Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Title
Now showing items 1-20 of 539
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1,4-Dideoxy-1,4-imino‑D‑arabinitol (DAB) Analogues Possessing a Hydrazide Imide Moiety as Potent and Selective α‑Mannosidase Inhibitors
(Peer reviewed; Journal article, 2020-07)The synthesis of two polyhydroxylated pyrrolidines as 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) analogues bearing a hydrazide moiety is described. The DAB analogues act as selective and potent inhibitors of α-mannosidase ... -
3D in vitro cancer models for drug screening: A study of glucose metabolism and drug response in 2D and 3D culture models
(PhD thesis UiS;, Doctoral thesis, 2022-03)Current drug screening protocols use in vitro cancer cell panels grown in 2D to evaluate drug response and select the most promising candidates for further in vivo testing. Most drug candidates fail at this stage, not ... -
5-Methyl-3-vinyl-2-oxazolidinone-Investigations of a New Monomer for Kinetic Hydrate Inhibitor Polymers
(Peer reviewed; Journal article, 2022)Kinetic hydrate inhibitors (KHIs) are polymers used in a chemical method to prevent gas hydrate plugging of oil and gas production flow lines. The main ingredient in a KHI formulation is one or more water-soluble amphiphilic ... -
A Bioprinting Workflow for Live Cell Imaging and Mechanical Testing
(Master thesis, 2023)Bioprinting, an emergent field bridging biology, chemistry and 3D printing technology offers to researchers innovative solutions to progress the study of tissue engineering, drug testing and cellular studies. This thesis ... -
A complete synthesis of an N-spirofused iminosugar from L-xylose; a potential cholinesterase inhibitor for treatment of Alzheimer’s disease
(Bachelor thesis, 2022)In this bachelor’s project we present a complete synthesis of an N-spirofused iminosugar II with a stable positive charge on the spirocyclic nitrogen atom that together with the hydroxyl groups are expected to establish ... -
A complete synthesis of an N-spirofused iminosugar from L-xylose; a potential cholinesterase inhibitor for treatment of Alzheimer’s disease
(Bachelor thesis, 2022)In this bachelor’s project we present a complete synthesis of an N-spirofused iminosugar II with a stable positive charge on the spirocyclic nitrogen atom that together with the hydroxyl groups are expected to establish ... -
A computational model of DOPA regulation, dopamine synthesis in the presynaptic neuron, and release into the synaptic cleft
(Master thesis, 2022)Background: Neurotransmitters and the way neurons communicate with each other have received a lot of attention in recent decades. Dopamine is one of the most important neurotransmitters. Unbalanced levels of dopamine can ... -
A feasibility study of piggery wastewater as a cost-effective media using sodium alginate immobilized microalgae
(Master thesis, 2023)In recent years, microalgal biotechnology has experienced significant growth across multiple industry sectors due to the versatility of various microalgae species. Manny applications for both microalgae themselves and ... -
A review of metal recovery from E-waste using current microbial technologies
(Master thesis, 2023)With the increasing demand for metals in many industries, there is a growing need for improved methods of metal recovery. For the management of electronic waste (E-waste), numerous studies have been conducted on extracting ... -
A Study on Multi-Functional Oilfield Production Chemicals for Scale, Corrosion and Gas Hydrates
(Master thesis, 2022)Oilfield production chemistry is a wide field which includes many different areas and related difficulties. In this work, focus is on mitigating scale, corrosion, and gas hydrates using chemical inhibitors. Production lines ... -
A Top-Down Approach to Simplifying Carbon Emission Forecasting for Improved Project Development and Environmental Accounting in Offshore Oil and Gas Production
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-30)A combination of factors including environmental, resource availability, investor weariness and public perception of the oil and gas industry challenge the competitiveness of the sector in Norway and around the world. One ... -
Adsorpsjon av per- og polyfluoroalkyler (PFAS) fra vann.
(Bachelor thesis, 2023)PFAS-forbindelser er mye brukt i brannslokkingsskum, non-stick panner, vanntette klær, og mange andre ting som brukes i det vanlige livet. PFAS er karbonkjeder minst én eller alle hydrogener er substituert med et fluoridatom. ... -
Advances in the Study of Gas Hydrates by Dielectric Spectroscopy
(Peer reviewed; Journal article, 2021)The influence of kinetic hydrate inhibitors on the process of natural gas hydrate nucleation was studied using the method of dielectric spectroscopy. The processes of gas hydrate formation and decomposition were monitored ... -
Alexeeva, M., Moen, M.N., Grøsvik, K. et al (2018) Excision of uracil from DNA by hSMUG1 includes strand incision and processing.
(Journal article; Peer reviewed, 2018-11)Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. ... -
Alkyl-phenanthrenes in early life stage fish: differential toxicity in Atlantic haddock (Melanogrammus aeglefinus) embryos
(Peer reviewed; Journal article, 2023)Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene are known to have direct effects on cardiac tissue, which lead to ... -
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
(Peer reviewed; Journal article, 2021-06)DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ... -
Alpha-synuclein biomarkers of Parkinson's disease risk and heterogeneity
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020-06)Parkinson’s disease (PD) is the second most common neurodegenerative disease and is the world’s fastest growing neurological disorder. PD is a motor disease, but many patients experience a range of non-motor features, ... -
Altered transcriptome-proteome coupling indicates aberrant proteostasis in Parkinson's disease
(Peer reviewed; Journal article, 2023)Aberrant proteostasis is thought to be implicated in Parkinson’s disease (PD), but patient-derived evidence is scant. We hypothesized that impaired proteostasis is reflected as altered transcriptome-proteome correlation ... -
Alternative Lactam-Based Kinetic Hydrate Inhibitors - Investigation of Polymers of 2‑Methacrylamido-caprolactam
(Peer reviewed; Journal article, 2022)Kinetic hydrate inhibitors (KHIs), such as poly(N-vinylcaprolactam) (PVCap) and related copolymers, are a well-known method to help combat gas hydrate formation in oil and gas field production flow lines. The caprolactam ... -
Amine functionalized metal-organic framework for carbon capture
(Bachelor thesis, 2022)This thesis was all about synthesizing metal-organic frameworks, MOFs, with different compositions, and further on characterize and analyze the products using different measurements. The idea was to find out how we could ...