Blar i UiS Brage på forfatter "Hagland, Hanne R."
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Effects of metformin and dichloroacetate on pancreatic cancer cells from the PANC-1 cell line
Aarvik, Anne Maren S. (Bachelor thesis, 2022)The metabolic drugs metformin and dichloroacetate was researched for their anticancer effects on pancreatic cancer cells from the PANC-1 cell line. Pancreatic cancer cells were treated with metformin and dichloroacetate ... -
Metabolic Cancer Therapy Using Graphene Drug Carriers: A study of biguanide drug effects in cellular and zebrafish larvae model systems
Alhourani, Abdelnour H. (PhD thesis UiS;, Doctoral thesis, 2021-11)Targeting cancer metabolism is an increasingly important strategy in the fight against cancer relapse. Metabolic drugs belonging to the biguanides family have gained attention in cancer treatment due to their ability to ... -
Metformin treatment response is dependent on glucose growth conditions and metabolic phenotype in colorectal cancer cells
Alhourani, Abdelnour H.; Tidwell, Tia R.; Bokil, Ansooya Avinash; Røsland, Gro V.; Tronstad, Karl Johan; Søreide, Kjetil; Hagland, Hanne R. (Peer reviewed; Journal article, 2021-05)Cancer cells exhibit altered metabolism, a phenomenon described a century ago by Otto Warburg. However, metabolic drug targeting is considered an underutilized and poorly understood area of cancer therapy. Metformin, a ... -
Modeling 3D cancer growth and extracellular matrix properties in vitro
Ahmad, Hina (Master thesis, 2018-08-15)Background: Cancer can be defined as loss of normal behavior of cellular components thus losing tissue organization and giving rise to a tumor microenvironment (TME). Increased matrix stiffness, strain and elevated ... -
The Effects of Metformin on the Metabolism of Colorectal Cancer Cell Lines SW948 and SW1116
Danby, Samuel James (Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-06)Metformin is an anti-diabetes drug with cancer preventative capabilities, which is widely studied to help develop treatment to aid future colorectal cancer prevention and recovery. This studies aims were to assess the ... -
Varme- og saltinduserte kvalitetsendringer i Atlantisk torsk (Gadus morhua)
Vaka, Mette Risa (Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-06-15)Baking av torsk i kokeskap er vanlig praksis både i matindustrien og på storkjøkken. Kokken velger passende program på grunnlag av erfaring, mens i matindustrien er holdbarhet ofte en viktig tilleggsfaktor. I sistnevnte ...