Browsing UiS Brage by Author "Ørn, Stein"
Now showing items 1-20 of 21
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6 min walk test is a strong independent predictor of death in outpatients with heart failure
Grundtvig, Morten; Eriksen-Volnes, Torfinn; Ørn, Stein; Slind, Eva Kjøl; Gullestad, Lars (Peer reviewed; Journal article, 2020)Aims The aim of this study was to examine the prognostic value of the 6 min walk test (6MWT) in a large cohort of outpatients with heart failure. Methods and results A total of 5519 outpatients with heart failure from ... -
Artifact Correction in Short-Term HRV during Strenuous Physical Exercise
Krolak, Aleksandra; Wiktorski, Tomasz; Bjørkavoll-Bergseth, Magnus; Ørn, Stein (Peer reviewed; Journal article, 2020-11)Heart rate variability (HRV) analysis can be a useful tool to detect underlying heart or even general health problems. Currently, such analysis is usually performed in controlled or semi-controlled conditions. Since many ... -
Cardiac Structure and Function in Epilepsy Patients with Drug-Resistant Convulsive Seizures
Gonzalez, Alba; Haugaa, Kristina Ingrid Helena Hermann; Brekke, Pål Haugar; Hopp, Einar; Ørn, Stein; Alvestad, Silje; Taubøll, Erik; Aurlien, Dag (Peer reviewed; Journal article, 2022)High frequency of convulsive seizures and long-lasting epilepsy are associated with an increased risk of sudden unexpected death in epilepsy (SUDEP). Structural changes in the myocardium have been described in SUDEP victims. ... -
Changes in 6-min walk test is an independent predictor of death in chronic heart failure with reduced ejection fraction
Myhre, Peder Langeland; Kleiven, Øyunn; Berge, Kristian; Grundtvig, Morten; Gullestad, Lars; Ørn, Stein (Peer reviewed; Journal article, 2024)Aims Functional capacity provides important clinical information in patients with heart failure (HF) and reduced ejection fraction (HFrEF). The 6-min walk test (6MWT) is a simple and inexpensive tool for assessing functional ... -
Determinants of interindividual variation in exercise-induced cardiac troponin i levels
Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Eijsvogels, Thijs M. H.; Skadberg, Øyvind; Frøysa, Vidar; Wiktorski, Tomasz; Auestad, Bjørn; Edvardsen, Thor; Aakre, Kristin Moberg; Ørn, Stein (Peer reviewed; Journal article, 2021-08)Background Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 ... -
Duration of elevated heart rate Is an important predictor of exercise-induced troponin elevation
Bjørkavoll-Bergseth, Magnus; Kleiven, Øyunn; Auestad, Bjørn Henrik; Eftestøl, Trygve Christian; Oskal, Kay Raymond; Nygård, Martin; Skadberg, Øyvind; Aakre, Kristin Moberg; Melberg, Tor Harald; Gjesdal, Knut; Ørn, Stein (Peer reviewed; Journal article, 2020)Background The precise mechanisms causing cardiac troponin (cTn) increase after exercise remain to be determined. The aim of this study was to investigate the impact of heart rate (HR) on exercise‐induced cTn increase by ... -
Echocardiographic assessment of myocardial efficiency predicts exercise performance
Erevik, Christine Bjørkvik; Kleiven, Øyunn; Frøysa, Vidar; Bjørkavoll-Bergseth, Magnus; Chivulescu, Ana Monica; Klæboe, Lars Gunnar; Dejgaard, Lars; Auestad, Bjørn Henrik; Skadberg, Øyvind; Melberg, Tor Harald; Urheim, Stig; Haugaa, Kristina Ingrid Helena Hermann; Edvardsen, Thor; Ørn, Stein (Peer reviewed; Journal article, 2024)Cardiac function is a major determinant of cardiopulmonary fitness. This study aimed to determine if novel echocardiographic myocardial function and efficiency parameters at rest can predict exercise performance during ... -
Endurance exercise training volume is not associated with progression of coronary artery calcification
Kleiven, Øyunn; Bjørkavoll-Bergseth, Magnus; Omland, Torbjørn; Aakre, Kristin Moberg; Frøysa, Vidar; Erevik, Christine B.; Greve, Ole Jacob; Melberg, Tor Harald; Auestad, Bjørn Henrik; Skadberg, Øyvind; Edvardsen, Thor; Ørn, Stein (Peer reviewed; Journal article, 2020-02)Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ... -
Exercise-Induced Cardiac Troponin Elevations: From Underlying Mechanisms to Clinical Relevance
Aengevaeren, Vincent L; Baggish, Aaron L; Chung, Eugene H.; George, Keith; Kleiven, Øyunn; Mingels, Alma M. A.; Ørn, Stein; Shave, Rob E.; Thompson, Paul; Eijsvogels, Thijs M. H. (Peer reviewed; Journal article, 2021)Serological assessment of cardiac troponins (cTn) is the gold standard to assess myocardial injury in clinical practice. A greater magnitude of acutely or chronically elevated cTn concentrations is associated with lower ... -
High dose statin treatment reduces circulating Dickkopf-1 following acute myocardial infarction
