• 6 min walk test is a strong independent predictor of death in outpatients with heart failure 

      Grundtvig, Morten; Eriksen-Volnes, Torfinn; Ørn, Stein; Slind, Eva Kjøl; Gullestad, Lars (Peer reviewed; Journal article, 2020)
      Aims The aim of this study was to examine the prognostic value of the 6 min walk test (6MWT) in a large cohort of outpatients with heart failure. Methods and results A total of 5519 outpatients with heart failure from ...
    • Determinants of interindividual variation in exercise-induced cardiac troponin i levels 

      Bjørkavoll-Bergseth, Magnus; Erevik, Christine Bjørkvik; Kleiven, Øyunn; Eijsvogels, Thijs M. H.; Skadberg, Øyvind; Frøysa, Vidar; Wiktorski, Tomasz; Auestad, Bjørn; Edvardsen, Thor; Aakre, Kristin Moberg; Ørn, Stein (Peer reviewed; Journal article, 2021-08)
      Background Postexercise cardiac troponin levels show considerable interindividual variations. This study aimed to identify the major determinants of this postexercise variation in cardiac troponin I (cTnI) following 3 ...
    • Endurance exercise training volume is not associated with progression of coronary artery calcification 

      Kleiven, Øyunn; Bjørkavoll-Bergseth, Magnus; Omland, Torbjørn; Aakre, Kristin Moberg; Frøysa, Vidar; Erevik, Christine B.; Greve, Ole Jacob; Melberg, Tor Harald; Auestad, Bjørn Henrik; Skadberg, Øyvind; Edvardsen, Thor; Ørn, Stein (Peer reviewed; Journal article, 2020-02)
      Background Recent cross‐sectional studies have suggested a dose‐dependent relationship between lifelong exposure to physical activity and the burden of calcified coronary artery disease (CAD). No longitudinal studies have ...
    • Exercise-Induced Cardiac Troponin Elevations: From Underlying Mechanisms to Clinical Relevance 

      Aengevaeren, Vincent L; Baggish, Aaron L; Chung, Eugene H.; George, Keith; Kleiven, Øyunn; Mingels, Alma M. A.; Ørn, Stein; Shave, Rob E.; Thompson, Paul; Eijsvogels, Thijs M. H. (Peer reviewed; Journal article, 2021)
      Serological assessment of cardiac troponins (cTn) is the gold standard to assess myocardial injury in clinical practice. A greater magnitude of acutely or chronically elevated cTn concentrations is associated with lower ...
    • Occult obstructive coronary artery disease is associated with prolonged cardiac troponin elevation following strenuous exercise 

      Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-06)
      Background Sudden cardiac death among middle-aged recreational athletes is predominantly due to myocardial ischaemia. This study examined whether measuring cardiac troponin I and T (cTnI and cTnT) after strenuous exercise ...
    • Race duration and blood pressure are major predictors of exercise-induced cardiac troponin elevation 

      Kleiven, Øyunn; Omland, Torbjørn; Skadberg, Øyvind; Melberg, Tor Harald; Bjørkavoll-Bergseth, Magnus; Auestad, Bjørn Henrik; Bergseth, Rolf; Greve, Ole Jacob; Aakre, Kristin Moberg; Ørn, Stein (Journal article; Peer reviewed, 2019-02)
      Background The underlying mechanisms of the exercise-induced increase in cardiac troponins (cTn) are poorly understood. The aim of this study was to identify independent determinants of exercise-induced cTn increase in a ...
    • The relationship between Fibroblast Growth Factor 23 (FGF23) and cardiac MRI findings following primary PCI in patients with acute first time STEMI 

      Thorsen, Inga Strand; Gøransson, Lasse Gunnar; Ueland, Thor; Aukrust, Pål; Manhenke, Cord A; Skadberg, Øyvind; Jonsson, Grete; Ørn, Stein (Peer reviewed; Journal article, 2021-04)
      Background Fibroblast growth factor 23 (FGF23) is a regulator of mineral metabolism, that has been linked to myocardial remodeling including development of left ventricular (LV) hypertrophy and myocardial fibrosis. The ...