Blar i Department of Chemistry, Bioscience and Environmental Engineering (TN-IKBM) på emneord "peptider"

Viser treff 1-2 av 2

    • Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids 

      Hassan, Ashraf S.; Moustafa, Gaber O.; Awad, Hanem M.; Nossier, Eman S.; Mady, Mohamed Fawzy Hamed Attia (Peer reviewed; Journal article, 2021-04)
      The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ...

    • Kinase chemodiversity from the Arctic: the breitfussins 

      Østnes Hansen, Kine; Andersen, Jeanette hammer; Bayer, Annette; Pandey, Sunil Kumar; Lorentzen, Marianne; Jørgensen, Kåre Bredeli; Sydnes, Magne Olav; Guttormsen, Yngve; Baumann, Matthias; Koch, Uwe; Klebl, Bert; Eickhoff, Jan; Haug, Bengt Erik; Isaksson, Johan; Hansen, Espen (Journal article; Peer reviewed, 2019-10)
      In this work, we demonstrate that the indole-oxazole-pyrrole framework of the breitfussin family of natural products is a promising scaffold for kinase inhibition. Six new halogenated natural products, breitfussin C–H (3 ...