dc.contributor.author | Borda, Miguel Germán | |
dc.contributor.author | Sønnesyn, Hogne | |
dc.contributor.author | Steves, Claire J. | |
dc.contributor.author | Vik-Mo, Audun Osland | |
dc.contributor.author | Perez-Zepeda, Mario Ulises | |
dc.contributor.author | Årsland, Dag | |
dc.date.accessioned | 2020-03-12T08:58:22Z | |
dc.date.available | 2020-03-12T08:58:22Z | |
dc.date.created | 2019-11-12T10:45:24Z | |
dc.date.issued | 2019-04 | |
dc.identifier.citation | Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease. Dementia and geriatric cognitive disorders extra, 9(1), pp. 176–183 | nb_NO |
dc.identifier.issn | 1664-5464 | |
dc.identifier.uri | http://hdl.handle.net/11250/2646493 | |
dc.description.abstract | Introduction: The aim of the study is to describe the frequency of frailty in people with a new diagnosis of mild dementia due to Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB).
Methods: This is a secondary analysis of the Dementia Study of Western Norway (Demvest). For this study, we analysed a sample of 186 patients, 116 with AD and 70 with DLB. Subjects were included at a time in which mild dementia was diagnosed according to consensus criteria after comprehensive standardized assessment. Frailty was evaluated retrospectively using a frailty index generated from existing data. The cut-off value used to classify an older adult as frail was 0.25.
Results: The prevalence of frailty was 25.81% (n = 48). In the DLB group, 37.14% (n = 26) were classified as frail, compared to 18.97% (n = 22) of those with AD (p < 0.001). The adjusted multivariate analysis revealed an OR of 2.45 (1.15–5.23) for being frail in those with DLB when using AD as the reference group.
Conclusion: Frailty was higher than expected in both types of dementia. The prevalence of frailty was higher in those with DLB compared to AD. This new finding underscores the need for a multi-systems approach in both dementias, with a particular focus on DLB. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | S. Karger AG | nb_NO |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/deed.no | * |
dc.subject | demens | nb_NO |
dc.subject | Alzheimers | nb_NO |
dc.subject | demens med Lewy-legemer | nb_NO |
dc.title | Frailty in Older Adults with Mild Dementia: Dementia with Lewy Bodies and Alzheimer’s Disease | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.rights.holder | © 2019 The Author(s) | nb_NO |
dc.subject.nsi | VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Neurology: 752 | nb_NO |
dc.source.pagenumber | 176–183 | nb_NO |
dc.source.volume | 9 | nb_NO |
dc.source.journal | Dementia and geriatric cognitive disorders extra | nb_NO |
dc.source.issue | 1 | nb_NO |
dc.identifier.doi | 10.1159/000496537 | |
dc.identifier.cristin | 1746384 | |
cristin.unitcode | 217,13,0,0 | |
cristin.unitname | Det helsevitenskapelige fakultet | |
cristin.ispublished | true | |
cristin.qualitycode | 1 | |