• Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients 

      Egeland, Nina Gran; Jonsdottir, Kristin; Lauridsen, Kristina Lystlund; Skaland, Ivar; Hjorth, Cathrine F.; Gudlaugsson, Einar; Hamilton-Dutoit, Stephen Jacques; Lash, Timothy L.; Cronin-Fenton, Deidre; Janssen, Emiel (Peer reviewed; Journal article, 2020-07)
      Purpose: The proliferation marker Ki-67 has been used as a prognostic marker to separate low- and high-risk breast cancer subtypes and guide treatment decisions for adjuvant chemotherapy. The association of Ki-67 with ...
    • Discovery and Validation of Biomarkers in Breast Cancer 

      Egeland, Nina Gran (PhD thesis UiS;546, Doctoral thesis, 2020-09)
      Worldwide, breast cancer is the most common malignancy among women, and although treatment and prognosis have improved substantially over the last decades, for some patients the risk of recurrence remains for several years ...
    • Fatigue in primary Sjögren's syndrome: A proteomic pilot study of cerebrospinal fluid 

      Larssen, Eivind; Brede, Cato; Hjelle, Anne; Tjensvoll, Anne Bolette; Norheim, Katrine Brække; Bårdsen, Kjetil; Jonsdottir, Kristin; Ruoff, Peter; Omdal, Roald; Nilsen, Mari Mæland (Peer reviewed; Journal article, 2019-05)
      Objectives: Fatigue is a frequent and often disabling phenomenon that occurs in patients with chronic inflammatory and immunological diseases, and the underlying biological mechanisms are largely unknown. Because fatigue ...
    • Heat Shock Proteinα and Fatigue in Breast Cancer - A Cross Sectional Study 

      Andersen, Torill (Master thesis, 2021)
      Breast cancer is the most frequent malignancy among women and is often associated with fatigue during treatment. Fatigue may be considered as a sickness behavior syndrome, which is induced by activation of the innate immune ...
    • Metabolic consequences of perioperative oral carbohydrates in breast cancer patients - an explorative study 

      Lende, Tone Hoel; Austdal, Marie; Bathen, Tone Frost; Varhaugvik, Anne Elin; Skaland, Ivar; Gudlaugsson, Einar; Egeland, Nina Gran; Lunde, Siri; Akslen, Lars A.; Jonsdottir, Kristin; Janssen, Emiel; Søiland, Håvard; Baak, Jan P.A. (Journal article; Peer reviewed, 2019-12)
      Background The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative ...
    • MiR-18a and miR-18b are expressed in the stroma of oestrogen receptor alpha negative breast cancers 

      Egeland, Nina Gran; Jonsdottir, Kristin; Aure, Miriam Ragle; Sahlberg, Kristine Kleivi; Kristensen, Vessela N.; Cronin-Fenton, Deirdre; Skaland, Ivar; Gudlaugsson, Einar; Baak, Jan P.A.; Janssen, Emiel (Peer reviewed; Journal article, 2020-05)
      Background Previously, we have shown that miR-18a and miR-18b gene expression strongly correlates with high proliferation, oestrogen receptor -negativity (ER−), cytokeratin 5/6 positivity and basal-like features of breast ...
    • miRNA normalization enables joint analysis of several datasets to increase sensitivity and to reveal novel miRNAs differentially expressed in breast cancer 

      Ben-Elazar, Shay; Aure, Miriam Ragle; Jonsdottir, Kristin; Leivonen, Suvi-Katri; Kristensen, Vessela N.; Janssen, Emiel; Sahlberg, Kristine Kleivi; Lingjærde, Ole Christian; Yakhini, Zohar (Peer reviewed; Journal article, 2021-02)
      Different miRNA profiling protocols and technologies introduce differences in the resulting quantitative expression profiles. These include differences in the presence (and measurability) of certain miRNAs. We present and ...
    • The role of microRNAs as predictors of response to tamoxifen treatment in breast cancer patients 

      Egeland, Nina; Lunde, Siri; Jonsdottir, Kristin; Lende, Tone Hoel; Cronin-Fenton, Deirdre P.; Gilje, Bjørnar; Janssen, Emilius Adrianus Maria; Søiland, Håvard (Journal article; Peer reviewed, 2015-10)
      Endocrine therapy is a key treatment strategy to control or eradicate hormone-responsive breast cancer. However, resistance to endocrine therapy leads to breast cancer relapse. The recent extension of adjuvant tamoxifen ...