Blar i Vitenskapelige publikasjoner (TN-IKBM) på tittel
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Coherent feedback leads to robust background compensation in oscillatory and non-oscillatory homeostats
(Peer reviewed; Journal article, 2023-08)When in a reaction kinetic integral controller a step perturbation is applied besides a constant background, the concentration of a controlled variable (described as A) will generally respond with decreased response ... -
Combinatory microRNA serum signatures as classifiers of Parkinson's disease
(Journal article; Peer reviewed, 2019-04)As current clinical diagnostic protocols for Parkinson's disease (PD) may be prone to inaccuracies there is a need to identify and validate molecular biomarkers, such as circulating microRNAs, which will complement current ... -
Combined Effect of Citric Acid and Polyphenol-Rich Grape Seed Extract towards Bioactive Smart Food Packaging Systems
(Peer reviewed; Journal article, 2023-07)Alginate films (2% w·v−1) were prepared with varying concentrations (5–20% w/w) of citric acid and aqueous grape seed extract (GSE) filtrate (11.66 ± 1.32 g GAE/L) using the solvent-evaporation method. Crosslinking alginate ... -
Combined Effect of Citric Acid and Polyphenol-Rich Grape Seed Extract towards Bioactive Smart Food Packaging Systems
(Peer reviewed; Journal article, 2023-07)Alginate films (2% w·v−1) were prepared with varying concentrations (5–20% w/w) of citric acid and aqueous grape seed extract (GSE) filtrate (11.66 ± 1.32 g GAE/L) using the solvent-evaporation method. Crosslinking alginate ... -
Combined HER3-EGFR score in triple-negative breast cancer provides prognostic and predictive significance superior to individual biomarkers
(Peer reviewed; Journal article, 2020)Epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3) have been investigated as triple-negative breast cancer (TNBC) biomarkers. Reduced EGFR levels can be compensated by increases in ... -
Comparative study on two deployment methods for large subsea spools
(Peer reviewed; Journal article, 2021-08)The demand for subsea spool deployment is increasing with the expansion of offshore projects. For a project to install multiple spools, different deployment methods can be used. The choice of method may influence the safety ... -
Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer
(Peer reviewed; Journal article, 2023)Purpose: Circulating tumor DNA (ctDNA) has emerged as a promising tumor-specific biomarker in pancreatic cancer, but current evidence of the clinical potential of ctDNA is limited. In this study, we used comprehensive ... -
Connecting gut microbiome changes with fish health conditions in juvenile Atlantic cod (Gadus morhua) exposed to dispersed crude oil
(Peer reviewed; Journal article, 2023)Polycyclic aromatic hydrocarbons found in crude oil can impair fish health following sublethal exposure. However, the dysbiosis of microbial communities within the fish host and influence it has on the toxic response of ... -
Cyclic production of biocompatible few-layer graphene ink with in-line shear-mixing for inkjet-printed electrodes and Li-ion energy storage
(Peer reviewed; Journal article, 2022)The scalable production of two-dimensional (2D) materials is needed to accelerate their adoption to industry. In this work, we present a low-cost in-line and enclosed process of exfoliation based on high-shear mixing to ... -
Deconvolution approach for floating wind turbines
(Peer reviewed; Journal article, 2023-05)Green renewable energy is produced by floating offshore wind turbines (FOWT), a crucial component of the modern offshore wind energy industry. It is a safety concern to accurately evaluate excessive weights while the FOWT ... -
Design, synthesis and antitumor evaluation of novel pyrazolopyrimidines and pyrazoloquinazolines
(Journal article; Peer reviewed, 2018-05)A series of N-aryl-7-aryl-pyrazolo[1,5-a]pyrimidines 18a–u and N-aryl-pyrazolo[1,5-a] quinazolines 25a–c were designed and synthesized via the reaction of 5-aminopyrazoles 11a–c with enaminones 12a–g or 19, respectively. ... -
Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole−Indole Hybrids
(Peer reviewed; Journal article, 2021-04)The molecular hybridization concept has recently emerged as a powerful approach in drug discovery. A series of novel indole derivatives linked to the pyrazole moiety were designed and developed via a molecular hybridization ... -
Development of a constitutive and an auto-inducible high-yield expression system for recombinant protein production in the microalga Nannochloropsis oceanica
(Peer reviewed; Journal article, 2020-09)Photoautotrophic microalgae offer a great potential as novel hosts for efficient recombinant protein production. Nannochloropsis oceanica produces an extraordinarily high content of polyunsaturated fatty acids, and its ... -
Development of tacrine clusters as positively cooperative systems for the inhibition of acetylcholinesterase
(Peer reviewed; Journal article, 2021-07)The synthesis of four tetra-tacrine clusters where the tacrine binding units are attached to a central scaffold via linkers of variable lengths is described. The multivalent inhibition potencies for the tacrine clusters ... -
Differential transcript usage in the Parkinson’s disease brain
(Peer reviewed; Journal article, 2020)Studies of differential gene expression have identified several molecular signatures and pathways associated with Parkinson’s disease (PD). The role of isoform switches and differential transcript usage (DTU) remains, ... -
Directed ortho-Metalation and Anionic ortho-Fries Rearrangement of Polycyclic Aromatic O-Carbamates: Regioselective Synthesis of Substituted Chrysenes
(Peer reviewed; Journal article, 2018-03)A general method for the regioselective synthesis of a series of ortho-substituted chrysenyl N,N-diethyl-O-carbamates by the directed ortho-metalation (DoM) strategy is reported. The starting O-carbamates were prepared ... -
Distinct Clades of Protein Phosphatase 2A Regulatory B’/B56 Subunits Engage in Different Physiological Processes
(Peer reviewed; Journal article, 2023-07)Protein phosphatase 2A (PP2A) is a strongly conserved and major protein phosphatase in all eukaryotes. The canonical PP2A complex consists of a catalytic (C), scaffolding (A), and regulatory (B) subunit. Plants have three ... -
Distinct Gene Expression Profiles of Matched Primary and Metastatic Triple-Negative Breast Cancers
(Peer reviewed; Journal article, 2022)Background: Although triple-negative breast cancer (TNBC) is associated with an increased risk of recurrence and metastasis, the molecular mechanisms underlying metastasis in TNBC remain unknown. To identify transcriptional ... -
DNA damage and health effects in juvenile haddock (Melanogrammus aeglefinus) exposed to PAHs associated with oil-polluted sediment or produced water
(Peer reviewed; Journal article, 2020)The research objective was to study the presence of DNA damages in haddock exposed to petrogenic or pyrogenic polyaromatic hydrocarbons (PAHs) from different sources: 1) extracts of oil produced water (PW), dominated by ... -
DOPA Homeostasis by Dopamine: A Control-Theoretic View
(Peer reviewed; Journal article, 2021-11)Dopamine (DA) is an important signal mediator in the brain as well as in the periphery. The term “dopamine homeostasis” occasionally found in the literature refers to the fact that abnormal DA levels can be associated with ...