• Distinct Gene Expression Profiles of Matched Primary and Metastatic Triple-Negative Breast Cancers 

      Kaur, Jaspreet; Chandrashekar, Darshan S.; Varga, Zsuzsanna; Sobottka, Bettina; Janssen, Emiel; Kowalski, Jeanne; Kiraz, Umay; Varambally, Sooryanarayana; Aneja, Ritu (Peer reviewed; Journal article, 2022)
      Background: Although triple-negative breast cancer (TNBC) is associated with an increased risk of recurrence and metastasis, the molecular mechanisms underlying metastasis in TNBC remain unknown. To identify transcriptional ...
    • Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma 

      Roalsø, Marcus Thomas Thor; Hald, Øyvind; Alexeeva, Marina; Søreide, Kjetil (Peer reviewed; Journal article, 2022-01)
      Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment options. Emerging evidence shows that epigenetic alterations are present in PDAC. The changes are potentially reversible and therefore ...
    • Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System 

      Nordgård, Oddmund; Forthun, Rakel Brendsdal; Lapin, Morten; Grønberg, Bjørn Henning; Kalland, Karl Henning; Kopperud, Reidun Kristin; Thomsen, Liv Cecilie Vestrheim; Tjensvoll, Kjersti; Gilje, Bjørnar; Gjertsen, Bjørn Tore; Hovland, Randi (Peer reviewed; Journal article, 2021-04)
      Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ...
    • Platelet microparticles protect acute myelogenous leukemia cells against daunorubicin-induced apoptosis 

      Cacic, Daniel; Reikvam, Håkon; Nordgård, Oddmund; Meyer, Peter; Hervig, Tor (Peer reviewed; Journal article, 2021-04)
      The role of platelets in cancer development and progression is increasingly evident, and several platelet–cancer interactions have been discovered, including the uptake of platelet microparticles (PMPs) by cancer cells. ...