• An amplified derepression controller with multisite inhibition and positive feedback 

      Drobac, Gorana; Waheed, Qaiser; Heidari, Behzad; Ruoff, Peter (Peer reviewed; Journal article, 2021-03)
      How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. ...
    • Anaerobic Fungi: Past, Present, and Future 

      Hess, Matthias; Paul, Shyam S.; Puniya, Anil K.; van der Giezen, Mark; Shaw, Claire; Edwards, Joan E.; Fliegerova, Katerina (Peer reviewed; Journal article, 2020-10)
      Anaerobic fungi (AF) play an essential role in feed conversion due to their potent fiber degrading enzymes and invasive growth. Much has been learned about this unusual fungal phylum since the paradigm shifting work of ...
    • The Asgard Archaeal-Unique Contribution to Protein Families of the Eukaryotic Common Ancestor Was 0.3% 

      Knopp, Michael; Stockhorst, Simon; van der Giezen, Mark; Garg, Sriram G; Gould, Sven B (Peer reviewed; Journal article, 2021-04)
      The identification of the asgard archaea has fueled speculations regarding the nature of the archaeal host in eukaryogenesis and its level of complexity prior to endosymbiosis. Here, we analyzed the coding capacity of 150 ...
    • Capturing CO2 from Biogas Plants 

      Li, Hailong; Tan, Y; Ditaranto, Mario; Yan, Jinying; Yu, Zhixin (Peer reviewed; Journal article, 2017-07)
      As a renewable energy, biogas produced from anaerobic digestion and landfill is playing a more and more important role in the energy market. Capturing CO2 from biogas can result in a negative CO2 emission. Depending on how ...
    • Characterisation of a novel cold-adapted calcium- activated transglutaminase: implications for medicine and food processing 

      Álvarez, Rebeca García; Karki, Pralav; Langleite, Ida Elise; Bakksjø, Ragna-Johanne; Eichacker, Lutz Andreas; Furnes, Clemens (Peer reviewed; Journal article, 2020-03)
      Transglutaminases are a family of enzymes that catalyse the cross‐linking of proteins by forming covalent bonds between lysine and glutamine residues in various polypeptides. Cross‐linking reactions are involved in blood ...
    • Development of a constitutive and an auto-inducible high-yield expression system for recombinant protein production in the microalga Nannochloropsis oceanica 

      de Grahl, Imke; Rout, Sweta Suman; Maple-Grødem, Jodi; Reumann, Sigrun (Peer reviewed; Journal article, 2020-09)
      Photoautotrophic microalgae offer a great potential as novel hosts for efficient recombinant protein production. Nannochloropsis oceanica produces an extraordinarily high content of polyunsaturated fatty acids, and its ...
    • Evolutionary relationships within the lamioid tribe Synandreae (Lamiaceae) based on multiple low-copy nuclear loci 

      Roy, Tilottama; Catlin, Nathan S.; Garner, Drake M.G.; Cantino, Philip D.; Scheen, Anne-Cathrine; Lindqvist, Charlotte (Journal article; Peer reviewed, 2016-07)
      The subfamily Lamioideae (Lamiaceae) comprises ten tribes, of which only Stachydeae and Synandreae include New World members. Previous studies have investigated the phylogenetic relationships among the members of Synandreae ...
    • The free-living flagellate Paratrimastix pyriformis uses a distinct mitochondrial carrier to balance adenine nucleotide pools 

      Zítek, Justyna; King, Martin S.; Peña-Diaz, Priscila; Pyrihova, Eva; King, Alannah C.; Kunji, Edmund R.S.; Hampl, Vladimír (Peer reviewed; Journal article, 2023)
      Paratrimastix pyriformis is a free-living flagellate thriving in low-oxygen freshwater sediments. It belongs to the group Metamonada along with human parasites, such as Giardia and Trichomonas. Like other metamonads, P. ...
    • Frequency switching between oscillatory homeostats and the regulation of p53 

      Ruoff, Peter; Nishiyama, Nobuaki (Peer reviewed; Journal article, 2020-05)
      Homeostasis is an essential concept to understand the stability of organisms and their adaptive behaviors when coping with external and internal assaults. Many hormones that take part in homeostatic control come in ...
    • Historical Spruce Abundance in Central Europe: A Combined Dendrochronological and Palynological Approach 

      Seim, Andrea; Marquer, Laurent; Bisson, Ugo; Hofmann, Jutta; Herzig, Franz; Kontic, Raymond; Lechterbeck, Jutta; Muigg, Bernhard; Neyses-Eiden, Mechthild; Rzepecki, Andreas; Rösch, Manfred; Walder, Felix; Weidemüller, Julia; Tegel, Willy (Peer reviewed; Journal article, 2022)
      Spruce is the most cultivated tree species in modern forestry in Central Europe, since it has the ability to grow on many soil types with profitable biomass accumulation. However, even-aged and uniform spruce forests are ...
    • Homeostatic controllers compensating for growth and perturbations 

