dc.contributor.author | Lorentzen, Marianne | |
dc.contributor.author | Sydnes, Magne Olav | |
dc.contributor.author | Jørgensen, Kåre Bredeli | |
dc.date.accessioned | 2021-05-04T19:00:51Z | |
dc.date.available | 2021-05-04T19:00:51Z | |
dc.date.created | 2014-12-10T13:27:51Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Lorentzen, M., Sydnes, M.O., Jørgensen, K.B. (2014) Enantioselective synthesis of (-)-(1R,2R)-1,2-dihydrochrysene-1,2-diol. Tetrahedron, 70 (47), pp. 9041-9051. | en_US |
dc.identifier.issn | 0040-4020 | |
dc.identifier.uri | https://hdl.handle.net/11250/2753575 | |
dc.description.abstract | A general chiral building block containing the 1R,2R-trans-diol moiety was constructed utilizing the stereoselective Shi-epoxidation reaction on a tetralone scaffold assembled by a Negishi cross-coupling on N,N-diethylbenzamide. Further elaboration of this chiral building block into polycyclic aromatic compounds was demonstrated with the total synthesis of the precursor for the most carcinogenic metabolite of chrysene, (−)-(1R,2R)-1,2-dihydrochrysene-1,2-diol in 87% ee. | en_US |
dc.language.iso | eng | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.subject | organisk kjemi | en_US |
dc.title | Enantioselective synthesis of (-)-(1R,2R)-1,2-dihydrochrysene-1,2-diol | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | acceptedVersion | en_US |
dc.rights.holder | Copyright © 2014 Elsevier Ltd. All rights reserved. | en_US |
dc.subject.nsi | VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440::Organisk kjemi: 441 | en_US |
dc.source.pagenumber | 9041-9051 | en_US |
dc.source.volume | 70 | en_US |
dc.source.journal | Tetrahedron | en_US |
dc.source.issue | 47 | en_US |
dc.identifier.doi | 10.1016/j.tet.2014.10.016 | |
dc.identifier.cristin | 1183497 | |
cristin.ispublished | true | |
cristin.fulltext | postprint | |
cristin.qualitycode | 1 | |