• Structural identifiability of biomolecular controller motifs with and without flow measurements as model output 

      Haus, Eivind Sandve; Drengstig, Tormod; Thorsen, Kristian (Peer reviewed; Journal article, 2023-08)
      Controller motifs are simple biomolecular reaction networks with negative feedback. They can explain how regulatory function is achieved and are often used as building blocks in mathematical models of biological systems. ...
    • Structural Properties of Biological Integral Feedback Motifs 

      Tveit, Daniel Myklatun (PhD thesis UiS;, Doctoral thesis, 2020-09)
      Cells are exposed to a range of external and internal disturbances that may influence the function of cellular processes. The ability of cells to self-regulate and adapt to disturbances enable them to maintain essential ...
    • A systems biology approach to cellular homeostasis, volume changes and regulation of metabolism 

      Fjeld, Gunhild (PhD thesis UiS;509, Doctoral thesis, 2020-04)
      Cells need to respond to a vast range of different disturbances and changes over small and large time scales. This can be disturbances in the form of molecules used to fight infectious states, changes in growth patterns, ...
    • The organization of controller motifs leading to robust plant iron homeostasis 

      Agafonov, Oleg; Selstø, Christina Helen; Thorsen, Kristian; Xiang, Ming Xu; Drengstig, Tormod; Ruoff, Peter (Journal article; Peer reviewed, 2016-01)
      Iron is an essential element needed by all organisms for growth and development. Because iron becomes toxic at higher concentrations iron is under homeostatic control. Plants face also the problem that iron in the soil is ...
    • Variable setpoint as a relaxing component in physiological control 

      Risvoll, Geir; Thorsen, Kristian; Ruoff, Peter; Drengstig, Tormod (Journal article; Peer reviewed, 2017-09)
      Setpoints in physiology have been a puzzle for decades, and especially the notion of fixed or variable setpoints have received much attention. In this paper, we show how previously presented homeostatic controller motifs, ...