Blar i Faculty of Science and Technology på emneord "nevrologi"

Viser treff 1-7 av 7

    • Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease. 

      Grødem, Jodi Maple; Dalen, Ingvild; Tysnes, Ole-Bjørn; Macleod, Angus D.; Forsgren, Lars; Counsell, Carl E.; Alves, Guido Werner (Peer reviewed; Journal article, 2020-12)
      Objective To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). Methods Three European population-based ...

    • Combinatory microRNA serum signatures as classifiers of Parkinson's disease 

      Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Journal article; Peer reviewed, 2019-04)
      As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ...

    • The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies 

      Abdelnour, Carla; Ferreira, Daniel; Oppedal, Ketil; Cavallin, Lena; Bousiges, Olivier; Wahlund, Lars Olof; Hort, Jakub; Nedelska, Zuzana; Padovani, Alessandro; Pilotto, Andrea; Bonanni, Laura; Kramberger, Milica Gregoric; Boada, Mercè; Westman, Eric; Pagonabarraga, Javier; Kulisevsky, Jaime; Blanc, Frédéric; Aarsland, Dag (Peer reviewed; Journal article, 2020-07)
      Background Alzheimer’s disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in ...

    • Early constipation predicts faster dementia onset in Parkinson's disease 

      Camacho, Marta; Macleod, Angus D.; Grødem, Jodi Maple; Evans, Jonathan R.; Breen, David P.; Cummins, G; Wijeyekoon, Ruwani; Greenland, Julia; Alves, Guido Werner; Tysnes, Ole-Bjørn; Lawson, Rachel A.; Barker, Roger A.; Williams-Gray, Caroline H. (Peer reviewed; Journal article, 2021-05)
      Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ...

    • Excessive Daytime Sleepiness and REM Sleep Behavior Disorders in Parkinson's Disease: A Narrative Review on Early Intervention With Implications to Neuroprotection 

      Gjerstad, Michaela D; Alves, Guido Werner; Maple-Grødem, Jodi (Journal article; Peer reviewed, 2018-11)
      Sleep contributes to the consolidation of our memory and facilitates learning. Short term sleep deprivation temporarily reduces mnestic capacity, whereas long lasting sleep deprivation is associated with structural changes ...

    • First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes 

      Green, Samantha; Perrott, Sarah L.; McCleary, Andrew; Sleeman, Isobel; Maple-Grødem, Jodi; Counsell, Carl E.; Macleod, Angus D. (Peer reviewed; Journal article, 2021-10)
      To define the incidence, predictors and prognosis of the first hospital delirium episode in Parkinson’s disease (PD) and atypical parkinsonism (AP), we identified the first hospital episode of delirium after diagnosis in ...

    • Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci 

      Gaare, Johannes Jernqvist; Sanchez Nido, Gonzalo; Dölle, Christian; Sztromwasser, Pawel Szymon; Alves, Guido Werner; Tysnes, Ole-Bjørn; Haugarvoll, Kristoffer; Tzoulis, Charalampos (Peer reviewed; Journal article, 2020-10)
      Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ...