Browsing UiS Brage by Author "Kvivik, Ingeborg"
Now showing items 1-7 of 7
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Anti-HMGB1 auto-Abs influence fatigue in patients with Crohn’s disease
Kvivik, Ingeborg; Grimstad, Tore Bjørn; Jonsson, Grete; Kvaløy, Jan T.; Omdal, Roald (Peer reviewed; Journal article, 2021-05)Fatigue is common in all chronic inflammatory and autoimmune diseases. A conceptual model for understanding the biological basis of fatigue describes it as being a part of the sickness behaviour response generated by ... -
Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease
Grimstad, Tore; Kvivik, Ingeborg; Kvaløy, Jan Terje; Aabakken, Lars; Omdal, Roald (Journal article; Peer reviewed, 2019-10)Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ... -
High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn’s disease
Kvivik, Ingeborg; Grimstad, Tore Bjørn; Bårdsen, Kjetil; Jonsson, Grete; Kvaløy, Jan Terje; Omdal, Roald (Peer reviewed; Journal article, 2023-06)Background Fatigue is common in patients with chronic inflammatory and autoimmune diseases, often with a severe impact on the patient’s daily life. From a biological point of view, fatigue can be regarded as an element ... -
High mobility group box 1 in human serum - investigation of different analysis methods and possible associations with disease activity and fatigue in patients with systemic lupus erythematosus
Kvivik, Ingeborg (Masteroppgave/UIS-TN-IMN/2012;, Master thesis, 2012)The High mobility group box 1 (HMGB1) protein is a DNA-binding protein mainly located in the nucleus of cells. It can be passively or actively released to the extracellular environment in necrotic cells or activated cells ... -
Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren's syndrome
Bårdsen, Kjetil; Brede, Cato; Kvivik, Ingeborg; Kvaløy, Jan Terje; Jonsdottir, Kristin; Tjensvoll, Anne Bolette; Ruoff, Peter; Omdal, Roald (Peer reviewed; Journal article, 2019)Background Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide ... -
Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren’s syndrome
Tjensvoll, Anne Bolette; Lauvsnes, Maria Boge; Zetterberg, Henrik; Kvaløy, Jan Terje; Kvivik, Ingeborg; Maroni, Stian; Greve, Ole Jacob; Beyer, Mona K.; Hirohata, Shunsei; Putterman, Chaim; Alves, Guido Werner; Harboe, Erna; Blennow, Kaj; Gøransson, Lasse; Omdal, Roald (Peer reviewed; Journal article, 2020-10)Background To test the hypothesis that neurofilament light (NfL) in CSF is a biomarker of CNS involvement in patients with systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS), we measured NfL in CSF ... -
Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein
Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato (Peer reviewed; Journal article, 2021-06)Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...