• An amplified derepression controller with multisite inhibition and positive feedback 

      Drobac, Gorana; Waheed, Qaiser; Heidari, Behzad; Ruoff, Peter (Peer reviewed; Journal article, 2021-03)
      How organisms are able to maintain robust homeostasis has in recent years received increased attention by the use of combined control engineering and kinetic concepts, which led to the discovery of robust controller motifs. ...
    • DOPA Homeostasis by Dopamine: A Control-Theoretic View 

      Kleppe, Rune; Waheed, Qaiser; Ruoff, Peter (Peer reviewed; Journal article, 2021-11)
      Dopamine (DA) is an important signal mediator in the brain as well as in the periphery. The term “dopamine homeostasis” occasionally found in the literature refers to the fact that abnormal DA levels can be associated with ...
    • Frequency switching between oscillatory homeostats and the regulation of p53 

      Ruoff, Peter; Nishiyama, Nobuaki (Peer reviewed; Journal article, 2020-05)
      Homeostasis is an essential concept to understand the stability of organisms and their adaptive behaviors when coping with external and internal assaults. Many hormones that take part in homeostatic control come in ...
    • Homeostatic controllers compensating for growth and perturbations 

      Ruoff, Peter; Agafonov, Oleg; Tveit, Daniel Myklatun; Thorsen, Kristian; Drengstig, Tormod (Journal article; Peer reviewed, 2019-08)
      Cells and organisms have developed homeostatic mechanisms which protect them against a changing environment. How growth and homeostasis interact is still not well understood, but of increasing interest to the molecular and ...
    • Model Development and Investigations on Ion Homeostasis 

      Selstø, Christina Helen (PhD thesis UiS;, Doctoral thesis, 2023-05)
      The environment surrounding an organism, a cell and an organelle is constantly changing. To keep organisms functioning there is an everlasting need to regulate and adapt in order to keep the internal environment relatively ...