Blar i Publikasjoner fra CRIStin på forfatter "Omdal, Roald"

Viser treff 1-13 av 13

    • Anti-HMGB1 auto-Abs influence fatigue in patients with Crohn’s disease 

      Kvivik, Ingeborg; Grimstad, Tore Bjørn; Jonsson, Grete; Kvaløy, Jan T.; Omdal, Roald (Peer reviewed; Journal article, 2021-05)
      Fatigue is common in all chronic inflammatory and autoimmune diseases. A conceptual model for understanding the biological basis of fatigue describes it as being a part of the sickness behaviour response generated by ...

    • Determination of lower cut-off levels of adalimumab associated with biochemical remission in Crohn's disease 

      Carlsen, Arne; Omdal, Roald; Karlsen, Lars Normann; Kvaløy, Jan Terje; Aabakken, Lars; Steinsbø, Øyvind; Bolstad, Nils; Warren, David; Lundin, Knut Erik Aslaksen; Grimstad, Tore (Journal article; Peer reviewed, 2019-08)
      Background and Aim: Adalimumab is administered and dosed using a standardized treatment regimen. Although therapeutic drug monitoring (TDM) may help optimize treatment efficacy, the lower cut-off concentration of adalimumab ...

    • Fatigue in primary Sjögren's syndrome: A proteomic pilot study of cerebrospinal fluid 

      Larssen, Eivind; Brede, Cato; Hjelle, Anne; Tjensvoll, Anne Bolette; Norheim, Katrine Brække; Bårdsen, Kjetil; Jonsdottir, Kristin; Ruoff, Peter; Omdal, Roald; Nilsen, Mari Mæland (Peer reviewed; Journal article, 2019-05)
      Objectives: Fatigue is a frequent and often disabling phenomenon that occurs in patients with chronic inflammatory and immunological diseases, and the underlying biological mechanisms are largely unknown. Because fatigue ...

    • Fatigue: a frequent and biologically based phenomenon in newly diagnosed celiac disease 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Peer reviewed; Journal article, 2022)
      Fatigue is increasingly recognized as a major complaint in patients with chronic inflammatory and autoimmune diseases. Although fatigue is assumed to represent a significant problem in celiac disease, existing knowledge ...

    • Heat shock proteins and chronic fatigue in primary Sjögren's syndrome 

      Bårdsen, Kjetil; Mæland, Mari; Kvaløy, Jan Terje; Norheim, Katrine Brække; Jonsson, Grete; Omdal, Roald (Journal article; Peer reviewed, 2016-01)
      Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When ...

    • Heat-shock protein 90α in plasma reflects severity of fatigue in patients with Crohn’s disease 

      Grimstad, Tore; Kvivik, Ingeborg; Kvaløy, Jan Terje; Aabakken, Lars; Omdal, Roald (Journal article; Peer reviewed, 2019-10)
      Heat-shock proteins (HSPs) are evolutionarily conserved proteins with important cellular homeostasis functions during harmful conditions, including inflammation. Some HSPs are secreted extracellularly and act on distant ...

    • High mobility group box 1 and a network of other biomolecules influence fatigue in patients with Crohn’s disease 

      Kvivik, Ingeborg; Grimstad, Tore Bjørn; Bårdsen, Kjetil; Jonsson, Grete; Kvaløy, Jan Terje; Omdal, Roald (Peer reviewed; Journal article, 2023-06)
      Background Fatigue is common in patients with chronic inflammatory and autoimmune diseases, often with a severe impact on the patient’s daily life. From a biological point of view, fatigue can be regarded as an element ...

    • Interleukin-1-related activity and hypocretin-1 in cerebrospinal fluid contribute to fatigue in primary Sjögren's syndrome 

      Bårdsen, Kjetil; Brede, Cato; Kvivik, Ingeborg; Kvaløy, Jan Terje; Jonsdottir, Kristin; Tjensvoll, Anne Bolette; Ruoff, Peter; Omdal, Roald (Peer reviewed; Journal article, 2019)
      Background Fatigue is a common and sometimes debilitating phenomenon in primary Sjögren’s syndrome (pSS) and other chronic inflammatory diseases. We aimed to investigate how IL-1 β-related molecules and the neuropeptide ...

    • Less, but not gone—gluten-free diet effects on fatigue in celiac disease: a prospective controlled study 

      Skjellerudsveen, Berit Mære; Omdal, Roald; Hetta, Anne Kristine; Kvaløy, Jan Terje; Aabakken, Lars; Skoie, Inger Marie; Grimstad, Tore Bjørn (Peer reviewed; Journal article, 2023)
      Introduction: Fatigue is a frequent complaint in patients with celiac disease. A gluten-free diet is the only established treatment for celiac disease, but how this diet influences fatigue is uncertain. We aimed to investigate ...

    • Nasal and salivary pepsin as a biomarker for gastro-esophageal reflux in chronic rhinosinusitis 

      Katle, Elin-Johanne; Hatlebakk, Jan Gunnar; Omdal, Roald; Kvaløy, Jan Terje; Steinsvåg, Sverre Karmhus (Journal article; Peer reviewed, 2019-03)
      Background: Gastro-esophageal reflux (GER) may be a contributing factor for some patients with chronic rhinosinusitis (CRS). The aim of the present study was to investigate if Peptest, an immunoassay for pepsin detection, ...

    • Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren’s syndrome 

      Tjensvoll, Anne Bolette; Lauvsnes, Maria Boge; Zetterberg, Henrik; Kvaløy, Jan Terje; Kvivik, Ingeborg; Maroni, Stian; Greve, Ole Jacob; Beyer, Mona K.; Hirohata, Shunsei; Putterman, Chaim; Alves, Guido Werner; Harboe, Erna; Blennow, Kaj; Gøransson, Lasse; Omdal, Roald (Peer reviewed; Journal article, 2020-10)
      Background To test the hypothesis that neurofilament light (NfL) in CSF is a biomarker of CNS involvement in patients with systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS), we measured NfL in CSF ...

    • Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein 

      Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato (Peer reviewed; Journal article, 2021-06)
      Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...

    • Thyroidectomy Versus Medical Management for Euthyroid Patients With Hashimoto Disease and Persisting Symptoms: A Randomized Trial 

      Guldvog, Ivar; Reitsma, Laurens Cornelus; Johnsen, Lene Cathrin; Lauzike, Andromeda; Gibbs, Charlotte Christine; Carlsen, Eivind; Lende, Tone Hoel; Narvestad, Jon; Omdal, Roald; Kvaløy, Jan Terje; Hoff, Geir; Bernklev, Tomm; Søiland, Håvard (Peer reviewed; Journal article, 2019-04)
      Background: Hashimoto disease is a chronic autoimmune thyroiditis. Despite adequate hormone substitution, some patients have persistent symptoms that may be the result of immunologic pathophysiology. Objective: To ...