)
      Introduction: The amygdala is implicated in psychiatric illness. Even as the amygdala undergoes significant atrophy in mild dementia, amygdala volume is underexplored as a risk factor for neuropsychiatric symptoms ...
    • Association between physical activity and cognition in Mexican and Korean older adults 

      Aarsland, Vera; Borda, Miguel Germán; Aarsland, Dag; Anderssen, Sigmund Alfred (Peer reviewed; Journal article, 2020-04)
      Introduction: As the world's population ages, the prevalence of cognitive impairment associated with age in- creases. This increase is particularly pronounced in Asia and South-America. The objective of this study was to ...
    • Body mass index trajectories and associations with cognitive decline in people with Lewy body dementia and Alzheimer's disease 

      Borda, Miguel Germán; Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Tovar-Rios, Diego Alejandro; Sønnesyn, Hogne; Aarsland, Dag (Peer reviewed; Journal article, 2022)
      Background and Aims In older adults with dementia, low body mass index (BMI) is associated with higher mortality and other adverse health outcomes. BMI or nutritional status trajectories from diagnosis have not yet been ...
    • Body mass index, performance on activities of daily living and cognition: analysis in two different populations 

      Borda, Miguel Germán; Venegas-Sanabria, Luis Carlos; Garcia-Cifuentes, Elkin; Gomez, Ronald Camilo; Cano-Gutierrez, Carlos Alberto; Tovar-Rios, Diego Alejandro; Aarsland, Vera Vårin Birkemo; Khalifa, Khadija; Jaramillo-Jiménez, Alberto; Aarsland, Dag; Sønnesyn, Hogne (Peer reviewed; Journal article, 2021)
      Background With this study, we aim to determine the associations of the different categories of the body mass index (BMI) with activities of daily living (ADL) and cognitive performance in two different populations living ...
    • Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia 

      Gonzalez Velez, Maria Camila; Tovar-Rios, Diego Alejandro; Alves, Guido Werner; Dalen, Ingvild; Williams-Gray, Caroline H.; Camacho, Marta; Forsgren, Lars; Bäckström, David; Lawson, Rachael A.; Macleod, Angus D.; Counsell, Carl E.; Paquet, Claire; DeLena, Carlo; D'Antonio, Fabrizia; Pilotto, Andrea; Padovani, Alessandro; Blanc, Frédéric; Falup-Pecurariu, Cristian; Lewis, Simon J.G.; Rejdak, Konrad; Papuc, Ewa; Hort, Jakub; Nedelska, Zuzana; O'Brien, John; Bonanni, Laura; Marquié, Marta; Boada, Mercè; Pytel, Vanesa; Abdelnour, Carla; Alcolea, Daniel; Beyer, Katrin; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi (Peer reviewed; Journal article, 2023)
      Background There is a need to better understand the rate of cognitive and motor decline of Dementia with Lewy bodies (DLB) and Parkinson's disease Dementia (PDD). Objectives To compare the rate of cognitive and motor ...
    • Combinatory microRNA serum signatures as classifiers of Parkinson's disease 

      Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Journal article; Peer reviewed, 2019-04)
      As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ...
    • The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies 

      Abdelnour, Carla; Ferreira, Daniel; Oppedal, Ketil; Cavallin, Lena; Bousiges, Olivier; Wahlund, Lars Olof; Hort, Jakub; Nedelska, Zuzana; Padovani, Alessandro; Pilotto, Andrea; Bonanni, Laura; Kramberger, Milica Gregoric; Boada, Mercè; Westman, Eric; Pagonabarraga, Javier; Kulisevsky, Jaime; Blanc, Frédéric; Aarsland, Dag (Peer reviewed; Journal article, 2020-07)
      Background Alzheimer’s disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in ...
    • The course of depressive symptoms in Lewy body dementia and Alzheimer's disease 

      Römer, Benedikt Carl Gustav; Dalen, Ingvild; Ballard, Clive; Aarsland, Dag (Peer reviewed; Journal article, 2023)
      Background Depressive symptoms frequently affect patients with neurocognitive disorders. In cross-sectional studies, patients with Lewy body dementia (DLB) showed higher levels of depressive symptoms than those with ...
    • Dementia with Lewy Bodies Drug Therapies in Clinical Trials: Systematic Review up to 2022 

      Abdelnour, Carla; Gonzalez Velez, Maria Camila; Gibson, Lucy L.; Poston, Kathleen L.; Ballard, Clive; Cummings, Jeffrey L.; Aarsland, Dag (Peer reviewed; Journal article, 2023)
      Introduction Reviews of randomized clinical trials (RCTs) in dementia with Lewy bodies (DLB) are essential for informing ongoing research efforts of symptomatic therapies and potentially disease-modifying therapies ...
    • Dementia with Lewy bodies research consortia: A global perspective from the ISTAART Lewy Body Dementias Professional Interest Area working group 

