Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Issue Date
Now showing items 101-120 of 498
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Kinase chemodiversity from the Arctic: the breitfussins
(Journal article; Peer reviewed, 2019-10)In this work, we demonstrate that the indole-oxazole-pyrrole framework of the breitfussin family of natural products is a promising scaffold for kinase inhibition. Six new halogenated natural products, breitfussin C–H (3 ... -
Effects of rockfill dams and rock dumps on downstream water chemistry
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-10-28)A number of potential negative effects on aquatic environments are associated with rockfills. However, in southwestern Norway, lakes and rivers downstream from large rockfills were among the very few sites where trout ... -
Regioselective Syntheses and Functionalizations of Polycyclic Aromatic Hydrocarbons: Directed Metalation and C─H Activation
(PhD thesis UiS;484, Doctoral thesis, 2019-12)Polycyclic aromatic hydrocarbons (PAHs) are well-known as pollutants and carcinogenic compounds. Lately, considering their opto-electronic and photophysical properties, PAHs are being developed as materials to be used in ... -
Evaluation of microalgae nutrient removal efficiency from wastewater cultivated in a photobioreactor under non-ideal conditions.
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-12-14)The scope of this project is to Study the long-term performance and wastewater nutrients removal efficiency by microalgae in a PBR under no favourable conditions. COD, TN, TP, NH4+-N, NO3--N, PO43--P, TSS and pH values ... -
Aquatic ecotoxicological assessment of sediments collected in Bergen using in vitro bioassays based on fish cell lines
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-12-15)Bergen is located along the coast in western Norway and is the second biggest city in the country, acting as a gateway to oceans and fjords in the region featuring extensive fish populations. As such, environmental evaluation ... -
Exploring Analytical Methods for Quality Control and Accurate Quantification of Major Biologically Active Components in Astragalus Radix
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)Abstract Introduction Over the past decade, the worldwide consumption and sales of Traditional Chinese Medicine (TCM) herbs have grown enormously. Astragalus Radix (Chinese: Huang qi) (AR), the dried root of Astragalus ... -
Optimization of the Inoculum-to-Substrate Ratio in Solid-State Spent Coffee Grounds Anaerobic Digestion Biorefineries Using Anaerobic Sludge for Maximal Bio-CH4 Production.
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)The optimization of bio-CH4 production from spent coffee grounds (SCGs) using anaerobic sludge (AS) under different inoculum-to-substrate ratios (ISRs) using solid-state batch-fed anaerobic digestion (AD) reactors was ... -
The influence of terrain on the mean wind flow characteristics in a fjord
(Peer reviewed; Journal article, 2020)Flow conditions in complex terrains such as fjords are highly three-dimensional and thus not properly captured by the wind flow models developed for homogenous terrains. In the present study, we explore the potential of ... -
Homeostasis by depression kinetics with multisite inhibition and positive feedback
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)In order to survive all living organisms must, to some extent, be able to adapt to the changes in environment.In recent years there have been proposed different controller motifs that are used to explain how does the ... -
Finite-temperature single molecule vibrational dynamics from combined density functional tight binding extended lagrangian dynamics simulations and time series analysis
(Peer reviewed; Journal article, 2020)Combining a computationally efficient and affordable molecular dynamics approach, based on atom-centered density matrix propagation scheme, with the density functional tight binding semiempirical quantum ... -
The escherichia coli alkA gene is activated to alleviate mutagenesis by an oxidized deoxynucleoside
(Peer reviewed; Journal article, 2020)The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine ... -
DNA damage and health effects in juvenile haddock (Melanogrammus aeglefinus) exposed to PAHs associated with oil-polluted sediment or produced water
(Peer reviewed; Journal article, 2020)The research objective was to study the presence of DNA damages in haddock exposed to petrogenic or pyrogenic polyaromatic hydrocarbons (PAHs) from different sources: 1) extracts of oil produced water (PW), dominated by ... -
Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua)
(Peer reviewed; Journal article, 2020)The aim of the present study was to investigate effects of defined mixtures of polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs), at low, environmentally relevant (1× = L), or high (20× = H) ... -
Statistical Approaches for Dissolution Profile Comparisons of Metformin Film-Coated Tablets
(Peer reviewed; Journal article, 2020)The objective of this work was to apply several statistical approaches to profile comparison on dissolution data of Metformin immediate release film-coated tablets to assure that the developed formulation of the test product ... -
Solvent Synergists for Improved Kinetic Hydrate Inhibitor Performance of Poly(N-vinylcaprolactam)
(Peer reviewed; Journal article, 2020)The synergetic effect of a range of different solvents on the kinetic hydrate inhibitor (KHI) performance of poly(N-vinylcaprolactam) (PVCap) has been investigated. The equipment used was a high-pressure (76 bar) rocking ... -
Plasma Activated Water: The Next Generation Technology for Food and Agricultural Applications
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)Plasma activated water (PAW) has recently gained increased attention as a next generation non-thermal food processing technology. It has promising potential as a eco-friendly alternative to traditional decontamination ... -
Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden
(Peer reviewed; Journal article, 2020)To disentangle the association between impulsive and compulsive behaviors (ICBs), health-related quality of life (HRQOL), satisfaction with life (SwL), and caregiver distress in dyads of people with Parkinson's disease ... -
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers
(Peer reviewed; Journal article, 2020)Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in ... -
Evolutionary Maintenance of the PTS2 Protein Import Pathway in the Stramenopile Alga Nannochloropsis
(Peer reviewed; Journal article, 2020)The stramenopile alga Nannochloropsis evolved by secondary endosymbiosis of a red alga by a heterotrophic host cell and emerged as a promising organism for biotechnological applications, such as the production of polyunsaturated ... -
Differential transcript usage in the Parkinson’s disease brain
(Peer reviewed; Journal article, 2020)Studies of differential gene expression have identified several molecular signatures and pathways associated with Parkinson’s disease (PD). The role of isoform switches and differential transcript usage (DTU) remains, ...