Blar i Publikasjoner fra CRIStin på emneord "VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Onkologi: 762"
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Anastomotic leak after surgery for colon cancer and effect on long‐term survival
(Peer reviewed; Journal article, 2020-02)Aim An anastomotic leak after surgery for colon cancer is a recognized complication but how it may adversely affect long‐term survival is less clear because data are scarce. The aim of the study was to investigate the ... -
Artificial intelligence in BreastScreen Norway: a retrospective analysis of a cancer-enriched sample including 1254 breast cancer cases
(Peer reviewed; Journal article, 2023-03)Objectives To compare results of selected performance measures in mammographic screening for an artificial intelligence (AI) system versus independent double reading by radiologists. Methods In this retrospective ... -
Automated Diagnosis of Prostate Cancer Using mpMRI Images: A Deep Learning Approach for Clinical Decision Support
(Peer reviewed; Journal article, 2023)Prostate cancer (PCa) is a significant health concern for men worldwide, where early detection and effective diagnosis can be crucial for successful treatment. Multiparametric magnetic resonance imaging (mpMRI) has evolved ... -
Automatic diagnostic tool for predicting cancer grade in bladder cancer patients using deep learning
(Peer reviewed; Journal article, 2021-08)The most common type of bladder cancer is urothelial carcinoma, which is among the cancer types with the highest recurrence rate and lifetime treatment cost per patient. Diagnosed patients are stratified into risk groups, ... -
Can cancer cells inform us about the tumor microenvironment?
(Peer reviewed; Journal article, 2023)Characteristics of the tumor microenvironment (TME) such as the leaky intratumoral vascular network and the density and composition of the desmoplastic extracellular matrix (ECM) contain essential information that determine ... -
Cancer-related fatigue and treatment burden in surgically treated colorectal cancer patients – A cross-sectional study
(Peer reviewed; Journal article, 2021)Objective This cross-sectional study aimed to describe cancer-related fatigue (CRF) in colorectal cancer (CRC) patients who were surgically treated with curative intent, identify subgroups at risk of elevated fatigue ... -
Days at home in the last three months of life: patterns-of-care analysis in patients with non-small cell lung cancer
(Peer reviewed; Journal article, 2023)Introduction: To calculate the number of days patients with terminal non-small cell lung cancer (NSCLC) spent at home in the last 3 months of life, and to identify factors that predict a lower proportion of days at ... -
Days at home in the last three months of life: patterns-of-care analysis in patients with non-small cell lung cancer
(Peer reviewed; Journal article, 2023)Introduction: To calculate the number of days patients with terminal non small cell lung cancer (NSCLC) spent at home in the last 3 months of life, and to identify factors that predict a lower proportion of days at home. ... -
Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids
(Peer reviewed; Journal article, 2021-04)The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ... -
Digital Image Analysis of Ki-67 Stained Tissue Microarrays and Recurrence in Tamoxifen-Treated Breast Cancer Patients
(Peer reviewed; Journal article, 2020-07)Purpose: The proliferation marker Ki-67 has been used as a prognostic marker to separate low- and high-risk breast cancer subtypes and guide treatment decisions for adjuvant chemotherapy. The association of Ki-67 with ... -
Effects of replacing PSA with Stockholm3 for diagnosis of clinically significant prostate cance in a health care system – the Stavanger Experience
(Peer reviewed; Journal article, 2020-08)Objective To describe early experience of replacing PSA with Stockholm3 for detection of prostate cancer in primary care. Design and methods Longitudinal observations, comparing outcome measures before and after the ... -
Elevated microsatellite alterations at selected tetranucleotides in early-stage colorectal cancers with and without high-frequency microsatellite instability: same, same but different?
(Journal article; Peer reviewed, 2016-02)Microsatellite instability (MSI) is associated with better prognosis in colorectal cancer (CRC). Elevated microsatellite alterations at selected tetranucleotides (EMAST) is a less-understood form of MSI. Here, we aim to ... -
Emerging Role of Epigenetic Alterations as Biomarkers and Novel Targets for Treatments in Pancreatic Ductal Adenocarcinoma
(Peer reviewed; Journal article, 2022-01)Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with limited treatment options. Emerging evidence shows that epigenetic alterations are present in PDAC. The changes are potentially reversible and therefore ... -
High-Grade Cervical Intraepithelial Neoplasia (CIN) Associates with Increased Proliferation and Attenuated Immune Signaling
(Peer reviewed; Journal article, 2021-12)Implementation of high-risk human papilloma virus (HPV) screening and the increasing proportion of HPV vaccinated women in the screening program will reduce the percentage of HPV positive women with oncogenic potential. ... -
Improved Machine Learning-Based Predictive Models for Breast Cancer Diagnosis
(Peer reviewed; Journal article, 2022-03)Breast cancer death rates are higher than any other cancer in American women. Machine learning-based predictive models promise earlier detection techniques for breast cancer diagnosis. However, making an evaluation for ... -
Is There a Trojan Horse to Aggressive Pancreatic Cancer Biology? A Review of the Trypsin-PAR2 Axis to Proliferation, Early Invasion, and Metastasis
(Peer reviewed; Journal article, 2020-02)Purpose: Pancreatic cancer is one of the most lethal of solid tumors and is associated with aggressive cancer biology. The purpose is to review the role of trypsin and effect on molecular and cellular processes potentially ... -
Laparoscopic rectal cancer resection yields comparable clinical and oncological results with shorter hospital stay compared to open access: a 5-year national cohort. aparoscopic rectal cancer resection yields comparable clinical and oncological results with shorter hospital stay compared to open access: a 5-year national cohort
(Peer reviewed; Journal article, 2023)Purpose Although widely applied, the results following laparoscopic rectal resection (LRR) compared to open rectal resection (ORR) are still debated. The aim of this study was to assess clinical short- and long-term results ... -
Liquid Biopsies in Solid Cancers: Implementation in a Nordic Healthcare System
(Peer reviewed; Journal article, 2021-04)Liquid biopsies have emerged as a potential new diagnostic tool, providing detailed information relevant for characterization and treatment of solid cancers. We here present an overview of current evidence supporting the ... -
Long-term recovery after colorectal cancer surgery among the old: a qualitative study
(Peer reviewed; Journal article, 2023-04)Background Colorectal cancer is the third most frequently diagnosed cancer worldwide, disproportionally affecting older people. With modern treatment, older people are surviving cancer treatment and recovery. However, ... -
Metabolic flux analysis of 3D spheroids reveals significant differences in glucose metabolism from matched 2D cultures of colorectal cancer and pancreatic ductal adenocarcinoma cell lines
(Peer reviewed; Journal article, 2022-05)Background Most in vitro cancer cell experiments have been performed using 2D models. However, 3D spheroid cultures are increasingly favored for being more representative of in vivo tumor conditions. To overcome the ...