Blar i Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) på tittel
Viser treff 205-224 av 498
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Homeostasis by depression kinetics with multisite inhibition and positive feedback
(Masteroppgave/UIS-TN-IKBM/2020;, Master thesis, 2020)In order to survive all living organisms must, to some extent, be able to adapt to the changes in environment.In recent years there have been proposed different controller motifs that are used to explain how does the ... -
Homeostatic controllers compensating for growth and perturbations
(Journal article; Peer reviewed, 2019-08)Cells and organisms have developed homeostatic mechanisms which protect them against a changing environment. How growth and homeostasis interact is still not well understood, but of increasing interest to the molecular and ... -
Homologous Recombination Deficiency Across Subtypes of Primary Breast Cancer
(Peer reviewed; Journal article, 2023)Purpose Homologous recombination deficiency (HRD) is highly prevalent in triple-negative breast cancer (TNBC) and associated with response to PARP inhibition (PARPi). Here, we studied the prevalence of HRD in non-TNBC to ... -
hUNG activity for uracil in bubble and R-loop DNA
(Master thesis, 2021)Uracil, a common base in RNA, may arise in cellular DNA by cytosine deamination or during replication through the misincorporation of deoxyuridine monophosphate instead of thymidine monophosphate. Repair of uracil is ... -
A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)
(Peer reviewed; Journal article, 2022)The synthesis of four heterodimers in which the copper(I)-catalysed azide-alkyne cycloaddition was employed to connect a 1-deoxynojirimycin moiety with a benzotriazole scaffold is reported. The heterodimers were investigated ... -
Hydraulic Behaviour: A Tracer Study of a Stormwater Detention and Sedimentation System
(Master thesis, 2023)Stormwater is of growing concern with increased heavy rainfall and runoff surfaces from urbanisation. The challenges of stormwater has two aspects; risk of flooding and risk of pollution. Road runoff in particular, can at ... -
Identification of Arabidopsis Protein Kinases That Harbor Functional Type 1 Peroxisomal Targeting Signals
(Peer reviewed; Journal article, 2022)Peroxisomes are eukaryotic specific organelles that perform diverse metabolic functions including fatty acid β-oxidation, reactive species metabolism, photorespiration, and responses to stress. However, the potential ... -
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach
(Peer reviewed; Journal article, 2023-10)Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of ... -
Identification of diagnostic and prognostic biomarkers of PD using a multiplex proteomics approach
(Peer reviewed; Journal article, 2023-09)Given the complexity of Parkinson's disease (PD), achieving acceptable diagnostic and prognostic accuracy will require the support of a panel of diverse biomarkers. We used Proximity extension assays to measure a panel of ... -
Impact of KRAS and BRAF mutations on treatment efficacy and survival in high-grade gastroenteropancreatic neuroendocrine neoplasms
(Peer reviewed; Journal article, 2023)High-grade gastroenteropancreatic neuroendocrine neoplasms (HG GEP-NEN) typically disseminate early. Treatment of metastatic disease has limited benefit and prognosis is generally discouraging. Data on the clinical impact ... -
Implementing fish cell line assays to study functional feed ingredients.
(Master thesis, 2023)There is an increase in demand for fish and aquaculture around the world. When the demand increase challenges arise such as sustainability, welfare and cost. There have been raised concerns due to the feed the farmed ... -
Implication of forms and distribution of phosphorous in sediments of three Stavanger lakes and ponds of constructed wetland on the potential for sedimentary phosphorous release and future eutrophication.
(Masteroppgave/UIS-TN-IKBM/2018;, Master thesis, 2018-07-27)Excess of bioavailable phosphorus in fresh-water systems results in algal blooms and subsequent biogeochemical activities which in turn as positive feedback can escalate eutrophication and significantly reduce water quality. ... -
Improved pH-Responsive Release of Phenformin from Low-Defect Graphene Compared to Graphene Oxide
(Peer reviewed; Journal article, 2021-09)Graphene-based drug carriers provide a promising addition to current cancer drug delivery options. Increased accessibility of high-quality graphene made by plasma-enhanced chemical vapor deposition (PE-CVD) makes it an ... -
Improving and evaluating methods of the analysis of microplastics from environmental samples
(Masteroppgave/UIS-TN-IKBM/2019;, Master thesis, 2019-06-15)The objective of this thesis was to improve the methodology in the studies of the microplastics (MPs) in the laboratory and from environmental samples. The main application for this purpose was by the use of a quality ... -
Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
(Peer reviewed; Journal article, 2022)Background Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed ... -
Impulsive and compulsive behaviors in Parkinson's disease: Impact on quality of and satisfaction with life, and caregiver burden
(Peer reviewed; Journal article, 2020)To disentangle the association between impulsive and compulsive behaviors (ICBs), health-related quality of life (HRQOL), satisfaction with life (SwL), and caregiver distress in dyads of people with Parkinson's disease ... -
In silico investigations of intratumoral heterogeneous interstitial fluid pressure
(Peer reviewed; Journal article, 2021-06)Recent preclinical studies have shown that interstitial fluid pressure (IFP) within tumors can be heterogeneous Andersen et al. (2019). In that study tumors of two xenograft models, respectively, HL-16 cervical carcinoma ... -
In vitro cytotoxicity testing to evaluate inlet and outlet water samples from a wastewater treatment plant.
(Bachelor thesis, 2021)The obtained results showed an adverse outcome using both the cell lines, in the two types of samples, inlet and outlet. -
In vivo biodistribution of lipid nanoparticles in zebrafish embryo
(Bachelor thesis, 2023)Nanoparticles (NPs) are particles within the size range of 1-100 nm with distinctive surface structures that can act as transport particles of numerous substances. These properties allow for applications in a variety of ...