Browsing Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) by Subject "nevrologi"
Now showing items 1-6 of 6
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Association of GBA Genotype With Motor and Functional Decline in Patients With Newly Diagnosed Parkinson Disease.
(Peer reviewed; Journal article, 2020-12)Objective To establish the significance of glucocerebrosidase gene (GBA) carrier status on motor impairment in a large cohort of patients with incident Parkinson disease (PD). Methods Three European population-based ... -
Combinatory microRNA serum signatures as classifiers of Parkinson's disease
(Journal article; Peer reviewed, 2019-04)As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ... -
Early constipation predicts faster dementia onset in Parkinson's disease
(Peer reviewed; Journal article, 2021-05)Constipation is a common but not a universal feature in early PD, suggesting that gut involvement is heterogeneous and may be part of a distinct PD subtype with prognostic implications. We analysed data from the Parkinson’s ... -
Excessive Daytime Sleepiness and REM Sleep Behavior Disorders in Parkinson's Disease: A Narrative Review on Early Intervention With Implications to Neuroprotection
(Journal article; Peer reviewed, 2018-11)Sleep contributes to the consolidation of our memory and facilitates learning. Short term sleep deprivation temporarily reduces mnestic capacity, whereas long lasting sleep deprivation is associated with structural changes ... -
First delirium episode in Parkinson’s disease and parkinsonism: incidence, predictors, and outcomes
(Peer reviewed; Journal article, 2021-10)To define the incidence, predictors and prognosis of the first hospital delirium episode in Parkinson’s disease (PD) and atypical parkinsonism (AP), we identified the first hospital episode of delirium after diagnosis in ... -
Meta-analysis of whole-exome sequencing data from two independent cohorts finds no evidence for rare variant enrichment in Parkinson disease associated loci
(Peer reviewed; Journal article, 2020-10)Parkinson disease (PD) is a complex neurodegenerative disorder influenced by both environmental and genetic factors. While genome wide association studies have identified several susceptibility loci, many causal variants ...