Browsing UiS Brage by Author "Baak, Jan P.A."
Now showing items 1-8 of 8
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Influence of pre-operative oral carbohydrate loading vs. standard fasting on tumor proliferation and clinical outcome in breast cancer patients - a randomized trial
Lende, Tone Hoel; Austdal, Marie; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Kvaløy, Jan Terje; Akslen, Lars A.; Søiland, Håvard; Janssen, Emiel; Baak, Jan P.A. (Journal article; Peer reviewed, 2019-11)Background Conflicting results have been reported on the influence of carbohydrates in breast cancer. Objective To determine the influence of pre-operative per-oral carbohydrate load on proliferation in breast ... -
Major bioactive chemical compounds in Astragali Radix samples from different vendors vary greatly
Kafle, Bijay; Baak, Jan P.A.; Brede, Cato (Peer reviewed; Journal article, 2021-07)The worldwide traditional Chinese medicine (TCM) herbs sales figures have increased considerably to 50 billion US$ (2018). Astragali Radix (AR) is amongst the most often sold TCM herbs; sales in the European Union (EU) ... -
Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study
Lende, Tone Hoel; Austdal, Marie; Bathen, Tone Frost; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Egeland, Nina Gran; Lunde, Siri; Akslen, Lars A.; Jonsdottir, Kristin; Janssen, Emiel; Søiland, Håvard; Baak, Jan P.A. (Journal article; Peer reviewed, 2019-12)Background The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ... -
MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers
Egeland, Nina Gran; Jonsdottir, Kristin; Aure, Miriam Ragle; Sahlberg, Kristine Kleivi; Kristensen, Vessela N.; Cronin-Fenton, Deirdre; Skaland, Ivar; Gudlaugsson, Einar; Baak, Jan P.A.; Janssen, Emiel (Peer reviewed; Journal article, 2020-05)Background Previously, we have shown that miR-18a and miR-18b gene expression strongly correlates with high proliferation, oestrogen receptor -negativity (ER−), cytokeratin 5/6 positivity and basal-like features of breast ... -
Prognostic value and reproducibility of different microscopic characteristics in the WHO grading systems for pTa and pT1 urinary bladder urothelial carcinomas
Kvikstad, Vebjørn; Mangrud, Målfrid Ok; Gudlaugsson, Einar; Dalen, Ingvild; Espeland, Hans; Baak, Jan P.A.; Janssen, Emiel (Peer reviewed; Journal article, 2019-08)Background: European treatment guidelines for pTa and pT1 urinary bladder urothelial carcinoma depend highly on stage and WHO-grade. Both the WHO73 and the WHO04 grading systems show some intra- and interobserver variability. ... -
Proliferation and immunohistochemistry for p53, CD25 and CK20 in predicting prognosis of non-muscle invasive papillary urothelial carcinomas
Kvikstad, Vebjørn; Lillesand, Melinda; Gudlaugsson, Einar; Mangrud, Ok Målfrid; Rewcastle, Emma; Skaland, Ivar; Baak, Jan P.A.; Janssen, Emiel (Peer reviewed; Journal article, 2024)Non-muscle invasive papillary urothelial carcinoma is a prevalent disease with a high recurrence tendency. Good prognostic and reproducible biomarkers for tumor recurrence and disease progression are lacking. Currently, ... -
Quantification by LC–MS/MS of astragaloside IV and isoflavones in Astragali radix can be more accurate by using standard addition
Kafle, Bijay; Baak, Jan P.A.; Brede, Cato (Peer reviewed; Journal article, 2020)Introduction Astragali radix (AR), the root of Astragalus, is an important medical herb widely used in traditional Chinese medicine. Bioactive components include isoflavones and a unique class of triterpenoid saponins ... -
Validation study of MARCKSL1 as a prognostic factor in lymph node-negative breast cancer patients
Egeland, Nina Gran; Austdal, Marie; Van Diermen, Bianca; Rewcastle, Emma; Gudlaugsson, Einar; Baak, Jan P.A.; Skaland, Ivar; Janssen, Emiel; Jonsdottir, Kristin (Peer reviewed; Journal article, 2019)Protein expression of Myristoylated alanine-rich C kinase substrate like-1 (MARCKSL1) has been identified as a prognostic factor in lymph-node negative (LN-) breast cancer patients. We aim to validate MARCKSL1 protein ...