• Classifying dementia using local binary patterns from different regions in magnetic resonance images 

      Oppedal, Ketil; Eftestøl, Trygve; Engan, Kjersti; Beyer, Mona K.; Aarsland, Dag (Journal article; Peer reviewed, 2015)
      Dementia is an evolving challenge in society, and no disease-modifying treatment exists. Diagnosis can be demanding and MR imaging may aid as a noninvasive method to increase prediction accuracy. We explored the use of 2D ...
    • Combinatory microRNA serum signatures as classifiers of Parkinson's disease 

      Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Journal article; Peer reviewed, 2019-04)
      As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ...
    • The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies 

      Abdelnour, Carla; Ferreira, Daniel; Oppedal, Ketil; Cavallin, Lena; Bousiges, Olivier; Wahlund, Lars Olof; Hort, Jakub; Nedelska, Zuzana; Padovani, Alessandro; Pilotto, Andrea; Bonanni, Laura; Kramberger, Milica Gregoric; Boada, Mercè; Westman, Eric; Pagonabarraga, Javier; Kulisevsky, Jaime; Blanc, Frédéric; Aarsland, Dag (Peer reviewed; Journal article, 2020-07)
      Background Alzheimer’s disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in ...
    • Effects of purified anthocyanins in people at risk for dementia: Study protocol for a phase II randomized controlled trial 

      Khalifa, Khadija; Bergland, Anne Katrine; Sønnesyn, Hogne; Oppedal, Ketil; Oesterhus, Ragnhild; Dalen, Ingvild; Larsen, Alf Inge; Fladby, Tormod; Brooker, Helen; Wesnes, Keith A.; Ballard, Clive; Aarsland, Dag (Peer reviewed; Journal article, 2020)
      Background: The number of people with dementia is increasing, with huge challenges for society and health-care systems. There are no disease-modifying therapies available. There is, therefore, an urgent need to identify ...
    • MRI data-driven clustering reveals different subtypes of Dementia with Lewy bodies 

      Inguanzo, Anna; Poulakis, Konstantinos; Mohanty, Rosaleena; Schwarz, Christopher G.; Przybelski, Scott A.; Diaz-Galvan, Patricia; Lowe, Val J.; Boeve, Bradley F.; Lemstra, Afina W.; van de Beek, Marleen; van der Flier, Wiesje; Barkhof, Frederik; Blanc, Frederic; Loureiro de Sousa, Paulo; Philippi, Nathalie; Cretin, Benjamin; Demuynck, Catherine; Nedelska, Zuzana; Hort, Jakub; Segura, Barbara; Junque, Carme; Oppedal, Ketil; Aarsland, Dag; Westman, Eric; Kantarci, Kejal; Ferreira, Daniel (Peer reviewed; Journal article, 2023)
      Dementia with Lewy bodies (DLB) is a neurodegenerative disorder with a wide heterogeneity of symptoms, which suggests the existence of different subtypes. We used data-driven analysis of magnetic resonance imaging (MRI) ...
    • Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data 

      Abdelnour, Carla; Ferreira, Daniel; van de Beek, Marleen; Cedres, Nira; Oppedal, Ketil; Cavallin, Lena; Blanc, Frédéric; Bousiges, Olivier; Wahlund, Lars-Olof; Pilotto, Andrea; Padovani, Alessandro; Boada, Mercè; Pagonabarraga, Javier; Kulisevsky, Jaime; Aarsland, Dag; Lemstra, Afina W.; Westman, Eric (Peer reviewed; Journal article, 2022)
      Background Dementia with Lewy bodies (DLB) includes various core clinical features that result in different phenotypes. In addition, Alzheimer’s disease (AD) and cerebrovascular pathologies are common in DLB. All this ...
    • Self-reported sleep fragmentation and sleep duration and their association with cognitive function in PROTECT, a large digital community-based cohort of people over 50 

      Aakre, Jon Arild; Schulz, Jörn; Ballard, Clive; Corbett, Anne; Bjorvatn, Bjørn; Aarsland, Dag; Creese, Byron; Hampshire, Adam; Brooker, Helen; Testad, Ingelin (Peer reviewed; Journal article, 2023)
      Objective Sleep is vital for normal cognitive function in daily life, but is commonly disrupted in older adults. Poor sleep can be detrimental to mental and physical health, including cognitive function. This study assessed ...
    • White Matter Lesions and Pattern Recognition in MRI of Neurodegenerative Dementia 

      Oppedal, Ketil (PhD thesis UiS;, Doctoral thesis, 2016-11-03)
      Introduction Expected age is increasing globally and dementia is a common outcome for an increasing number of people. Dementia is a demanding syndrome for the patient and the environment as well as it is costly for ...