Blar i UiS Brage på forfatter "Grimstad, Tore"
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Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease
Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Journal article; Peer reviewed, 2019-08)Background and Aim: Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut-off concentration of adalimumab ... -
Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease
Grimstad, Tore; Kvivik, Ingeborg; Kvaløy, Jan Terje; Aabakken, Lars; Omdal, Roald (Journal article; Peer reviewed, 2019-10)Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ...