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dc.contributor.authorZhu, Changbo
dc.contributor.authorChen, Yaqing
dc.contributor.authorMüller, Hans-Georg
dc.contributor.authorWang, Jane-Ling
dc.contributor.authorO'Muircheartaigh, Jonathan
dc.contributor.authorBruchhage, Muriel Marisa Katharina
dc.contributor.authorDeoni, Sean
dc.date.accessioned2023-09-12T09:14:12Z
dc.date.available2023-09-12T09:14:12Z
dc.date.created2023-04-20T12:30:04Z
dc.date.issued2023-03
dc.identifier.citationZhu, C., Chen, Y., Müller, H-G., Wang, J-L., O'Muircheartaigh, J. Bruchhage,M. & Deoni, S. (2023) Trajectories of brain volumes in young children are associated with maternal education. Human Brain Mapping, 44(8), 3168-3179en_US
dc.identifier.issn1065-9471
dc.identifier.urihttps://hdl.handle.net/11250/3088825
dc.description.abstractBrain growth in early childhood is reflected in the evolution of proportional cerebrospinal fluid volumes (pCSF), grey matter (pGM), and white matter (pWM). We study brain development as reflected in the relative fractions of these three tissues for a cohort of 388 children that were longitudinally followed between the ages of 18 and 96 months. We introduce statistical methodology (Riemannian Principal Analysis through Conditional Expectation, RPACE) that addresses major challenges that are of general interest for the analysis of longitudinal neuroimaging data, including the sparsity of the longitudinal observations over time and the compositional structure of the relative brain volumes. Applying the RPACE methodology, we find that longitudinal growth as reflected by tissue composition differs significantly for children of mothers with higher and lower maternal education levels.en_US
dc.language.isoengen_US
dc.publisherJohn Wiley & Sons Ltd.en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.subjectbarns hjerneen_US
dc.subjecthjerneveksten_US
dc.titleTrajectories of brain volumes in young children are associated with maternal educationen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© 2023 The Authorsen_US
dc.subject.nsiVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752en_US
dc.source.pagenumber3168-3179en_US
dc.source.volume44en_US
dc.source.journalHuman Brain Mappingen_US
dc.source.issue8en_US
dc.identifier.doi10.1002/hbm.26271
dc.identifier.cristin2142112
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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