• A systematic review of associations between common SNCA variants and clinical heterogeneity in Parkinson's disease 

  Pedersen, Camilla C; Lange, Johannes; Førland, Marthe Gurine; Macleod, Angus D.; Alves, Guido Werner; Maple-Grødem, Jodi (Peer reviewed; Journal article, 2021-07)

  There is great heterogeneity in both the clinical presentation and rate of disease progression among patients with Parkinson’s disease (PD). This can pose prognostic difficulties in a clinical setting, and a greater ...

• Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients 

  Szwedo, Aleksandra A; Pedersen, Camilla C; Ushakova, Anastasia; Forsgren, Lars; Tysnes, Ole-Bjørn; Counsell, Carl E.; Alves, Guido Werner; Lange, Johannes; Macleod, Angus D.; Maple-Grødem, Jodi (Peer reviewed; Journal article, 2021-02)

  Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based ...

• Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein 

  Tesfahun, Almaz Nigatu; Alexeeva, Marina; Tomkuvienė, Miglė; Arshad, Aysha; Guragain, Prashanna; Klungland, Arne; Klimašauskas, Saulius; Ruoff, Peter; Bjelland, Svein (Peer reviewed; Journal article, 2021-06)

  DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ...

• Plasma-derived exosome-like vesicles are enriched in lyso-phospholipids and pass the blood-brain barrier 

  Jakubec, Martin; Maple-Grødem, Jodi; Akbari, Saleha; Nesse, Susanne; Halskau, Øyvind; Mork-Jansson, Astrid Elisabeth (Peer reviewed; Journal article, 2020-09)

  Exosomes are vesicles involved in intercellular communication. Their membrane structure and core content is largely dependent on the cell of origin. Exosomes have been investigated both for their biological roles and their ...

• Engineered methanotrophic syntrophy in photogranule communities removes dissolved methane 

  Safitri, Anissa Sukma; Hamelin, Jerome; Kommedal, Roald; Milferstedt, Kim (Peer reviewed; Journal article, 2021-06)

  The anaerobic treatment of wastewater leads to the loss of dissolved methane in the effluent of the treatment plant, especially when operated at low temperatures. The emission of this greenhouse gas may reduce or even ...

• Thermochemical splitting of CO2 using solution combustion synthesized lanthanum–strontium–manganese perovskites 

  Takalkar, Gorakshnath; Bhosale, Rahul R.; AlMomani, Fares; Rashid, Suliman; Qiblawey, Hazim; Saleh Saad, Mohammed Ali; Khraisheh, Majeda; Kumar, Gopalakrishnan; Gupta, Ram B.; Shende, Rajesh V. (Peer reviewed; Journal article, 2021-09)

  Redox reactivity of La(1-x)SrxMnO3 (LSM) perovskites towards a solar thermochemical CO2 splitting (CS) cycle is investigated. The LSM perovskites are synthesized via a solution combustion synthesis (SCS) method using glycine ...

• Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein 

  Kvivik, Ingeborg; Jonsson, Grete; Omdal, Roald; Brede, Cato (Peer reviewed; Journal article, 2021-06)

  Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...

• Entamoeba invadens; a study about the role of PLD1 and PLD2 in encystation 

  Kaneez, Fatima (Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-12)

  One of the most common problem in the developing world is infectious diseases caused by poor living conditions and one such condition is called amoebiasis. The causative agent of which is Entamoeba histolytica; a ...

• Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities 

  Håheim, Katja Stangeland; Lindback, Emil; Tan, Kah Ni; Albrigtsen, Marte; Helgeland, Ida Therese Urdal; Clemence, Lauga; Matringe, Theodora; Kennedy, Emily K.; Andersen, Jeanette Hammer; Avery, Vicky M.; Sydnes, Magne Olav (Peer reviewed; Journal article, 2021-05)

  A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the ...

• Synthesis of Phenacene−Helicene Hybrids by Directed Remote Metalation 

  Kancherla, Sindhu; Jørgensen, Kåre Bredeli (Peer reviewed; Journal article, 2020-08)

  Polycyclic aromatic hydrocarbons (PAHs) with six and seven rings were synthesized via directed metalation and cross-coupling of chrysenyl N,N-diethyl carboxamides with o-tolyl and methylnaphthalenyl derivatives. In the ...

