Browsing UiS Brage by Author "Lillesand, Melinda"
Now showing items 1-6 of 6
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Automatic diagnostic tool for predicting cancer grade in bladder cancer patients using deep learning
Wetteland, Rune; Engan, Kjersti; Eftestøl, Trygve Christian; Kvikstad, Vebjørn; Janssen, Emiel; Tøssebro, Erlend; Lillesand, Melinda (Peer reviewed; Journal article, 2021-08)The most common type of bladder cancer is urothelial carcinoma, which is among the cancer types with the highest recurrence rate and lifetime treatment cost per patient. Diagnosed patients are stratified into risk groups, ... -
High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling
Øvestad, Irene Tveiterås; Engesæter, Birgit Øvstebø; Halle, Mari Kyllesø; Akbari, Saleha; Bicskei, Beatrix; Lapin, Morten; Austdal, Marie; Janssen, Emiel; Krakstad, Camilla; Lillesand, Melinda; Nordhus, Marit; Munk, Ane Cecilie Dæhli; Gudlaugsson, Einar (Peer reviewed; Journal article, 2021-12)Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. ... -
Integrating Genetic Alterations and Histopathological Features for Enhanced Risk Stratification in Non-Muscle-Invasive Bladder Cancer
Lillesand, Melinda; Kvikstad, Vebjørn; Gudlaugsson, Einar; Skaland, Ivar; Slewa Johannessen, Aida; Tesfahun, Almaz Nigatu; Sperstad, Sigmund; Janssen, Emiel; Austdal, Marie (Peer reviewed; Journal article, 2024)Background: Urothelial carcinoma presents as non-muscle-invasive bladder cancer (NMIBC) in ~75% of primary cases. Addressing the limitations of the TNM and WHO04/16 classification systems, this study investigates genetic ... -
Mitotic activity index and CD25+ lymphocytes predict risk of stage progression in non-muscle invasive bladder cancer
Lillesand, Melinda; Kvikstad, Vebjørn; Mangrud, Målfrid Ok; Gudlaugsson, Einar; Van Diermen, Bianca; Skaland, Ivar; Baak, Johannes Peter A; Janssen, Emiel (Peer reviewed; Journal article, 2020-06)In urothelial cell type non-muscle invasive urinary bladder carcinoma, TNM stage and WHO grade are widely used to classify patients into low and high-risk groups for prognostic and therapeutic decision-making. However, ... -
Proliferation and immunohistochemistry for p53, CD25 and CK20 in predicting prognosis of non-muscle invasive papillary urothelial carcinomas
Kvikstad, Vebjørn; Lillesand, Melinda; Gudlaugsson, Einar; Mangrud, Ok Målfrid; Rewcastle, Emma; Skaland, Ivar; Baak, Jan P.A.; Janssen, Emiel (Peer reviewed; Journal article, 2024)Non-muscle invasive papillary urothelial carcinoma is a prevalent disease with a high recurrence tendency. Good prognostic and reproducible biomarkers for tumor recurrence and disease progression are lacking. Currently, ... -
A template to quantify the location and density of CD3 + and CD8 + tumor-infiltrating lymphocytes in colon cancer by digital pathology on whole slides for an objective, standardized immune score assessment
Lea, Dordi; Watson, Martin Matthew Christian; Skaland, Ivar; Hagland, Hanne Røland; Lillesand, Melinda; Gudlaugsson, Einar; Søreide, Kjetil (Peer reviewed; Journal article, 2021)Background In colon cancer, the location and density of tumor-infiltrating lymphocytes (TILs) can classify patients into low and high-risk groups for prognostication. While a commercially available ‘Immunoscore®’ exists, ...