Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Issue Date
Now showing items 241-260 of 507
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Synthesis and Study of Modified Polyaspartic Acid Coupled Phosphonate and Sulfonate Moieties As Green Oilfield Scale Inhibitors
(Peer reviewed; Journal article, 2021)The petroleum industry has strived for several years to explore environmentally friendly scale inhibitors with no acute environmental impact. Well-known industrial biodegradable polyaspartic acid is widely used as a potent ... -
Lack of Association Between GBA Mutations and Motor Complications in European and American Parkinson's Disease Cohorts
(Peer reviewed; Journal article, 2021)Background: Motor complications are a consequence of the chronic dopaminergic treatment of Parkinson’s disease (PD) and include levodopa-induced dyskinesia (LIDs) and motor fluctuations (MF). Currently, evidence is on ... -
Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a
(Peer reviewed; Journal article, 2021)Polycyclic aromatic hydrocarbons (PAHs) are among the most toxic and bioavailable components found in petroleum and represent a high risk to aquatic organisms. The aryl hydrocarbon receptor (Ahr) is a ligand-activated ... -
Modeling of Environmental Fate and Effects of Oil Leakages from Abandoned Subsea Wells Using an Environmental Impact Factor Tool
(Peer reviewed; Journal article, 2021)Potential environmental consequences of oil leakages (i.e., continuous uncontrolled releases at low flow rate over a long period of time) need to be taken into consideration in the ongoing development of plug and abandonment ... -
Antiscaling Evaluation of Novel Non-Polymeric Phosphonates for Oilfield Applications
(Master thesis, 2021)Scale formation consists of an accumulation of mineral deposits, affecting fluids flow. It is a major flow assurance problem in the oilfield industry and can occur anywhere along water paths, from injectors through the ... -
Synthesis of the Hexahydropyrrolo‐[3,2‐c]‐quinoline Core Structure and Strategies for Further Elaboration to Martinelline, Martinellic Acid, Incargranine B, and Seneciobipyrrolidine
(Peer reviewed; Journal article, 2021-01)Natural products are rich sources of interesting scaffolds possessing a plethora of biological activity. With the isolation of the martinella alkaloids in 1995, namely martinelline and martinellic acid, the pyrrolo[3,2‐c]quinoline ... -
Association of SNCA Parkinson's Disease Risk Polymorphisms With Disease Progression in Newly Diagnosed Patients
(Peer reviewed; Journal article, 2021-02)Objectives: To evaluate the impact of SNCA polymorphisms originally identified as risk factors for Parkinson's disease (PD) on the clinical presentation and progression of the disease in a large cohort of population-based ... -
Diastereoselectivity in Anomeric O-alkylation Glycosylation
(PhD thesis UiS;, Doctoral thesis, 2021-02)Biosynth AS used anomeric O-alkylation of α-haloacetophenones in their patented total synthesis of anthocyanins from 2006. There were, however, several challenges with stereoselectivity and yields when performing this ... -
An amplified derepression controller with multisite inhibition and positive feedback
(Peer reviewed; Journal article, 2021-03)How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. ... -
Nutraceutical productions from microalgal derived compounds via circular bioeconomy perspective
(Peer reviewed; Journal article, 2021-03)Circular bioeconomy has become a sustainable business model for commercial production that promises to reuse, recycle & recover while considering less environmental footprints in nutraceutical industries. Microalgae ... -
Protein phosphatase 2A as a regulator and mediator of beneficial plant-microbe interactions
(PhD thesis UiS;, Doctoral thesis, 2021-03)Protein phosphatase 2A (PP2A) is involved in the regulation of stress response, growth and hormone signalling during the plant life cycle. A variety of plant growth-promoting rhizobacteria (PGPR) and arbuscular mycorrhiza ... -
Pinpointing regulatory protein phosphatase 2A subunits involved in beneficial symbiosis between plants and microbes
(Peer reviewed; Journal article, 2021-04)Background PROTEIN PHOSPHATASE 2A (PP2A) expression is crucial for the symbiotic association between plants and various microbes, and knowledge on these symbiotic processes is important for sustainable agriculture. Here ... -
Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids
(Peer reviewed; Journal article, 2021-04)The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ... -
The Asgard Archaeal-Unique Contribution to Protein Families of the Eukaryotic Common Ancestor Was 0.3%
(Peer reviewed; Journal article, 2021-04)The identification of the asgard archaea has fueled speculations regarding the nature of the archaeal host in eukaryogenesis and its level of complexity prior to endosymbiosis. Here, we analyzed the coding capacity of 150 ... -
Early constipation predicts faster dementia onset in Parkinson's disease
(Peer reviewed; Journal article, 2021-05)Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ... -
Synthesis and Evaluation of the Tetracyclic Ring-System of Isocryptolepine and Regioiso-Mers for Antimalarial, Antiproliferative and Antimicrobial Activities
(Peer reviewed; Journal article, 2021-05)A series of novel quinoline-based tetracyclic ring-systems were synthesized and evaluated in vitro for their antiplasmodial, antiproliferative and antimicrobial activities. The novel hydroiodide salts 10 and 21 showed the ... -
Tropical fruit waste-derived mesoporous rock-like Fe2O3/Ccomposite fabricated with amphiphilic surfactant-templating approach showing massive potential for high-tech applications
(Peer reviewed; Journal article, 2021-05)Recently, the glycolipids biosurfactant materials have widely been utilized for many industrial applications due to their feasible surface activity, biodegradable as well as eco-friendly nature. Even though many of the ... -
Alleviation of C⋅C Mismatches in DNA by the Escherichia coli Fpg Protein
(Peer reviewed; Journal article, 2021-06)DNA polymerase III mis-insertion may, where not corrected by its 3′→ 5′ exonuclease or the mismatch repair (MMR) function, result in all possible non-cognate base pairs in DNA generating base substitutions. The most ... -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
(Peer reviewed; Journal article, 2021-06)Recent preclinical studies have shown that interstitial fluid pressure (IFP) within tumors can be heterogeneous Andersen et al. (2019). In that study tumors of two xenograft models, respectively, HL-16 cervical carcinoma ... -
Sample Preparation Strategies for Antibody-Free Quantitative Analysis of High Mobility Group Box 1 Protein
(Peer reviewed; Journal article, 2021-06)Sickness behavior and fatigue are induced by cerebral mechanisms involving inflammatory cytokines. High mobility group box 1 (HMGB1) is an alarmin, and a potential key player in this process. Reliable quantification methods ...