Browsing Vitenskapelige publikasjoner (TN-IKBM) by Author "Moen, Marivi Nabong"
Now showing items 1-2 of 2
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Alexeeva, M., Moen, M.N., Grøsvik, K. et al (2018) Excision of uracil from DNA by hSMUG1 includes strand incision and processing.
Moen, Marivi Nabong; Grøsvik, Kristin; Kirpekar, Finn; Tesfahun, Almaz Nigatu; Ruoff, Peter; Klungland, Arne; Bjelland, Svein (Journal article; Peer reviewed, 2018-11)Uracil arises in DNA by hydrolytic deamination of cytosine (C) and by erroneous incorporation of deoxyuridine monophosphate opposite adenine, where the former event is devastating by generation of C → thymine transitions. ... -
Intrinsic Strand-Incision Activity of Human UNG: Implications for Nick Generation in Immunoglobulin Gene Diversification
Alexeeva, Marina; Moen, Marivi Nabong; Xu, Xiang Ming; Rasmussen, Anette; Leiros, Ingar; Kirpekar, Finn; Klungland, Arne; Alsøe, Lene; Nilsen, Hilde; Bjelland, Svein (Peer reviewed; Journal article, 2021)Uracil arises in cellular DNA by cytosine (C) deamination and erroneous replicative incorporation of deoxyuridine monophosphate opposite adenine. The former generates C → thymine transition mutations if uracil is not removed ...