      Ruoff, Peter; Agafonov, Oleg; Tveit, Daniel Myklatun; Thorsen, Kristian; Drengstig, Tormod (Journal article; Peer reviewed, 2019-08)
      Cells and organisms have developed homeostatic mechanisms which protect them against a changing environment. How growth and homeostasis interact is still not well understood, but of increasing interest to the molecular and ...
    • Human scent as a first-line defense against disease 

      Gordon, Amy R.; Lundström, Johan N.; Kimball, Bruce A.; Karshikoff, Bianka; Sorjonen, Kimmo; Axelsson, John; Lekander, Mats; Olsson, Mats J. (Peer reviewed; Journal article, 2023)
      Individuals may have a different body odor, when they are sick compared to healthy. In the non-human animal literature, olfactory cues have been shown to predict avoidance of sick individuals. We tested whether the mere ...
    • In silico investigations of intratumoral heterogeneous interstitial fluid pressure 

      Waldeland, Jahn Otto; Gaustad, Jon-Vidar; Rofstad, Einar K; Evje, Steinar (Peer reviewed; Journal article, 2021-06)
      Recent preclinical studies have shown that interstitial fluid pressure (IFP) within tumors can be heterogeneous Andersen et al. (2019). In that study tumors of two xenograft models, respectively, HL-16 cervical carcinoma ...
    • Kinetics and mechanisms of catalyzed dual-E (antithetic) controllers 

      Waheed, Qaiser; Zhou, Huimin; Ruoff, Peter (Peer reviewed; Journal article, 2022)
      Homeostasis plays a central role in our understanding how cells and organisms are able to oppose environmental disturbances and thereby maintain an internal stability. During the last two decades there has been an increased ...
    • Late Neolithic Agriculture in Temperate Europe — A Long-Term Experimental Approach 

      Rösch, Manfred; Biester, Harald; Bogenrieder, Arno; Eckmeier, Eileen; Ehrmann, Otto; Gerlach, Renate; Hall, Mathias; Hartkopf-Fröder, Christoph; Herrmann, Ludger; Kury, Birgit; Lechterbeck, Jutta; Schier, Wolfram; Schulz, Erhard (Journal article; Peer reviewed, 2017-02)
      Long-term slash-and-burn experiments, when compared with intensive tillage without manuring, resulted in a huge data set relating to potential crop yields, depending on soil quality, crop type, and agricultural measures. ...
    • Mimicking orchids lure bees from afar with exaggerated ultraviolet signals 

      Scaccabarozzi, Daniela; Lunau, Klaus; Guzzetti, Lorenzo; Cozzolino, Salvatore; Dyer, Adrian G.; Tommasi, Nicola; Biella, Paolo; Galimberti, Andrea; Labra, Massimo; Bruni, Ilaria; Pattarini, Giorgio; Brundrett, Mark; Gagliano, Monica (Peer reviewed; Journal article, 2023-01)
      Flowers have many traits to appeal to pollinators, including ultraviolet (UV) absorbing markings, which are well-known for attracting bees at close proximity (e.g., <1 m). While striking UV signals have been thought to ...
    • Molecular Dynamics Simulations of a Chimeric Androgen Receptor Protein (SPARKI) Confirm the Importance of the Dimerization Domain on DNA Binding Specificity 

      Bagherpoor Helabad, Mahdi; Volkenandt, Senta; Imhof, Petra (Peer reviewed; Journal article, 2020-01)
      The DNA binding domains of Androgen/Glucocorticoid receptors (AR/GR), members of class I steroid receptors, bind as a homo-dimer to a cis-regulatory element. These response elements are arranged as inverted repeat (IR) of ...
    • Multi-targeted trehalose-6-phosphate phosphatase I harbors a novel peroxisomal targeting signal 1 and is essential for flowering and development 

      Kataya, Amr Ramzy Abass; ElShobaky, Ahmed; Heidariahootapeh, Behzad; Nemie-Feyissa, Dugassa; Thelen, Jay J.; Lillo, Cathrine (Peer reviewed; Journal article, 2020-04)
      A putative, non-canonical peroxisomal targeting signal type 1 (PTS1) Pro-Arg-Met > was identified in the extreme C-terminus of trehalose-6-phosphate phosphatase (TPP)I. TPP catalyzes the final step of trehalose synthesis, ...
    • Nutraceutical productions from microalgal derived compounds via circular bioeconomy perspective 

      Huy, Menghour; Vatland, Ann Kristin; Kumar, Gopalakrishnan (Peer reviewed; Journal article, 2021-03)
      Circular bioeconomy has become a sustainable business model for commercial production that promises to reuse, recycle & recover while considering less environmental footprints in nutraceutical industries. Microalgae ...
    • Pinpointing regulatory protein phosphatase 2A subunits involved in beneficial symbiosis between plants and microbes 

      Averkina, Irina Orestovna; Harris, Muhammad; Asare, Edward Ohene; Hourdin, Bérénice; Paponov, Ivan; Lillo, Cathrine (Peer reviewed; Journal article, 2021-04)
      Background PROTEIN PHOSPHATASE 2A (PP2A) expression is crucial for the symbiotic association between plants and various microbes, and knowledge on these symbiotic processes is important for sustainable agriculture. Here ...