• Directed ortho-Metalation and Anionic ortho-Fries Rearrangement of Polycyclic Aromatic O-Carbamates: Regioselective Synthesis of Substituted Chrysenes 

  Kancherla, Sindhu; Lorentzen, Marianne; Snieckus, Victor; Jørgensen, Kåre Bredeli (Peer reviewed; Journal article, 2018-03)

  A general method for the regioselective synthesis of a series of ortho-substituted chrysenyl N,N-diethyl-O-carbamates by the directed ortho-metalation (DoM) strategy is reported. The starting O-carbamates were prepared ...

• Multi-targeted trehalose-6-phosphate phosphatase I harbors a novel peroxisomal targeting signal 1 and is essential for flowering and development 

  Kataya, Amr Ramzy Abass; ElShobaky, Ahmed; Heidariahootapeh, Behzad; Nemie-Feyissa, Dugassa; Thelen, Jay J.; Lillo, Cathrine (Peer reviewed; Journal article, 2020-04)

  A putative, non-canonical peroxisomal targeting signal type 1 (PTS1) Pro-Arg-Met > was identified in the extreme C-terminus of trehalose-6-phosphate phosphatase (TPP)I. TPP catalyzes the final step of trehalose synthesis, ...

• The world Polleniidae (Diptera, Oestroidea): key to genera and checklist of species 

  Gisondi, Silva; Rognes, Knut; Badano, Davide; Pape, Thomas; Cerretti, Pierfilippo (Peer reviewed; Journal article, 2020-09)

  A key to the world genera and a checklist of the world species for the family Polleniidae, including distributions, are provided. The following taxonomic and nomenclatural changes are proposed: Nitellia hermoniella Lehrer, ...

• Permeability evolution of shear failing chalk cores under thermochemical influence 

  Kallesten, Emanuela Iedidia; Andersen, Pål Østebø; Madland, Merete Vadla; Korsnes, Reidar Inge; Omdal, Edvard; Zimmermann, Udo (Peer reviewed; Journal article, 2020-04)

  Development of petroleum reservoirs, including primary depletion of the pore pressure and repressurization during water injection naturally, leads to changes in effective stresses of the formations. These changes impose ...

• An amplified derepression controller with multisite inhibition and positive feedback 

  Drobac, Gorana; Waheed, Qaiser; Heidari, Behzad; Ruoff, Peter (Peer reviewed; Journal article, 2021-03)

  How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. ...

• Performance of Waterborne Polyurethanes in Inhibition of Gas Hydrate Formation and Corrosion: Influence of Hydrophobic Fragments 

  Pavelyev, Roman S.; Zaripova, Yulia F.; Yarkovoi, Vladimir V.; Vinogradova, Svetlana S.; Razhabov, Sherzod; Khayarov, Khasan R.; Nazarychev, Sergei A.; Stoporev, Andrey S.; Mendgaziev, Rais I.; Semenov, Anton P.; Valiullin, Lenar R.; Varfolomeev, Mikhail A.; Kelland, Malcolm Andrew (Peer reviewed; Journal article, 2020-12)

  The design of new dual-function inhibitors simultaneously preventing hydrate formation and corrosion is a relevant issue for the oil and gas industry. The structure-property relationship for a promising class of hybrid ...

• Biological effects of pharmaceuticals around a marine wastewater outfall – a case study in Rogaland, Norway 

  Vastveit, Julie (Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-01)

  In this thesis, farmed Mytilus edulis were caged and deployed at three locations at the coastline of the North Sea to monitor the potential biological effect related to the presence of pharmaceuticals in the marine ...

• Anaerobic Fungi: Past, Present, and Future 

  Hess, Matthias; Paul, Shyam S.; Puniya, Anil K.; van der Giezen, Mark; Shaw, Claire; Edwards, Joan E.; Fliegerova, Katerina (Peer reviewed; Journal article, 2020-10)

  Anaerobic fungi (AF) play an essential role in feed conversion due to their potent fiber degrading enzymes and invasive growth. Much has been learned about this unusual fungal phylum since the paradigm shifting work of ...

• Biohydrogen production from industrial wastewater: An overview 

  Preethi, *; Usman, T.M. Mohamed; Banu, Jeyakumar Rajesh; Gunasekaran, Muniappan; Kumar, Gopalakrishnan (Peer reviewed; Journal article, 2019-09)

  Biohydrogen production from industrial wastewater has been a focus of interest in recent years. The in depth knowledge in lab scale parameters and emerging strategies are needed to be investigated in order to implement the ...

• A modelling study of environmental fate and effects of oil leakage from abandoned wells 

  Pham, Hanh Thi Hong (Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-15)

  Potential environmental consequences of oil leakages are taken into consideration in the ongoing development of plug and abandonment (P&A) activities on the Norwegian Continental Shelf (NCS). The P&A on the NCS has been ...

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