• A Longitudinal Study of Neurocognition in Dementia with Lewy Bodies Compared to Alzheimer`s Disease 

      Breitve, Monica Haraldseid; Chwiszczuk, Luiza; Hynninen, Kia Minna; Brønnick, Kolbjørn Selvåg; Auestad, Bjørn Henrik; Aarsland, Dag; Rongve, Arvid (Journal article; Peer reviewed, 2018-03)
      Introduction: There are relatively few longitudinal studies on the differences in cognitive decline between Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB), and the majority of existing studies have suboptimal ...
    • Combinatory microRNA serum signatures as classifiers of Parkinson's disease 

      Patil, Ketan S.; Basak, Indranil; Dalen, Ingvild; Hoedt, Esthelle; Lange, Johannes; Lunde, Kristin Aaser; Liu, Ying; Tysnes, Ole-Bjørn; Forsgren, Lars; Aarsland, Dag; Neubert, Thomas A.; Larsen, Jan Petter; Alves, Guido Werner; Møller, Simon Geir (Journal article; Peer reviewed, 2019-04)
      As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ...
    • Evolution of impulsive–compulsive behaviors and cognition in Parkinson’s disease 

      Erga, Aleksander Hagen; Alves, Guido Werner; Tysnes, Ole-Bjørn; Pedersen, Kenn Freddy (Journal article; Peer reviewed, 2019-10)
      The longitudinal course of ICBs in patients with Parkinson’s disease (PwP) relative to controls has not been explored as of yet. The aim of this study is to determine the frequency, evolution and associated cognitive and ...
    • Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease 

      Borda, Miguel Germán; Sønnesyn, Hogne; Steves, Claire J.; Vik-Mo, Audun Osland; Perez-Zepeda, Mario Ulises; Årsland, Dag (Journal article; Peer reviewed, 2019-04)
      Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). Methods: This is a secondary ...
    • Genetic risk of Parkinson disease and progression: An analysis of 13 longitudinal cohorts 

      Iwaki, Hirotaka; Blauwendraat, Cornelis; Leonard, Hampton L.; Liu, Ganqiang; Maple-Grødem, Jodi; Corvol, Jean-Christophe; Pihlstrøm, Lasse; van Nimwegen, Marlies; Hutten, Samantha J.; Nguyen, Khanh-Dung H.; Rick, Jacqueline; Eberly, Shirley; Faghri, Faraz; Auinger, Peggy; Scott, Kirsten M.; Wijeyekoon, Ruwani; van Deerlin, Vivianna M.; Hernandez, Dena G.; Day-Williams, Aaron G.; Brice, Alexis; Alves, Guido Werner; Noyce, Alastair J.; Tysnes, Ole-Bjørn; Evans, Jonathan R.; Breen, David P.; Estrada, Karol; Wegel, Claire E.; Danjou, Fabrice; Simon, David K.; Ravina, Bernard; Toft, Mathias; Heutink, Peter; Bloem, Bastiaan R.; Weintraub, Daniel; Barker, Roger A.; Williams-Gray, Caroline H.; van de Warrenburg, Bart P.; van Hilten, Jacobus J.; Scherzer, Clemens R.; Singleton, Andrew B.; Nalls, Mike A. (Journal article; Peer reviewed, 2019-08)
      Objective To determine if any association between previously identified alleles that confer risk for Parkinson disease and variables measuring disease progression. Methods We evaluated the association between 31 risk ...
    • Kynurenines, Neuropsychiatric Symptoms, and Cognitive Prognosis in Patients with Mild Dementia 

      Solvang, Stein-Erik Hafstad; Nordrehaug, Jan Erik; Aarsland, Dag; Lange, Johannes; Ueland, Per Magne; McCann, Adrian; Midttun, Øivind; Tell, Grethe S.; Melvær, Giil Lasse (Journal article; Peer reviewed, 2019-09)
      Introduction: Circulating tryptophan (Trp) and its downstream metabolites, the kynurenines, are potentially neuroactive. Consequently, they could be associated with neuropsychiatric symptoms and cognitive prognosis in ...
    • The value of cerebrospinal fluid alpha-synuclein and the tau/alpha-synuclein ratio for diagnosis of neurodegenerative disorders with Lewy pathology 

      Førland, Marthe Gurine; Tysnes, Ole-Bjørn; Aarsland, Dag; Maple-Grødem, Jodi; Pedersen, Kenn Freddy; Alves, Guido Werner; Lange, Johannes (Journal article; Peer reviewed, 2019-07)
      Background and purpose Parkinson's disease (PD), dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) are three of the most common neurodegenerative disorders. Up to 20% of these patients have the wrong diagnosis, ...