• Artificial intelligence in dry eye disease 

      Storås, Andrea Marheim; Strumke, Inga; Riegler, Michael Alexander; Grauslund, Jakob; Hammer, Hugo Lewi; Yazidi, Anis; Halvorsen, Pål; Gundersen, Kjell Gunnar; Utheim, Tor Paaske; Jackson, Catherine Joan (Journal article, 2022-01)
      Dry eye disease (DED) has a prevalence of between 5 and 50%, depending on the diagnostic criteria used and population under study. However, it remains one of the most underdiagnosed and undertreated conditions in ophthalmology. ...
    • The association between visual display terminal use and dry eye: a review 

      Fjærvoll, Haakon Kristoffer Olsen; Fjærvoll, Ketil Andreas Olsen; Magnø, Morten Scherven; Moschowits, Emily; Vehof, Jelle; Dartt, Darlene A.; Utheim, Tor Paaske (Peer reviewed; Journal article, 2021-10)
      Background Dry eye disease (DED) is a multifactorial disease of the tear film and ocular surface. It causes ocular symptoms, reduced quality of life and a considerable economic burden on society. Prolonged use of visual ...
    • Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels 

      Landsend, Erlend Christoffer Sommer; Olafsson, Jonatan; Lai, Xiaoran; Aass, Hans Christian Dalsbotten; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Purpose. To investigate the changes in the tear cytokine profile of patients with meibomian gland dysfunction (MGD) treated with eyelid warming and to correlate these changes with clinical parameters for dry eye disease ...
    • A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review 

      Hynnekleiv, Leif; Magnø, Morten Schjerven; Moschowits, Emily; Tønseth, Kim Alexander; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2023)
      Dry eye disease (DED) is a highly prevalent and debilitating condition. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan that has a long history as a safe and effective DED treatment. HA is frequently used ...
    • Hot towels: The bedrock of Meibomian gland dysfunction treatment – A review 

      Magnø, Morten Schjerven; Olafsson, Jonatan; Beining, Marie Wangen; Moschowits, Emily; Lagali, Neil Satish; Wolffsohn, James S.; Craig, Jennifer P.; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Background Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ...
    • In silico discovery of blood cell macromolecular associations 

      Gautvik, Kaare M; Sachse, Daniel; Hinton, Alexandra C.; Olstad, Ole Kristoffer; Kiel, Douglas P.; Hsu, Yi-Hsiang; Utheim, Tor Paaske; Lary, Christine W.; Reppe, Sjur (Journal article, 2022)
      Background Physical molecular interactions are the basis of intracellular signalling and gene regulatory networks, and comprehensive, accessible databases are needed for their discovery. Highly correlated transcripts may ...
    • Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future 

      Fineide, Fredrik; Magnø, Morten Schjerven; Khan, Ayyad Ahmad Zartasht; Chen, Xiangjun; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2023)
      Dry eye disease is a highly prevalent condition, which can substantially impair quality of life, work productivity, and vision. It is considered an inflammatory disease and the most common cause is meibomian gland dysfunction. ...
    • Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future 

      Fineide, Fredrik; Magnø, Morten Schjerven; Khan, Ayyad Ahmad Zartasht; Chen, Xiangjun; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2023)
      Dry eye disease is a highly prevalent condition, which can substantially impair quality of life, work productivity, and vision. It is considered an inf lammatory disease and the most common cause is meibomian gland ...
    • Predicting an unstable tear film through artificial intelligence 

      Fineide, Fredrik; Storås, Andrea; Chen, Xiangjun; Magnø, Morten Schjerven; Yazidi, Anis; Riegler, Michael; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Dry eye disease is one of the most common ophthalmological complaints and is defined by a loss of tear film homeostasis. Establishing a diagnosis can be time-consuming, resource demanding and unpleasant for the patient. ...
    • Review on the possible pathophysiological mechanisms underlying visual display terminal-associated dry eye disease 

      Fjærvoll, Ketil Andreas Olsen; Fjærvoll, Haakon Kristoffer Olsen; Magnø, Morten Scherven; Tellefsen Nøland, Sara Julie Maria; Dartt, Darlene Ann; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Background Visual display terminal (VDT) use is a key risk factor for dry eye disease (DED). Visual display terminal (VDT) use reduces the blink rate and increases the number of incomplete blinks. However, the exact ...
    • Role of stem cells in regenerative treatment of dry eye disease caused by lacrimal gland dysfunction 

      Jackson, Catherine Joan; Naqvi, Maria; Gundersen, Kjell Gunnar; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      An ageing population and increased screen use in younger people have contributed to a rise in incidence of dry eye disease (DED). Quality of life can be significantly affected by DED, with patients experiencing eye dryness, ...
    • Seasonal variations in presenting symptoms and signs of dry eye disease in Norway 

      Eidet, Jon Roger; Chen, Xiangjun; Ræder, Sten; Badian, Reza; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      The study investigated the seasonal variations of presenting symptoms and signs of dry eye disease (DED) in Norway. 652 consecutive DED patients examined between August 2012 and May 2015 in Oslo, Norway, were included. ...
    • Topical glaucoma medications – Clinical implications for the ocular surface 

      Fineide, Fredrik; Lagali, Neil Satish; Adil, Muhammed Yasin; Arita, Reiko; Kolko, Miriam; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to reduce intraocular pressure remains the mainstay treatment. These eye drops frequently contain preservatives designed to ensure sterility ...
    • Video display terminal use and dry eye: preventive measures and future perspectives 

      Kamøy, Bjørnar; Magnø, Morten Scherven; Tellefsen Nøland, Sara Julie Maria; Moe, Morten Carsten; Petrovski, Goran; Vehof, Jelle; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      Background Dry eye disease (DED) is a common cause of ocular pain and discomfort. Dry eye disease (DED) stems from a loss-of-tear film homeostasis and is frequently seen in video display terminal (VDT) users. Video display ...