Browsing Master's theses (TN-IMN, 2007-2017) by Subject "biological chemistry"
Now showing items 1-9 of 9
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Alpha-Synuclein and synuceinopathies as related to Parkinson's disease
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-06-15)Parkinson’s disease (PD) is a chronic, progressive, complex, age-related and movement neurodegenerative disorder, caused by the loss of dopaminergic neurons in a small portion of cells within the mid brain known as the ... -
Base excision repair of N4,5-dimethylcytosine in DNA
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-07-13)5-Methylcytosine (m5C) replaces cytosine (C) in DNA in prokaryotic and eukaryotic cells to execute a number of important cellular functions, but damage to m5C have received little attention. For instance, almost no studies ... -
Circulating and disseminated tumour cells as potential biomarkers for treatment response and disease progression in patients with locally advanced and/or metastatic pancreatic cancer
(Masteroppgave/UIS-TN-IMN/2013;, Master thesis, 2013-06-13)Introduction: Pancreatic cancer is the fourth most common cause of cancer related deaths in the Western countries. The poor prognosis of pancreatic cancer patients is often associated with early dissemination of the disease, ... -
Detection and Characterization of Circulating Tumor Cells in Early Breast Cancer
(Masteroppgave/UIS-TN-IMN/2016;, Master thesis, 2016-06)Background: Detection of circulating tumor cells (CTCs) has demonstrated prognostic significance in metastatic breast cancer. This is less studied in early breast cancer due to the rarity of such cells in early disease and ... -
Determination of protein composition in whey fractions by molecular spectroscopy, gel electrophoresis and mass spectrometry
(Masteroppgave/UIS-TN-IMN/2015;, Master thesis, 2015-06-15)Whey is becoming an important product for the dairy industry. In the last 15 years, the characterization of whey proteins (β-lactoglobulin (β-Lg), α-lactalbumin (α-La), Bovine serum albumin (BSA), Immunoglobulin (Ig), ... -
Employing CRISPR-Cas9 approach for DNA free editing of Solanum lycopersicum genome with pre-assembled CRISPR-Cas9 ribonucleoproteins and transcripts
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-06)In recent years there has been an increase in new demands in the agriculture sector due to factors as an increasing population, climate changes and food supplies. Hence, producing more food on less space has become a huge ... -
Metabolic Assessment of Metformin Treatment in Colon Cancer Cells
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-06-01)Resistance against traditional chemotherapy is a challenge in the treatment of colorectal cancer (CRC). The use of metformin, a commonly prescribed biguanide anti-diabetic drug, has shown to correlate with cancer preventive ... -
Metabolic assessment of metformin treatment in the colon cancer cell line SW1116.
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-06-02)Cancers have different metabolic profiles, with varying dependency on glycolysis and mitochondrial oxidative phosphorylation (OXPHOS). The metabolic profile of cancer influences it sensitivity to treatments. Metformin, an ... -
The development of a method for solubilisation of dark etioplast and the regulation of Chlorophyll binding to the Cytochrome b6f complex during deetiolation.
(Masteroppgave/UIS-TN-IMN/2017;, Master thesis, 2017-06)During photosynthesis light energy in used to make ATP, during this process cytochrome b6f acts as a link between photosystem I and II. Cytochrome b6f received electrons from photosystem II and passes them to photosystem ...