      D'Antonio, Fabrizia; Kane, Joseph P. M.; Ibañez, Agustin; Lewis, Simon J. G.; Camicioli, Richard; Wang, Huali; Yu, Yueyi; Zhang, Jing; Ji, Yong; Borda, Miguel Germán; Kandadai, Rukmini Mridula; Babiloni, Claudio; Bonnani, Laura; Ikeda, Manabu; Boeve, Bradley F.; Leverenz, James B.; Aarsland, Dag (Peer reviewed; Journal article, 2021-09)
      Dementia with Lewy bodies (DLB) research has seen a significant growth in international collaboration over the last three decades. However, researchers face a challenge in identifying large and diverse samples capable of ...
    • Effects of purified anthocyanins in people at risk for dementia: Study protocol for a phase II randomized controlled trial 

      Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Oesterhus, Ragnhild; Dalen, Ingvild; Larsen, Alf Inge; Fladby, Tormod; Brooker, Helen; Wesnes, Keith A.; Ballard, Clive; Aarsland, Dag (Peer reviewed; Journal article, 2020)
      Background: The number of people with dementia is increasing, with huge challenges for society and health-care systems. There are no disease-modifying therapies available. There is, therefore, an urgent need to identify ...
    • Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19 

      Owens, Andrew P.; Ballard, Clive; Beigi, Mazda; Kalafatis, Chris; Brooker, Helen; Lavelle, Grace; Brønnick, Kolbjørn Kallesten; Sauer, Justin; Boddington, Steve; Velayudhan, Latha; Aarsland, Dag (Peer reviewed; Journal article, 2020)
      Social isolation is likely to be recommended for older adults due to COVID-19, with ongoing reduced clinical contact suggested for this population. This has increased the need for remote memory clinics, we therefore review ...
    • Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia 

      Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019-09)
      Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ...
    • Male caregivers to persons diagnosed with Lewy Body Dementia have higher stress level than caregiver to persons diagnosed with Alzheimers Dementia 

      Svendsbø, Ellen J; Terum, Toril; Testad, Ingelin; Aarsland, Dag; Rongve, Arvid (Conference object, 2015)
    • MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies 

      Inguanzo, Anna; Poulakis, Konstantinos; Mohanty, Rosaleena; Schwarz, Christopher G.; Przybelski, Scott A.; Diaz-Galvan, Patricia; Lowe, Val J.; Boeve, Bradley F.; Lemstra, Afina W.; van de Beek, Marleen; van der Flier, Wiesje; Barkhof, Frederik; Blanc, Frederic; Loureiro de Sousa, Paulo; Philippi, Nathalie; Cretin, Benjamin; Demuynck, Catherine; Nedelska, Zuzana; Hort, Jakub; Segura, Barbara; Junque, Carme; Oppedal, Ketil; Aarsland, Dag; Westman, Eric; Kantarci, Kejal; Ferreira, Daniel (Peer reviewed; Journal article, 2023)
      Dementia with Lewy bodies (DLB) is a neurodegenerative disorder with a wide heterogeneity of symptoms, which suggests the existence of different subtypes. We used data-driven analysis of magnetic resonance imaging (MRI) ...
    • Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data 

      Abdelnour, Carla; Ferreira, Daniel; van de Beek, Marleen; Cedres, Nira; Oppedal, Ketil; Cavallin, Lena; Blanc, Frédéric; Bousiges, Olivier; Wahlund, Lars-Olof; Pilotto, Andrea; Padovani, Alessandro; Boada, Mercè; Pagonabarraga, Javier; Kulisevsky, Jaime; Aarsland, Dag; Lemstra, Afina W.; Westman, Eric (Peer reviewed; Journal article, 2022)
      Background Dementia with Lewy bodies (DLB) includes various core clinical features that result in different phenotypes. In addition, Alzheimer’s disease (AD) and cerebrovascular pathologies are common in DLB. All this ...
    • A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia 

      Aarsland, Dag; Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Holteng, Lise Birgitte Austbø; Oesterhus, Ragnhild; Nakling, Arne; Jarholm, Jonas Alexander; de Lucia, Chiara; Fladby, Tormod; Brooker, Helen; Dalen, Ingvild; Ballard, Clive (Peer reviewed; Journal article, 2022)
      Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ...
    • Self-reported sleep fragmentation and sleep duration and their association with cognitive function in PROTECT, a large digital community-based cohort of people over 50 

      Aakre, Jon Arild; Schulz, Jörn; Ballard, Clive; Corbett, Anne; Bjorvatn, Bjørn; Aarsland, Dag; Creese, Byron; Hampshire, Adam; Brooker, Helen; Testad, Ingelin (Peer reviewed; Journal article, 2023)
      Objective Sleep is vital for normal cognitive function in daily life, but is commonly disrupted in older adults. Poor sleep can be detrimental to mental and physical health, including cognitive function. This study assessed ...