Ueland, Thor; Butt, Noreen; Lekva, Tove; Ørn, Stein; Manhenke, Cord Arend; Aukrust, Pål; Larsen, Alf Inge (Peer reviewed; Journal article, 2024-07)Background Secreted glycoproteins of the Dickkopf (DKK) family modify Wnt signaling and may influence plaque destabilization but their modulation by statins in MI patients is not known. Methods We measured plasma DKK-1 ... -
High-Sensitivity Cardiac Troponin I and T Response Following Strenuous Activity is Attenuated by Smokeless Tobacco: NEEDED (North Sea Race Endurance Exercise Study) 2014
Skranes, Julia Brox; Kleiven, Øyunn; Aakre, Kristin Moberg; Skadberg, Øyvind; Melberg, Tor Harald; Omland, Torbjørn; Ørn, Stein (Peer reviewed; Journal article, 2020)Background Use of snus, a smokeless tobacco product, is increasing in Scandinavia. Strenuous physical activity is associated with an acute increase in high‐sensitivity cardiac troponin (swhs‐cTn) concentrations. Current ... -
Methods for preprocessing time and distance series data from personal monitoring devices
Wiktorski, Tomasz; Bjørkavoll-Bergseth, Magnus; Ørn, Stein (Peer reviewed; Journal article, 2020-06)There is a need to develop more advanced tools to improve guidance on physical exercise to reduce risk of adverse events and improve benefits of exercise. Vast amounts of data are generated continuously by Personal Monitoring ... -
Occult obstructive coronary artery disease is associated with prolonged cardiac troponin elevation following strenuous exercise
Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-06)Background Sudden cardiac death among middle-aged recreational athletes is predominantly due to myocardial ischaemia. This study examined whether measuring cardiac troponin I and T (cTnI and cTnT) after strenuous exercise ... -
Probability mapping of scarred myocardium using texture and intensity features in CMR images
Kotu, Lasya Priya; Engan, Kjersti; Skretting, Karl; Måløy, Frode; Ørn, Stein; Woie, Leik; Eftestøl, Trygve (Journal article, 2013) -
Race duration and blood pressure are major predictors of exercise-induced cardiac troponin elevation
Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-02)Background The underlying mechanisms of the exercise-induced increase in cardiac troponins (cTn) are poorly understood. The aim of this study was to identify independent determinants of exercise-induced cTn increase in a ... -
Recurrent Neural Networks for Artifact Correction in HRV Data During Physical Exercise
Svane, Jakob; Wiktorski, Tomasz; Ørn, Stein; Eftestøl, Trygve Christian (Peer reviewed; Journal article, 2023)In this paper, we propose the use of recurrent neural networks (RNNs) for artifact correction and analysis of heart rate variability (HRV) data. HRV can be a valuable metric for determining the function of the heart and ... -
Regular consumption of cod liver oil is associated with reduced basal and exercise-induced C-reactive protein levels; a prospective observational trial
Hansen, Mette Wærstad; Ørn, Stein; Erevik, Christine Bjørkvik; Bjørkavoll-Bergseth, Magnus; Skadberg, Øyvind; Melberg, Tor Harald; Aakre, Kristin Moberg; Kleiven, Øyunn (Peer reviewed; Journal article, 2021-06)Background Dietary supplement use among recreational athletes is common, with the intention of reducing inflammation and improving recovery. We aimed to describe the relationship between omega-3 fatty acid supplement use ... -
The relationship between Fibroblast Growth Factor 23 (FGF23) and cardiac MRI findings following primary PCI in patients with acute first time STEMI
Thorsen, Inga Strand; Gøransson, Lasse Gunnar; Ueland, Thor; Aukrust, Pål; Manhenke, Cord A; Skadberg, Øyvind; Jonsson, Grete; Ørn, Stein (Peer reviewed; Journal article, 2021-04)Background Fibroblast growth factor 23 (FGF23) is a regulator of mineral metabolism, that has been linked to myocardial remodeling including development of left ventricular (LV) hypertrophy and myocardial fibrosis. The ... -
The relationship between workload and exercise-induced cardiac troponin elevations is influenced by non-obstructive coronary atherosclerosis
Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Wiktorski, Tomasz; Auestad, Bjørn Henrik; Skadberg, Øyvind; Aakre, Kristin Moberg; Eijsvogels, Thijs M. H.; Ørn, Stein (Peer reviewed; Journal article, 2024-05)The relationship between exercise-induced troponin elevation and non-obstructive coronary artery disease (CAD) is unclear. This observational study assessed non-obstructive CAD's impact on exercise-induced cardiac Troponin ... -
Texture-based probability mapping for automatic scar assessment in late gadolinium-enhanced cardiovascular magnetic resonance images
Frøysa, Vidar; Berg, Gøran Jansson; Eftestøl, Trygve Christian; Woie, Leik; Ørn, Stein (Peer reviewed; Journal article, 2021-12)Purpose To evaluate a novel texture-based probability mapping (TPM) method for scar size estimation in LGE-CMRI. Methods This retrospective proof-of-concept study included chronic myocardial scars from 52 patients. ...