Browsing Vitenskapelige publikasjoner (HV) by Author "Aarsland, Dag"
Now showing items 1-20 of 23
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A Longitudinal Study of Neurocognition in Dementia with Lewy Bodies Compared to Alzheimer`s Disease
Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Hynninen, Kia Minna; Brønnick, Kolbjørn Selvåg; Auestad, Bjørn Henrik; Aarsland, Dag; Rongve, Arvid (Journal article; Peer reviewed, 2018-03)Introduction: There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal ... -
Association Between Amygdala Volume and Trajectories of Neuropsychiatric Symptoms in Alzheimer’s Disease and Dementia With Lewy Bodies
Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Tovar-Rios, Diego Alejandro; Borda, Miguel Germán; Ferreira, Daniel; Brønnick, Kolbjørn Kallesten; Oppedal, Ketil; Aarsland, Dag (Peer reviewed; Journal article, 2021-07)Introduction: The amygdala is implicated in psychiatric illness. Even as the amygdala undergoes significant atrophy in mild dementia, amygdala volume is underexplored as a risk factor for neuropsychiatric symptoms ... -
Association between physical activity and cognition in Mexican and Korean older adults
Aarsland, Vera; Borda, Miguel Germán; Aarsland, Dag; Anderssen, Sigmund Alfred (Peer reviewed; Journal article, 2020-04)Introduction: As the world's population ages, the prevalence of cognitive impairment associated with age in- creases. This increase is particularly pronounced in Asia and South-America. The objective of this study was to ... -
Body mass index trajectories and associations with cognitive decline in people with Lewy body dementia and Alzheimer's disease
Borda, Miguel Germán; Jaramillo-Jiménez, Alberto; Melvær, Giil Lasse; Tovar-Rios, Diego Alejandro; Sønnesyn, Hogne; Aarsland, Dag (Peer reviewed; Journal article, 2022)Background and Aims In older adults with dementia, low body mass index (BMI) is associated with higher mortality and other adverse health outcomes. BMI or nutritional status trajectories from diagnosis have not yet been ... -
Body mass index, performance on activities of daily living and cognition: analysis in two different populations
Borda, Miguel Germán; Venegas-Sanabria, Luis Carlos; Garcia-Cifuentes, Elkin; Gomez, Ronald Camilo; Cano-Gutierrez, Carlos Alberto; Tovar-Rios, Diego Alejandro; Aarsland, Vera Vårin Birkemo; Khalifa, Khadija; Jaramillo-Jiménez, Alberto; Aarsland, Dag; Sønnesyn, Hogne (Peer reviewed; Journal article, 2021)Background With this study, we aim to determine the associations of the different categories of the body mass index (BMI) with activities of daily living (ADL) and cognitive performance in two different populations living ... -
Cognitive and Motor Decline in Dementia with Lewy Bodies and Parkinson's Disease Dementia
Gonzalez Velez, Maria Camila; Tovar-Rios, Diego Alejandro; Alves, Guido Werner; Dalen, Ingvild; Williams-Gray, Caroline H.; Camacho, Marta; Forsgren, Lars; Bäckström, David; Lawson, Rachael A.; Macleod, Angus D.; Counsell, Carl E.; Paquet, Claire; DeLena, Carlo; D'Antonio, Fabrizia; Pilotto, Andrea; Padovani, Alessandro; Blanc, Frédéric; Falup-Pecurariu, Cristian; Lewis, Simon J.G.; Rejdak, Konrad; Papuc, Ewa; Hort, Jakub; Nedelska, Zuzana; O'Brien, John; Bonanni, Laura; Marquié, Marta; Boada, Mercè; Pytel, Vanesa; Abdelnour, Carla; Alcolea, Daniel; Beyer, Katrin; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi (Peer reviewed; Journal article, 2023)Background There is a need to better understand the rate of cognitive and motor decline of Dementia with Lewy bodies (DLB) and Parkinson's disease Dementia (PDD). Objectives To compare the rate of cognitive and motor ... -
