• Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids 

      Hassan, Ashraf S.; Moustafa, Gaber O.; Awad, Hanem M.; Nossier, Eman S.; Mady, Mohamed Fawzy Hamed Attia (Peer reviewed; Journal article, 2021-04)
      The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ...
    • Kinase chemodiversity from the Arctic: the breitfussins 

      Østnes Hansen, Kine; Andersen, Jeanette hammer; Bayer, Annette; Pandey, Sunil Kumar; Lorentzen, Marianne; Jørgensen, Kåre Bredeli; Sydnes, Magne Olav; Guttormsen, Yngve; Baumann, Matthias; Koch, Uwe; Klebl, Bert; Eickhoff, Jan; Haug, Bengt Erik; Isaksson, Johan; Hansen, Espen (Journal article; Peer reviewed, 2019-10)
      In this work, we demonstrate that the indole-oxazole-pyrrole framework of the breitfussin family of natural products is a promising scaffold for kinase inhibition. Six new halogenated natural products, breitfussin C–H (3 ...
    • Natural peptides with antioxidant activity from Atlantic cod and Atlantic salmon residual material 

      Pampanin, Daniela M.; Haar, Marianne Bore; Sydnes, Magne Olav (Journal article; Peer reviewed, 2016-03)
      Summary. Water-soluble peptides/proteins with molecular weight below 10 kDa were isolated from residual material of cod (liver, skin, and cod mix i.e. skin, frames, and viscera), and salmon (skin, and salmon mix i.e. skin, ...