dc.contributor.author | Haarr, Marianne Bore | |
dc.contributor.author | Lindback, Emil | |
dc.contributor.author | Håland, Torfinn | |
dc.contributor.author | Sydnes, Magne Olav | |
dc.date.accessioned | 2023-07-18T08:44:41Z | |
dc.date.available | 2023-07-18T08:44:41Z | |
dc.date.created | 2018-07-06T00:57:48Z | |
dc.date.issued | 2018-07 | |
dc.identifier.citation | Haarr, M.B., Lindbäck, E., Håland, T., & Sydnes, M.O. (2018) Synthesis of an Alleged Byproduct Precursor in Iodixanol Preparation. ACS Omega, 3 (7), 7344-7349. | en_US |
dc.identifier.issn | 2470-1343 | |
dc.identifier.uri | https://hdl.handle.net/11250/3079680 | |
dc.description.abstract | N1,N3-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(N-(oxiran-2-ylmethyl)acetamido)isophthalamide (1), the alleged precursor of several minor byproducts formed when the X-ray contrast agent iodixanol is synthesized from 5-acetamido-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide (2), has been successfully prepared with an overall yield of 25%. Epoxide 1 enabled the confirmation of its presence in the reaction mixture during the preparation of iodixanol when amide 2 was used as the starting material. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | American Chemical Society | en_US |
dc.rights | Navngivelse-Ikkekommersiell 4.0 Internasjonal | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/4.0/deed.no | * |
dc.subject | kjemi | en_US |
dc.title | Synthesis of an Alleged Byproduct Precursor in Iodixanol Preparation | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | © 2018 American Chemical Society | en_US |
dc.subject.nsi | VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440 | en_US |
dc.source.pagenumber | 7344-7349 | en_US |
dc.source.volume | 3 | en_US |
dc.source.journal | ACS Omega | en_US |
dc.source.issue | 7 | en_US |
dc.identifier.doi | 10.1021/acsomega.8b00411 | |
dc.identifier.cristin | 1596039 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |