Blar i Publikasjoner fra CRIStin på tidsskrift "Nature Communications"

Viser treff 1-5 av 5

    • Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease 

      Dölle, Christian; Flønes, Irene Hana; Sanchez Nido, Gonzalo; Miletic, Hrvoje; Osuagwu, Nelson; Kristoffersen, Stine; Lilleng, Peer Kåre; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Bindoff, Laurence; Tzoulis, Charalampos (Journal article; Peer reviewed, 2016-11)
      Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we ...

    • Defective mitochondrial DNA homeostasis in the substantia nigra in Parkinson disease 

      Dölle, Christian; Flønes, Irene Hana; Sanchez Nido, Gonzalo; Miletic, Hrvoje; Osuagwu, Nelson; Kristoffersen, Stine; Lilleng, Peer Kåre; Larsen, Jan Petter; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Bindoff, Laurence; Tzoulis, Charalampos (Journal article; Peer reviewed, 2016-11)
      Increased somatic mitochondrial DNA (mtDNA) mutagenesis causes premature aging in mice, and mtDNA damage accumulates in the human brain with aging and neurodegenerative disorders such as Parkinson disease (PD). Here, we ...

    • Downregulation of N-terminal acetylation triggers ABA-mediated drought responses in Arabidopsis 

      Linster, Eric; Stephan, Iwona; Bienvenut, Willy V.; Maple-Grødem, Jodi; Myklebust, Line Merethe; Huber, Monika; Reichelt, Michael; Sticht, Carsten; Møller, Simon Geir; Meinnel, Thierry; Arnesen, Thomas; Giglione, Carmela; Hell, Rüdiger; Wirtz, Markus (Journal article; Peer reviewed, 2015-07)
      N-terminal acetylation (NTA) catalysed by N-terminal acetyltransferases (Nats) is among the most common protein modifications in eukaryotes, but its significance is still enigmatic. Here we characterize the plant NatA ...

    • Estimating diagnostic uncertainty in artificial intelligence assisted pathology using conformal prediction 

      Olsson, Henrik; Kartasalo, Kimmo; Mulliqi, Nita; Capuccini, Marco; Ruusuvuori, Pekka; Samaratunga, Hemamali; Delahunt, Brett; Lindskog, Cecilia; Janssen, Emiel; Blilie, Anders; Egevad, Lars; Spjuth, Ola; Eklund, Martin (Peer reviewed; Journal article, 2022)
      Unreliable predictions can occur when an artificial intelligence (AI) system is presented with data it has not been exposed to during training. We demonstrate the use of conformal prediction to detect unreliable predictions, ...

    • Neolithic culinary traditions revealed by cereal, milk and meat lipids in pottery from Scottish crannogs 

      Hammann, S.; Bishop, Rosie Rhiannon; Copper, M.; Garrow, D.; Greenwood, C.; Hewson, L.; Sheridan, S.; Sturt, F.; Whelton, H. L.; Cramp, L. J. E. (Peer reviewed; Journal article, 2022)
      Cereal cultivation in Britain dates back to ca. 4000 BCE, probably introduced by migrant farmers from continental Europe. Widespread evidence for livestock appears in the archaeozoological record, also reflected by ubiquitous ...