Blar i Faculty of Science and Technology på forfatter "Fenaroli, Federico"
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In vivo biodistribution of lipid nanoparticles in zebrafish embryo
Nielsen, Ida Tangen; Frøytlog, Madelen Aliganga (Bachelor thesis, 2023)Nanoparticles (NPs) are particles within the size range of 1-100 nm with distinctive surface structures that can act as transport particles of numerous substances. These properties allow for applications in a variety of ... -
In vivo biodistribution of lipid nanoparticles in zebrafish embryo
Nielsen, Ida Tangen; Frøytlog, Madelen Aliganga (Bachelor thesis, 2023)Nanoparticles (NPs) are particles within the size range of 1-100 nm with distinctive surface structures that can act as transport particles of numerous substances. These properties allow for applications in a variety of ... -
Modular Synthesis of Semiconducting Graft Copolymers to Achieve “Clickable” Fluorescent Nanoparticles with Long Circulation and Specific Cancer Targeting
Creamer, Adam; Fiego, Alessandra Lo; Agliano, Alice; Prados-Martin, Lino; Høgset, Håkon; Najer, Adrian; Richards, Daniel A.; Wojciechowski, Jonathan P.; Foote, James E. J.; Kim, Nayoung; Monahan, Amy; Tang, Jiaqing; Shamsabadi, André; Rochet, Léa N. C.; Thanasi, Ioanna A.; de la Ballina, Laura R; Rapley, Charlotte L.; Turnock, Stephen; Love, Elizabeth A.; Bugeon, Laurence; Dallman, Margaret J.; Heeney, Martin; Kramer-Marek, Gabriela; Chudasama, Vijay; Fenaroli, Federico; Stevens, Molly M. (Peer reviewed; Journal article, 2023)Semiconducting polymer nanoparticles (SPNs) are explored for applications in cancer theranostics because of their high absorption coefficients, photostability, and biocompatibility. However, SPNs are susceptible to aggregation ... -
mRNA Expression of EGFP by lipid nanoparticles
Motland, Bjørnar Naaden (Bachelor thesis, 2024)Two scientists, Katalin Karikó and Drew Weismann of Pennsylvania state university began research on mRNA as protein replacement therapeutics in the 90’s, but due to the mRNA’s immunogenicity it could not be used. However, ... -
Subcellular localization and therapeutic efficacy of polymeric micellar nanoparticles encapsulating bedaquiline for tuberculosis treatment in zebrafish
Bhandari, Madhavi; Soria-Carrera, Héctor; Wohlmann, Jens; Dal, Nils-Jørgen; de la Fuente, Jesús M.; Martín-Rapún, Rafael; Griffiths, Gareth Wyn; Fenaroli, Federico (Peer reviewed; Journal article, 2023)The combination drug regimens that have long been used to treat tuberculosis (TB), caused by Mycobacterium tuberculosis, are fraught with problems such as frequent administration, long duration of treatment, and harsh ... -
Π-Π interactions stabilize PeptoMicelle-based formulations of Pretomanid derivatives leading to promising therapy against tuberculosis in zebrafish and mouse models
Dal, Nils-Jørgen; Schäfer, Gabriela; Thompson, Andrew; Schmitt, Sascha; Redinger, Natalja; Alonso Rodriguez, Noelia; Johann, Kerstin; Ojong, Jessica; Wohlmann, Jens; Best, Andreas; Koynov, Kaloian; Zentel, Rudolf; Schaible, Ulrich E.; Griffiths, Gareth Wyn; Barz, Matthias; Fenaroli, Federico (Peer reviewed; Journal article, 2023)Tuberculosis is the deadliest bacterial disease globally, threatening the lives of millions every year. New antibiotic therapies that can shorten the duration of treatment, improve cure rates, and impede the development ...