Combinatory microRNA serum signatures as classifiers of Parkinson's disease
Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Journal article; Peer reviewed, 2019-04)As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ... -
The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies
Abdelnour, Carla; Ferreira, Daniel; Oppedal, Ketil; Cavallin, Lena; Bousiges, Olivier; Wahlund, Lars Olof; Hort, Jakub; Nedelska, Zuzana; Padovani, Alessandro; Pilotto, Andrea; Bonanni, Laura; Kramberger, Milica Gregoric; Boada, Mercè; Westman, Eric; Pagonabarraga, Javier; Kulisevsky, Jaime; Blanc, Frédéric; Aarsland, Dag (Peer reviewed; Journal article, 2020-07)Background Alzheimer’s disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in ... -
The course of depressive symptoms in Lewy body dementia and Alzheimer's disease
Römer, Benedikt Carl Gustav; Dalen, Ingvild; Ballard, Clive; Aarsland, Dag (Peer reviewed; Journal article, 2023)Background Depressive symptoms frequently affect patients with neurocognitive disorders. In cross-sectional studies, patients with Lewy body dementia (DLB) showed higher levels of depressive symptoms than those with ... -
Dementia with Lewy Bodies Drug Therapies in Clinical Trials: Systematic Review up to 2022
Abdelnour, Carla; Gonzalez Velez, Maria Camila; Gibson, Lucy L.; Poston, Kathleen L.; Ballard, Clive; Cummings, Jeffrey L.; Aarsland, Dag (Peer reviewed; Journal article, 2023)Introduction Reviews of randomized clinical trials (RCTs) in dementia with Lewy bodies (DLB) are essential for informing ongoing research efforts of symptomatic therapies and potentially disease-modifying therapies ... -
Dementia with Lewy bodies research consortia: A global perspective from the ISTAART Lewy Body Dementias Professional Interest Area working group
D'Antonio, Fabrizia; Kane, Joseph P. M.; Ibañez, Agustin; Lewis, Simon J. G.; Camicioli, Richard; Wang, Huali; Yu, Yueyi; Zhang, Jing; Ji, Yong; Borda, Miguel Germán; Kandadai, Rukmini Mridula; Babiloni, Claudio; Bonnani, Laura; Ikeda, Manabu; Boeve, Bradley F.; Leverenz, James B.; Aarsland, Dag (Peer reviewed; Journal article, 2021-09)Dementia with Lewy bodies (DLB) research has seen a significant growth in international collaboration over the last three decades. However, researchers face a challenge in identifying large and diverse samples capable of ... -
Genetic associations with psychosis and affective disturbance in Alzheimer's disease
Antonsdottir, Inga Margaret; Creese, Byron; Klei, Lambertus; DeMichele-Sweet, Mary Ann A.; Weamer, Elise A.; Garcia-Gonzalez, Pablo; Marquié, Marta; Boada, Mercé; Alarcón-Martín, Emilio; Valero, Sergi; Liu, Yushi; Hooli, Basavaraj; Aarsland, Dag; Selbæk, Geir; Bergh, Sverre; Rongve, Arvid; Saltvedt, Ingvild Tina; Skjellegrind, Håvard Kjesbu; Engdahl, Bo Lars; Andreassen, Ole; Borroni, Barbara; Mecocci, Patrizia; Wedatilake, Yehani; Mayeux, Richard; Foroud, Tatiana M.; Ruiz, Agustin; Lopez, Oscar L.; Kamboh, M. Ilyas; Ballard, Clive; Devlin, Bernie; Lyketsos, Constantine; Sweet, Robert A. (Peer reviewed; Journal article, 2024)INTRODUCTION Individuals with Alzheimer's disease (AD) commonly experience neuropsychiatric symptoms of psychosis (AD+P) and/or affective disturbance (depression, anxiety, and/or irritability, AD+A). This study's goal was ... -
Implementing Remote Memory Clinics to Enhance Clinical Care During and After COVID-19
Owens, Andrew P.; Ballard, Clive; Beigi, Mazda; Kalafatis, Chris; Brooker, Helen; Lavelle, Grace; Brønnick, Kolbjørn Kallesten; Sauer, Justin; Boddington, Steve; Velayudhan, Latha; Aarsland, Dag (Peer reviewed; Journal article, 2020)Social isolation is likely to be recommended for older adults due to COVID-19, with ongoing reduced clinical contact suggested for this population. This has increased the need for remote memory clinics, we therefore review ... -
Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia
Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019-09)Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ... -
Male caregivers to persons diagnosed with Lewy Body Dementia have higher stress level than caregiver to persons diagnosed with Alzheimers Dementia
Svendsbø, Ellen J; Terum, Toril; Testad, Ingelin; Aarsland, Dag; Rongve, Arvid (Conference object, 2015) -
A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia
Aarsland, Dag; Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Holteng, Lise Birgitte Austbø; Oesterhus, Ragnhild; Nakling, Arne; Jarholm, Jonas Alexander; de Lucia, Chiara; Fladby, Tormod; Brooker, Helen; Dalen, Ingvild; Ballard, Clive (Peer reviewed; Journal article, 2022)Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ... -
Sex differences in brain atrophy in dementia with Lewy bodies
Oltra, Javier; Habich, Annegret; Schwarz, Christopher G.; Nedelska, Zuzana; Przybelski, Scott A.; Inguanzo, Anna; Diaz-Galvan, Patricia; Lowe, Val J.; Oppedal, Ketil; Gonzalez Velez, Maria Camila; Philippi, Nathalie; Blanc, Frederic; Barkhof, Frederik; Lemstra, Afina W.; Hort, Jakub; Padovani, Alessandro; Rektorova, Irena; Bonanni, Laura; Massa, Federico; Kramberger, Milica G.; Taylor, John-Paul; Snædal, Jon G.; Walker, Zuzana; Antonini, Angelo; Dierks, Thomas; Segura, Barbara; Junque, Carme; Westman, Eric; Boeve, Bradley F.; Aarsland, Dag; Kantarci, Kejal; Ferreira, Daniel (Peer reviewed; Journal article, 2023)INTRODUCTION Sex influences neurodegeneration, but it has been poorly investigated in dementia with Lewy bodies (DLB). We investigated sex differences in brain atrophy in DLB using magnetic resonance imaging (MRI). METHODS We ... -
Specific depressive symptoms are related with different patterns of alcohol use in community-dwelling older adults
Castellanos-Perilla, Nicolás; Borda, Miguel Germán; Cataño, Sara; Giraldo, Salomon; Vik-Mo, Audun Osland; Aarsland, Dag; Rao, Rahul Tony (Peer reviewed; Journal article, 2022)Objectives To explore how individual depressive symptoms might contribute to different patterns of alcohol consumption in Colombian older adults living in the community. Methods A Secondary analysis from a nationally ... -
Spectral features of resting-state EEG in Parkinson's Disease: A multicenter study using functional data analysis
Jaramillo-Jimenez, Alberto; Tovar-Rios, Diego Alejandro; Ospina, Johann Alexis; Mantilla-Ramos, Yorguin-Jose; Loaiza-López, Daniel; Henao Isaza, Verónica; Zapata Saldarriaga, Luisa María; Cadavid Castro, Valeria; Suarez-Revelo, Jazmin Ximena; Bocanegra, Yamile; Lopera, Francisco; Pineda-Salazar, David Antonio; Tobón Quintero, Carlos Andrés; Ochoa-Gomez, John Fredy; Borda, Miguel Germán; Aarsland, Dag; Bonanni, Laura; Brønnick, Kolbjørn Kallesten (Peer reviewed; Journal article, 2023)Objective This study aims 1) To analyse differences in resting-state electroencephalogram (rs-EEG) spectral features of Parkinson's Disease (PD) and healthy subjects (non-PD) using Functional Data Analysis (FDA) and 2) ... -
The value of cerebrospinal fluid alpha-synuclein and the tau/alpha-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology
Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2019-07)Background and purpose Parkinson's disease (PD), dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are three of the most common neurodegenerative disorders. Up to 20% of these patients have the wrong diagnosis, ...