• Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data 

      Abdelnour, Carla; Ferreira, Daniel; van de Beek, Marleen; Cedres, Nira; Oppedal, Ketil; Cavallin, Lena; Blanc, Frédéric; Bousiges, Olivier; Wahlund, Lars-Olof; Pilotto, Andrea; Padovani, Alessandro; Boada, Mercè; Pagonabarraga, Javier; Kulisevsky, Jaime; Aarsland, Dag; Lemstra, Afina W.; Westman, Eric (Peer reviewed; Journal article, 2022)
      Background Dementia with Lewy bodies (DLB) includes various core clinical features that result in different phenotypes. In addition, Alzheimer’s disease (AD) and cerebrovascular pathologies are common in DLB. All this ...
    • A Randomised Placebo-Controlled Study of Purified Anthocyanins on Cognition in Individuals at Increased Risk for Dementia 

      Aarsland, Dag; Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Holteng, Lise Birgitte Austbø; Oesterhus, Ragnhild; Nakling, Arne; Jarholm, Jonas Alexander; de Lucia, Chiara; Fladby, Tormod; Brooker, Helen; Dalen, Ingvild; Ballard, Clive (Peer reviewed; Journal article, 2022)
      Importance Identifying nutritional compounds which can reduce cognitive decline in older people is a hugely important topic. Objective To study the safety and effect of anthocyanins in maintaining cognitive functioning ...
    • Self-reported sleep fragmentation and sleep duration and their association with cognitive function in PROTECT, a large digital community-based cohort of people over 50 

      Aakre, Jon Arild; Schulz, Jörn; Ballard, Clive; Corbett, Anne; Bjorvatn, Bjørn; Aarsland, Dag; Creese, Byron; Hampshire, Adam; Brooker, Helen; Testad, Ingelin (Peer reviewed; Journal article, 2023)
      Objective Sleep is vital for normal cognitive function in daily life, but is commonly disrupted in older adults. Poor sleep can be detrimental to mental and physical health, including cognitive function. This study assessed ...
    • Sex differences in brain atrophy in dementia with Lewy bodies 

      Oltra, Javier; Habich, Annegret; Schwarz, Christopher G.; Nedelska, Zuzana; Przybelski, Scott A.; Inguanzo, Anna; Diaz-Galvan, Patricia; Lowe, Val J.; Oppedal, Ketil; Gonzalez Velez, Maria Camila; Philippi, Nathalie; Blanc, Frederic; Barkhof, Frederik; Lemstra, Afina W.; Hort, Jakub; Padovani, Alessandro; Rektorova, Irena; Bonanni, Laura; Massa, Federico; Kramberger, Milica G.; Taylor, John-Paul; Snædal, Jon G.; Walker, Zuzana; Antonini, Angelo; Dierks, Thomas; Segura, Barbara; Junque, Carme; Westman, Eric; Boeve, Bradley F.; Aarsland, Dag; Kantarci, Kejal; Ferreira, Daniel (Peer reviewed; Journal article, 2023)
      INTRODUCTION Sex influences neurodegeneration, but it has been poorly investigated in dementia with Lewy bodies (DLB). We investigated sex differences in brain atrophy in DLB using magnetic resonance imaging (MRI). METHODS We ...
    • Specific depressive symptoms are related with different patterns of alcohol use in community-dwelling older adults 

      Castellanos-Perilla, Nicolás; Borda, Miguel Germán; Cataño, Sara; Giraldo, Salomon; Vik-Mo, Audun Osland; Aarsland, Dag; Rao, Rahul Tony (Peer reviewed; Journal article, 2022)
      Objectives To explore how individual depressive symptoms might contribute to different patterns of alcohol consumption in Colombian older adults living in the community. Methods A Secondary analysis from a nationally ...
    • Specific neuropsychiatric symptoms are associated with functional decline trajectories in Alzheimer’s disease and Lewy body dementia: a five-year follow-up study 

      Borda, Miguel Germán; Brønnick, Kolbjørn Kallesten; Garcia-Cifuentes, Elkin; Jaramillo-Jiménez, Alberto; Reyes-Ortiz, Carlos; Patricio-Baldera, Jonathan; Sønnesyn, Hogne; Pérez-Zepeda, Mario Ulises; Vik-Mo, Audun Osland; Aarsland, Dag (Peer reviewed; Journal article, 2023)
      Background Neuropsychiatric symptoms (NPS) are often overlooked and under-identified symptoms associated with dementia, despite their significant impact on the prognosis of individuals living with the disease. The specific ...
    • Spectral features of resting-state EEG in Parkinson's Disease: A multicenter study using functional data analysis 

      Jaramillo-Jimenez, Alberto; Tovar-Rios, Diego Alejandro; Ospina, Johann Alexis; Mantilla-Ramos, Yorguin-Jose; Loaiza-López, Daniel; Henao Isaza, Verónica; Zapata Saldarriaga, Luisa María; Cadavid Castro, Valeria; Suarez-Revelo, Jazmin Ximena; Bocanegra, Yamile; Lopera, Francisco; Pineda-Salazar, David Antonio; Tobón Quintero, Carlos Andrés; Ochoa-Gomez, John Fredy; Borda, Miguel Germán; Aarsland, Dag; Bonanni, Laura; Brønnick, Kolbjørn Kallesten (Peer reviewed; Journal article, 2023)
      Objective This study aims 1) To analyse differences in resting-state electroencephalogram (rs-EEG) spectral features of Parkinson's Disease (PD) and healthy subjects (non-PD) using Functional Data Analysis (FDA) and 2) ...
    • The value of cerebrospinal fluid alpha-synuclein and the tau/alpha-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology 

      Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2019-07)
      Background and purpose Parkinson's disease (PD), dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are three of the most common neurodegenerative disorders. Up to 20% of these patients have the wrong diagnosis, ...
    • Timed Up and Go in People with Subjective Cognitive Decline Is Associated with Faster Cognitive Deterioration and Cortical Thickness 

      Borda, Miguel Germán; Ferreira, Daniel; Selnes, Per; Tovar-Rios, Diego Alejandro; Jaramillo-Jiménez, Alberto; Kirsebom, Bjørn-Eivind; Garcia-Cifuentes, Elkin; Dalaker, Turi Olene; Oppedal, Ketil; Sønnesyn, Hogne; Fladby, Tormod; Aarsland, Dag (Peer reviewed; Journal article, 2022)
      Introduction: Early markers of neurodegeneration provide an opportunity to detect, monitor, and initiate interventions in individuals who have an increased risk of developing dementia. Here, we investigated whether the ...
    • Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies 

      Borda, Miguel Germán; Castellanos-Perilla, Nicolás; Tovar-Rios, Diego Alejandro; Ferreira, Daniel; Duque, Gustavo; Aarsland, Dag (Peer reviewed; Journal article, 2022-02)
      Background Age-related neurodegeneration, sarcopenia, and ectopic fat accumulation are conditions with shared pathways that remain poorly understood. We have measured muscle volume and fat accumulation in masseter and ...
    • Using magnetic resonance imaging to measure head muscles: An innovative method to opportunistically determine muscle mass and detect sarcopenia 

      Borda, Miguel Germán; Duque, Gustavo; Pérez-Zepeda, Mario Ulises; Baldera, Jonathan Patricio; Westman, Eric; Zettergren, Anna; Samuelsson, Jessica; Kern, Silke; Rydén, Lina; Skoog, Ingmar; Aarsland, Dag (Peer reviewed; Journal article, 2023)
      Background Sarcopenia is associated with multiple adverse outcomes. Traditional methods to determine low muscle mass for the diagnosis of sarcopenia are mainly based on dual-energy X-ray absorptiometry (DXA), whole-body ...
    • White Matter Lesions and Pattern Recognition in MRI of Neurodegenerative Dementia 

      Oppedal, Ketil (PhD thesis UiS;, Doctoral thesis, 2016-11-03)
      Introduction Expected age is increasing globally and dementia is a common outcome for an increasing number of people. Dementia is a demanding syndrome for the patient and the environment as well as it is costly for ...